BrainMap

Alexandra Canciu

- UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU"

Researcher | PhD student

Expertise & keywords

Nanoplatforms for the rapid electrochemical detection of Staphylococcus aureus by specific markers Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente - TE-2021
PN-III-P1-1.1-TE-2021-0846 2023 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU"

Project partners: UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)

Affiliation:

Project website: https://sites.google.com/view/starsens/home

Abstract:

Staphylococcus aureus (S. aureus) is a dangerous pathogenic agent responsible of many diseases, from mild to life-threatening ones, frequently causing healthcare-associated infections. Knowing the high risks that pathogens pose and their resistance to antibiotics, it is crucial to develop new methods for their early real-time detection to be able to initiate therapy and prevent severe complications. Electrochemical sensors emerged as alternatives to conventional methods (microbiological culture, ELISA, PCR) due to their advantages: high sensitivity and selectivity simplicity, low cost, short analysis time, robustness, possibility for portability (suitable for point-of-use/care devices). The purpose of StarSens is represented by the development of new strategies for rapid diagnosis of S. aureus infection through the electrochemical detection of Staphyloferrin A and Protein A, as specific markers. The project has several goals: (1) Development of nanostructured surfaces for the direct electrochemical detection of Staphyloferrin A, siderophore of S. aureus; (2) Development of an aptasensor for Protein A; (3) Evaluation of the (apta)sensors in real samples (human serum, real samples from volunteers, and culture plates). The foreseen results will contribute to advancing the know-how in the biomedical and analytical chemistry fields offering new perspectives for the development of novel (bio)sensors and methods applicable for microbiology diagnosis and therapeutic monitoring.

Pathogen Contamination Emergency Response Technologies Call name: EC - H2020
H2020-229396-883484 2020 - 2023

Role in this project: Key expert

Coordinating institution: UNIVERSITY OF CYPRUS

Project partners: UNIVERSITY OF CYPRUS (CY); ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS (EL); WATER EUROPE (BE); COMMUNICATION AND INFORMATION SYSTEMS DIRECTORATE (BG); AQUA-Q AB (SE); KWR WATER B.V. (NL); ETAIRIA HYDREFSIS KAI APOCHETEFSIS THESSALONIKIS AE (EL); SUNDOSOFT LTD (KR); UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA (RO); MINISTRY OF INTERIOR (CY); Korea Institute of Science and Technology (KR); ELLINIKI OMADA DIASOSIS SOMATEIO (EL); NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA (EL); MicroLAN (NL); CETAQUA, CENTRO TECNOLOGICO DEL AGUA, FUNDACION PRIVADA (ES); AYUNTAMIENTO DE GRANADA (ES); FUNDACIO EURECAT (ES); SATWAYS - PROIONTA KAI YPIRESIES TILEMATIKIS DIKTYAKON KAI TILEPIKINONIAKON EFARMOGON ETAIRIA PERIORISMENIS EFTHINIS EPE (EL); COLLABORATING CENTRE ON SUSTAINABLE CONSUMPTION AND PRODUCTION GGMBH (DE); STICHTING WATERNET (NL); FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE); PHOEBE RESEARCH AND INNOVATION LTD (CY); ENGINEERING - INGEGNERIA INFORMATICA SPA (IT); FUNDACION CENTRO ANDALUZ DE INVESTIGACIONES DEL AGUA (ES); EMPRESA MUNICIPAL DE ABASTECIMIENTO Y SANEAMIENTO DE GRANADA SA (ES); UNIVERSITY OF STUTTGART (DE); LABAQUA SA (ES)

Affiliation: UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA (RO)

Project website:

Abstract:

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List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
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Peer-review activity for international programs/projects