BrainMap

Alina - Mihaela Popescu

- INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD

Researcher

Curriculum Vitae (11/11/2021)

Expertise & keywords

DEVELOPMENT OF MULTIPLE AND SELECTIVE SENSOR FOR DETECTION OF REPRESENTATIVES EXPLOSIVES Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0474 2014 - 2017

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA (RO); Academia Tehnica Militara (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); MIRA TELECOM S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO)

Project website: http://sensorex.incemc.ro/

Abstract:

Globalization of terrorism became a reality that can not be disputed, a threat to national and international security and, thus, a phenomenon under the responsibility of the entire international community. Terrorist threat, theatres of operations with explosive traps everywhere, with the possibility of using biological weapons of various viruses, drugs, etc are a constant threat to the civilian population, unwittingly victim of varied interests. It is an ongoing concern of many laboratories in the world to detect traces of explosives in the atmosphere, in order to minimize the risks arising from them. To avoid or prevent serious incidents that could endanger people's lives, EU adopted new security rules. These rules apply to security checkpoints at airports, the senior public institutions, in the cultural and artistic events with massive participation, etc. However, there are situations in which all efforts to prevent terrorist acts are not sufficiently effective, creating holes that are exploited by potential attackers. Therefore, rapid detection of explosive compounds is of great interest given the need to prevent any human casualties and material damages caused by their use in different ways and for destructive purposes. The principle SENSOREX will bring an additional performance in the field of detection devices for dangerous substances with the low response time, high specificity, greater functionality and last but not least a low production price. Practical relevance of the project subject is to develop innovative products and manufacturing processes that underlie the development of sensitive, selective, reliable and low cost sensors detection of explosives. Appearance is very important from the perspective of efficient procedures for prevention of terrorism threats by using them in areas where existing equipment besides being very expensive, are almost impossible to use due to ergonomic aspects, reducing processing time suspicious persons and packages various strategic points and last but not least reduce additional costs. The main objective of SENSOREX project is to develop through this national partnership, a sensor with high sensitivity detection of explosives traces . Implementation status of this sensitive platform will be a sensor – demonstrator model tested and calibrated with low response time, high sensitivity and specificity, easy to use and interpreted by a non-specialist user and not least a low cost. Progresses that SENSOREX project brings through its results are: innovative methodologies for obtaining titanium dioxide films and molecularly imprinted polymers; creating scientific premises for serial production of a device with high sensitivity to reduce the most important barriers to personal and group security; final product of the project, sensor – demonstrator model, by its future implementation in production strategy of the private company, partner in this project, it will cover a hole on external and internal market of the profile products.

Immunoassay Lab-on-a-chip for cellular apoptosis study Call name: Joint Applied Research Projects - PCCA-2011 call, Type 1
PN-II-PT-PCCA-2011-3.1-0052 2012 - 2016

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO); UNIVERSITATEA TRANSILVANIA BRASOV (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO)

Project website: http://www.imt.ro/cellimmunochip

Abstract:

The ambitious goal of this project is to combine fundamental research with complex applicative research in order to bring important scientific contributions both on the theoretical level and on the experimental one, in a high-end field: bio-nano-engineering, a new field in Romania and in expansion stage worldwide. Bio-nano-engineering assumes the integration of the physico-chemical processes with the biological ones by involving complex systems realized on the micro or nano scale, the applications of these systems being found in biomedicine The aim of this project is the development (design, fabrication and characterisation) of a versatile lab-on-a-chip integrated system, which is composed of a microfluidic platform, an interdigitated micro/nano-electrodes electrochemical biosensor and an array of spin valves for superparamagnetic nanoparticles - based immunoassay, and will be applied to the study of cellular apoptosis and detection of specific antigens as clinical diagnostics application. The screening reaction is based on a competitive immunoassay, enhanced by using functionalized superparamagnetic nanoparticles, prepared through a simple and reliable surface modification and protein conjugation process. The main advantage of this system is its re-usability. Also, its configuration can be changed easily so the user can try several electrode configurations with the same holder. Moreover, because the functionalized nanoparticles are magnetically trapped above the electrodes, the user can adjust the fluid flow rate to the kinetic parameters of chemical reactions under study to optimize detection. The superparamagnetic nanoparticles can be trapped by polarization of the spin valve array and can be released by blocking the magnetic field. We shall demonstrate how to take further advantage of the microfluidic system to determine enzyme activities or concentrations, as flow velocity can be adjusted to the rate of the reactions under study.

Active micro-shields systems for protection of space infrastructures Call name:
2012 - 2014

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO)

Project website:

Abstract:

Microfluidic Factory for Assisted Self-Assembly of Nanosystems Call name:
POSCCE/665/12609/209/20.07.2010, 2010-2015 2010 - 2014

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD ()

Affiliation:

Project website: http://www.imt.ro/MICRONANOFAB/index.php

Abstract:

Nanosystems employed to deliver active solutions (drugs) or genes only in specific cells or tissuesfor bio-imaging are, without doubt, of great importance for diagnosis and treatment of different

pathologies and can become feasible from the economic point of view. The encapsulation will be performed by self-assembly of nanosystems in microfluidic channels by employing the use of liposomes.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator
List of research grants as partner team leader
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects