BrainMap

Alexandra Ciorita

- INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Other affiliations

PhD Student - UNIVERSITATEA BABES BOLYAI (Romania)

Teaching staff | Other

Publons/ResearcherID: not public

Expertise & keywords

Partnership for the transfer of innovative technologies and advanced materials in the field of visual arts (production, preservation, restoration) Call name:
ID P_40_374 2016 - 2021

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (); CORAMI FUNZIONE SRL (); DUCT SRL (); CENTRUL IT PENTRU STIINTA SI TEHNOLOGIE S.R.L. (); CENTRUL DE COMPETENTA IN ELECTROSTATICA SI ELECTROTEHNOLOGII S.R.L. (); DANART IMPORT EXPORT SRL (); ZAREDARTE SRL (); ARS VITREARUM AMAGA S.R.L. ()

Affiliation: UNIVERSITATEA BABES BOLYAI ()

Project website: http://tematicart.granturi.ubbcluj.ro/

Abstract:

Characterization of the sub-cellular effects of functionalised magnetic nanoparticles in targeted anti-tumor therapy Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-0608 2015 - 2017

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO)

Affiliation: UNIVERSITATEA BABES BOLYAI (RO)

Project website: http://poravpaul.wix.com/cellspion

Abstract:

Having unique magnetic properties, super-paramagnetic nanoparticles (SPIONs) are an efficient vector for anti-tumor targeted therapy, non-viral gene therapy, magnetic resonance imaging contrast agent, and thus personalized medicine. SPIONs are cheap and easy to synthesize, have determined dimensions, can be functionalized and loaded with various substances, and they can transport a certain drug to a certain area of the body in a targeted way, being conducted by magnet. They can be, this way, monitored in real time and at the area of interest SPIONs combine the chemical effect of the drug with the physical effect of the magnetic fluids induced hyperthermia, which generates selectively local overheating through an external magnetic field. In spite of all this promising features, there is still a certain holdback for using SPIONs as a nanotherapy method. This happens mostly because of the fact that nanomedicine is a new domain and because of the lack of coherence in all studies involving NPs in medical applications. Through our project we intend to integrate all aspects regarding cell-NPs interactions and to eliminate all dissonances that shows when passing from a certain study system to another (in vitro-2D-3D-in vivo), finally leading us to obtain coherent data. This is why this study is needed, a complete, integrating and complex study, which starts from NPs synthesis, bioavailability, cytostatic loading, fluorescent loading, in vitro and then in vivo, up to clearance.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects