BrainMap

Alexandra Ciorita

PhD

- UNIVERSITATEA BABES BOLYAI

Other affiliations

Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (Romania)

Researcher | Teaching staff | Scientific reviewer | Other

Web of Science ResearcherID: not public

Expertise & keywords

Eco-friendly nanocomposites based on bio-PA and bio-fillers for injected auto parts Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0795 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation:

Project website: https://icechim.ro/project/econano4auto/

Abstract:

The ECONANO4AUTO project offers an innovative and efficient solution for the field of smart specialization - Energy, environment and climate changes, namely reducing the CO2 footprint and accumulations of polymeric waste, by developing of new and innovative technology for obtaining of new polymer bio-nanocomposites based on bio-PA and keratin/ nanoparticle hybrids, lightweight and with improved thermal and mechanical properties. Starting from high-performances bio-PA10,10 and a natural waste (chicken feathers) the project will provide at the end a viable, low cost and eco-friendly solution for effective using of chicken feathers and reducing of impact on environmental pollution. The developed technology will be validated in laboratory conditions to obtain parts by injection moulding. A toxicological study will be carried out regarding the nanomaterials action on the epidermal and pulmonary cells and a methodological guide will be elaborated regarding the prevention of the risks related to the work with nanoparticles. The partnership for this project involves 2 R&D National Institutes, well known in Romania and abroad, competent in the project field and with scientific and technical potential for development and characterization the new technology for obtaining bio-polymer nanocomposites.

Innovative zeolite/graphene stone paper electrodes for pesticides detection in fruits and vegetables Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente - TE-2021
PN-III-P1-1.1-TE-2021-0358 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation:

Project website: https://www.itim-cj.ro/PNCDI/smartsens/

Abstract:

The major scope of this project is to develop and validate a laboratory technology for the detection of pesticides (glyphosate, cymoxanil) in fruits and vegetables samples using a new stone paper sensor based on composite material (zeolites/ graphene-Co nanoparticles) and a portable device coupled with a smartphone. The project proposes a revolutionary, fast and ecological method of obtaining graphene with the electric field created by plasma. The new sensor will be designed, characterized and validated by the young team. The experimental proof of concept will be demonstrated by testing the new flexible electrodes in laboratory solutions containing pesticides to evaluate the electro-analytical characteristics: sensitivity, limit of detection and linear range. The results obtained in real samples of fruits and vegetables will be compared with the results obtained with the chromatographic method. The feasibility of the project is demonstrated by the excellent experience of the Project leader in the area of electrochemical sensors. The main deliverers of the project will be: 3 ISI papers; 4 presentations at conferences; 1 laboratory technology for pesticides detection; 1 patent application. The impact of the present project is going to be high for scientific community and for food safety, public health and quality control of life due to this smart and portable testing device for monitoring the presence of pesticides in food stuffs.

Plasma Lab Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente - TE-2021
PN-III-P1-1.1-TE-2021-0661 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation:

Project website: https://www.itim-cj.ro/PNCDI/plasma-lab/

Abstract:

In this project we are assembling a team of skilled young researchers who together will form the first official plasma lab in our institute (INCDTIM) with the main objective to design and build innovative plasma systems / devices for microorganism inactivation / decontamination, which will serve humanity.

Cold plasma has entered this field as a novel, highly efficient and clean solution for virus inactivation.

Cold atmospheric plasma (also known as open-air nonthermal plasma) operating at atmospheric pressure and almost room temperature (T
Among its complex constituents, the emission of UV radiation and reactive oxygen and nitrogen species have the most important antimicrobial properties.

UV photons damage nucleic acids, whereas the highy reactive molecular species present in the plasma can oxidize the viral nucleic acids, proteins and lipids.

TiO2 nanotubes/graphene-based nanomaterials to address the emerging contaminants pollution Call name: EEA Grants - Proiecte Colaborative de Cercetare
RO-NO-2019-0616 2020 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); University of South-Eastern Norway (NO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA " HORIA HULUBEI " - IFIN - HH (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: https://www.itim-cj.ro/PNCDI/graftid/

Abstract:

For the past century, the environment suffers from rapid deterioration due to the explosive development of chemical and pharmaceutical industries. Large quantities of drugs, personal care products, detergents, pesticides, food additives have been released in the aquatic system. The pollutants of emerging concern are not yet monitored and well regulated by authorities while there is an increased awareness of their impact on human health. The United Nations World Water Development Report 2018 states that “An estimated 80% of all industrial and municipal wastewater is released to the environment without any prior treatment, resulting in a growing deterioration of overall water quality with detrimental impacts on human health and ecosystems”. Advanced Oxidation Processes (AOPs) based on photocatalysis are the most powerful and viable alternative to the conventional wastewater treatment technologies that still have some limitations (e.g., high operation costs, energy consumption, or reduce efficiency due to the chemical stability of pollutants and/or the complexity of their degradation). Thus, the development of solar-driven catalysts with improved photocatalytic activity for the environment-friendly and facile treatment of aquatic systems remains an important target to environment remediation.

Graphene-based stochastic sensors for molecular diagnosis of upper gastro-intestinal cancer Call name: P 4 - Proiecte Complexe de Cercetare de Frontieră
PN-III-P4-ID-PCCF-2016-0006 2018 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA DE MEDICINA, FARMACIE, STIINTE SI TEHNOLOGIE DIN TARGU MURES (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://www.ralucavanstaden.ro/pdf/RAPORT%20FINAL.pdf

Abstract:

The main objective of the project is to design a new generation of stochastic sensors based on modified graphene materials for the fast screening of biological fluids (whole blood, saliva, urine) as well as of tissue samples, in order to diagnose faster the upper gastro-intestinal cancer. In this regard, a panel of biomarkers specific to this type of cancer was selected to be analyzed using stochastic sensors. In the final stage, statistic evaluation of correlation between the panel of biomarkers found in biological fluids and tissue samples using stochastic sensors will be performed, providing the information about the possibility of diagnosis of this cancer without performing the biopsy, all only based on screening tests of biological fluids and complementary imagistic noninvasive techniques. The panel of markers proposed to be analysed is the following: - the marker that is known to be supressed during gastric and gastro-esophageal carcinogenesis - p53, it will be used as a banchmark. The other biomarkers that will be used are the following: maspin, heparanase (an endoglycosidase that is a major component of the extracellular matrix), MMP-2 and MMP-9 (two matrix metaloproteinases), HER-2 and CD26/DPP4 (a surface T cell activation antigen). Graphene materials dopped with nitrogen and boron will be synthesized and use as paste unmodified or modified with fructans, ionic liquids or aptamers for the design of stochastic sensors. The stochastic sensors will be fully characterized electrochemically, and validated against a minimum of 200 real samples from confirmed patients: biological fluids and tumoral tissues will be used for validation, but also for developing of a faster, noninvasive method of screening for fast diagnosis, avoiding in this way the biopsy.

Partnership for the transfer of innovative technologies and advanced materials in the field of visual arts (production, preservation, restoration) Call name:
ID P_40_374 2016 - 2021

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (); CORAMI FUNZIONE SRL (); DUCT SRL (); CENTRUL IT PENTRU STIINTA SI TEHNOLOGIE S.R.L. (); CENTRUL DE COMPETENTA IN ELECTROSTATICA SI ELECTROTEHNOLOGII S.R.L. (); DANART IMPORT EXPORT SRL (); ZAREDARTE SRL (); ARS VITREARUM AMAGA S.R.L. ()

Affiliation: UNIVERSITATEA BABES BOLYAI ()

Project website: http://tematicart.granturi.ubbcluj.ro/

Abstract:

Emerging technologies for the industrial capitalization of 2D structures (graphene and nongraphenic) Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0387 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA DIN CRAIOVA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=49

Abstract:

EMERG2Ind is a complex solution that responds to the needs of Romanian research on one side through a institutional management and development mechanism, but at the same time it is a complex interface tool for the Romanian automotive industry as a development engine and integrator for the horizontal and vertical integration of the Romanian economic resources. International expertise is available in an attempt to develop concrete solutions in the country. Emerging technologies are being developed up to TRL4 and TRL5, through complementary harmonization of three strategic subprojects. The complex project approach is regional and institutional with cumulative indicators that fully meet the requirements and seeks to maximize the use of the funding instrument.

Characterization of the sub-cellular effects of functionalised magnetic nanoparticles in targeted anti-tumor therapy Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-0608 2015 - 2017

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO)

Affiliation: UNIVERSITATEA BABES BOLYAI (RO)

Project website: http://poravpaul.wix.com/cellspion

Abstract:

Having unique magnetic properties, super-paramagnetic nanoparticles (SPIONs) are an efficient vector for anti-tumor targeted therapy, non-viral gene therapy, magnetic resonance imaging contrast agent, and thus personalized medicine. SPIONs are cheap and easy to synthesize, have determined dimensions, can be functionalized and loaded with various substances, and they can transport a certain drug to a certain area of the body in a targeted way, being conducted by magnet. They can be, this way, monitored in real time and at the area of interest SPIONs combine the chemical effect of the drug with the physical effect of the magnetic fluids induced hyperthermia, which generates selectively local overheating through an external magnetic field. In spite of all this promising features, there is still a certain holdback for using SPIONs as a nanotherapy method. This happens mostly because of the fact that nanomedicine is a new domain and because of the lack of coherence in all studies involving NPs in medical applications. Through our project we intend to integrate all aspects regarding cell-NPs interactions and to eliminate all dissonances that shows when passing from a certain study system to another (in vitro-2D-3D-in vivo), finally leading us to obtain coherent data. This is why this study is needed, a complete, integrating and complex study, which starts from NPs synthesis, bioavailability, cytostatic loading, fluorescent loading, in vitro and then in vivo, up to clearance.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects