BrainMap

Mrs. Alina Ortan

DR

ASSOC. PROF. - UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA

Researcher | Teaching staff | Scientific reviewer

Web of Science ResearcherID: SCOPUS ID 35146234600

Curriculum Vitae (15/05/2024)

Expertise & keywords

TRANSDISCIPLINARY APPROACH FOR DEVELOPMENT OF TECHNOLOGICAL SOLUTIONS FOR TARGET COMPOUNDS RECOVERY FROM AGRO SIDE-STREAMS Call name: P 3 - SP 3.5 - Proiecte EUREKA Tradiţional (Network), EUREKA-Cluster, Eurostars
PN-III-P3-3.5-EUK-2019-0226 2020 - 2023

Role in this project: Partner team leader

Coordinating institution: HOFIGAL EXPORT IMPORT SA

Project partners: HOFIGAL EXPORT IMPORT SA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Affiliation:

Project website: https://hofigal.eu/content/26-proiect-tardis-hofigal

Abstract:

The project TARDIS is proposed in the context of closing chains in bioeconomy, in order to obtain extracts with increased target bioactive content, with potential pharmaceutical applications (Pharmacoidea) and/or nutraceutical products (HOFIGAL). Biowaste valorisation is an attractive approach in the framework of the EU Waste Management policies and the development of a circular economy. Wastes from biostreams and different bio-based sources are being under-utilized as potential resource of valuable compounds.

The general objective of the project is to underline, optimize and apply an integrate technology of sustainable and enhanced production of natural extracts with high content of biological active compounds from side streams of agricultural industries applicable for obtaining smart formulations for disorders of the 21st century, for which continuous research is carried out.

The main idea of the project is to process plants by-products rich in nutritional and bioactive compounds into formulations to be used in pharma industry with the following benefits: the use of obtained extracts and target compounds for the prevention / treatment of age-related neurodegenerative disorders such as Alzheimer's disease; minimizing the amount of plant waste by recovering the target compounds from the by-products; increasing the potential of the pharmaceutical and food market by designing new functional ingredients; increasing the quality of life.

The project will provide the necessary support for creating and developing a complementary research chain in bio-economy (industry, pharmacy, agriculture) that aims to achieve a high level of internationally recognized expertise. The project demonstrates an integrated cascading concept including pre-treatment, optimized extraction and separation technologies.

Comprehensive Approach to support Precision Agriculture and environmental management through satellite technologies and classic methods of investigation Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3495 2020 - 2022

Role in this project: Partner team leader

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: http://environment.inoe.ro/article/253/about-capa

Abstract:

The project ‘Comprehensive Approach to support Precision Agriculture and environmental management through satellite technologies and classic methods of investigation – CAPA’, addresses a major direction of the 21st century, namely, smart agriculture, bringing new insights into how the climate affects the phenological cycle of crops (through the occurrence of extreme events) and it also contributes to understanding the role of different air pollutants (such as greenhouse gases) in crop development. The project proposes the realization of synergies of the scientific activities integrating data on the complex eco-agro-system-culture relations, obtained by applying a conglomerate of methods and techniques (space technologies, the study of pollutants at the level of air, water, soil and plants), for a modern management of agricultural crops, in the context of intelligent agriculture. At the international level, smart agriculture is also based on the optimized management of the inputs according to the real needs of the crops, for their management and the reduction of the use of fertilizers, fungicides, pesticides and water resources. At the national level, the exploitation of satellite records in the field of agricultural management has not yet a significant spread, being used mainly in applications dedicated to environmental protection, forestry, territorial planning or in the military field. In this context, the project proposes the application and integration of spatial technologies together with in situ and ex situ analyses in the intelligent management of agriculture to monitor certain types of agricultural crops (from a pilot site), thus allowing the development of a successful model for better capitalization. of available resources.

Green technology for pharmaceuticals removal from water using eco-friendly oxidation catalysts Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3166 2020 - 2022

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); I.C.P.E. BISTRITA S.A. (RO)

Affiliation: UNIVERSITATEA BUCURESTI (RO)

Project website: https://www.avramescu-sorin-marius.eu/greencatox/#

Abstract:

Catalytic ozonation is a highly efficient process for removing most resistant organic pollutants from water and is a key process in wastewater treatment. Improving these technology in order to comply with green chemistry challenges is an important goal purification industry. Catalysts are the core of the process and, in the last decade, numerous studies and patents proposed a large range of materials for better ozone transformation into hydroxyl radicals and performing complete oxidation of the organic substrate. This project proposes a new and innovative class of ozonation catalysts with a morphology that assures an easy contact of ozone and pollutants with solid surface (thin-films) and green and cheaper technology for catalyst preparation using plant extracts instead of harmful chemical reagents (borohydride and organic solvents)

Multidisciplinary complex project for the monitoring, conservation, protection and promotion of the Romanian cultural heritage Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0413 2018 - 2021

Role in this project: Key expert

Coordinating institution: AGENTIA SPATIALA ROMANA

Project partners: AGENTIA SPATIALA ROMANA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); MUZEUL NATIONAL AL UNIRII ALBA IULIA (RO); MUZEUL CIVILIZATIEI DACICE SI ROMANE (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: http://ro-cher.rosa.ro

Abstract:

The Cultural Heritage (CH) can represent one of the decisive factors for the standard of living and for the quality of life specific of different communities, can contribute to the prevention of cultural globalization, can support the cultural diversity and can positively influence the economic development. The protection of the CH represents a major concern for decision-makers, local communities and European citizens. At the European Union level, the year 2018 has been declared The European Year of Cultural Heritage. In the same time, Romania faces a very important historical celebration: The Centenary of the Great Union from 1918. The RO-CHER project proposes a multi-disciplinary innovative methodology that integrates high level scientific knowledge for safeguarding the cultural heritage and that targets the development of synergetic scientific activities in the framework of the 4 complementary component projects by: monitoring the CH objectives with the aid of space technologies; development of materials and innovative techniques based on soft nanomaterials for safeguarding the cultural heritage; recommendation of an integrated management system (conservation, restauration, protection) for mobile and immobile CH objectives; promoting CH by using state-of-the-art technologies of digital reconstruction. The specific results indicators, predicted since the pre-implementation phase, are: new jobs in research (7); patent requests (6); results validation and transfer to the economic environment; design and development of the services offer and the research infrastructure; mutual access of partners at equipments and technology; institutional capacity building by internships/training sessions and working visits; joint R&D&I programme, correlated with the development strategy of each partner, all of these leading to the creation of a knowledge cluster, being able to successfully access national and international funding.

Development of smart and low energy input processing chains, natural food additives and colourants, and supportive material for a code of practice to increase sustainability and consumer acceptance of organic food stuffs Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-COREORGANIC-SusOrgPlus 2018 - 2021

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA

Project partners: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: https://www.usamv.ro/index.php/ro/696-susorgplus

Abstract:

Organic food processing is characterised by empirical approaches resulting in high specific raw material and energy demands as well as product deterioration, thus, impacting on overall sustainability and product quality. Steps towards mitigation have been taken (Core Organic Plus), but there is still a lack of a clear Code of Practice.

Restrictions in the usage of additives and the need of phasing out contentious materials further increase pressure whilst the full potential of natural additives and colourants is not explored. SusOrgPlus will address these issues for the processing and production of value added products of selected plant and animal origin products through the development of novel, smart processes, natural additives/colourants and supporting material for a Code of Practice. Inclusion of leading food scientists, process, mechanical and control engineers, agriculturalist and a technology provider and utilisation of a stakeholder guided approach will assure all aspects relevant for the development of smart, efficient and low energy input processes and value added products. The geographical balance, with participants from Central, Eastern, Northern and Southern Europe, will assure the relevance of the project across the EU and beyond.

USAMV Bucharest's contribution to the objectives of the SusOrgPlus project will provide to the ecological sector: (a) value-added products (natural additives/colourants); (b) increasing the processing technology efficiency, reducing specific consumption of bio-resources; (c) reduction of direct waste resulting from the processing of fresh raw material; (d) quality and sensory assessment of the innovative organic products obtained; (f) analyzing the acceptability of consumers for organic food enriched with food additives and natural dyes; (g) supportive material for a code of practice; (h) dissemination of project results and training of farmers/processors, other stakeholders involved in education and research (students, master students, PhD students, teachers, researchers, etc.).

SUSTAINABLE VALORIZATION OF BY-PRODUCTS FROM MEDICINAL AND AROMATIC PLANTS INDUSTRY INTO VALUE-ADDED PRODUCTS Call name:
POC 89/09.09.2016; SMIS 104323 2016 - 2020

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA

Project partners: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA ()

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA ()

Project website:

Abstract:

The main objective of SuSMAPWaste project is the development of green technologies for obtaining a fibrous support material from oleaginous plants waste, enriched with a penta-component formula with multi-target effect (antioxidant, probiotic and detoxifying) from medicinal and aromatic plants waste, for human consumption. The project is going to develop tools, methodologies and processes for the valorization of wastes through an integrated bio approach, using advanced biotechnological methods.

Innovative ferrite/beta-cyclodextrin core-shell nanocomposites for removal of inorganic and organic pollutants from aqueous effluents Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0251 2017 - 2018

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: UNIVERSITATEA BUCURESTI (RO)

Project website: http://www.unibuc.ro/prof/avramescu_s_m/NanoFerDeX.php

Abstract:

Adsorption process is effective in removing certain organics but a large part of inorganic and organic pollutants cannot be removed using existing adsorbents Nanotechnology is an enabling technology that can help address key needs relating to energy, environment, health and agriculture all over the world.

This project proposes a new and innovative class of nanoadsorbents with core–shell morphology. These nanoadsorbents will be made from ferrite particles (core) and cyclodextrin moieties (shell) in order to benefit from outstanding properties of both materials: magnetic properties of ferrites nanoparticles and high adsorption capacity of cyclodextrin molecules. These nanoadsorbents will be used in treatment of wastewaters containing organic and inorganic pollutants. After thorough assessment of operational parameters at laboratory scale the prepared core-shell adsorbents will be tested at pilot scale in order to confirm, through their physical-structural and chemical properties the utility of these materials in water treatment processes.

Core COPERNICUS infrastructure for a national geospatial advisory system for irrigated perimeters Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1506 2014 - 2017

Role in this project:

Coordinating institution: AGENTIA SPATIALA ROMANA

Project partners: AGENTIA SPATIALA ROMANA (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); UTI GRUP S.A. (RO); TRADSYM CONSULT SRL (RO); INSTITUTUL DE ECONOMIE AGRARA - INCE (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: http://geofarm.rosa.ro

Abstract:

The integration process between agriculture and environment promotes the development of agricultural practices that preserves the nature and the rural heritage (landscape and traditional life of people). EU directives (Water Framework or Nitrates) and the Rural Development Program define objectives and indicators to evaluate the agro-environmental impact of farm practices. The commercial goal to maximize returns and minimize costs increased the role of agro-technology, which is limited by the local resources.

As business, agriculture aims at production (maximize returns and minimize costs) and depends on the availability of local natural resources (water and soil) by exploiting this found. For growing the production, it is necessary to implement a modern approach based on exogenous data, as satellite imagery, integrated in a thematic GIS, for evaluating the real need in water and fertilizers at parcel level. Based on these considerations, the European COPERNICUS/GMES-Global Monitoring for Environment and Security- initiative aims the development of EO based public services able to create benefit for the agricultural sector. EC transferred at member state level the responsibility to develop and sustain at national locally adapted COPERNICUS services. GEOFARM will contribute to the development of the Romanian agricultural sector (affected by the land redistribution process generating an unstructured rural landscape).

The implementation of a service for farmers needs efforts for disseminate the knowledge in view of implementing the research results, taking into account the specific landscape/ environment and socio- economic contexts. Such a solution needs an important scientific investment and a multi-disciplinary approach.

This service will be developing in terms of integrating the technological tool within farming practices. It has to be optimized according to the diversified local farm typologies (described by the size of parcels, number and quality of equipments, orientation of the production), the environmental limitations (soil, climate, water source) and tacking into account the socio economic conditions which suffered significant negative evolutions and changes during the past 20 years.

The synergic analysis through satellite images and agro-models (as support for the sustainable management of farms) will allow the end-user to determine an optimal input for each affected area inside the plot, according to intra-parcel variability, by accessing a secured web interface, for visualize and locate the vulnerable areas.

The GEOFARM service has to be considering as a complementary advanced approach to already concluded FP 6 (PLEIADeS) or ongoing FP 7 (SIRIUS) COPERNICUS Core Services projects.

INNOVATIVE THERAPEUTIC PRODUCTS WITH PROPHILACTIC AND CURATIVE ACTION FOR ZOO-VETERINARY SECTOR Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0953 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA

Project partners: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); ASOCIATIA CENTRU DE CERCETARE STIINTIFICA IN DOMENIUL BIOCHIMIEI APLICATE SI BIOTEHNOLOGIEI (BIOTEHNOL) (RO); BIOING S.A. (RO); HOFIGAL EXPORT IMPORT SA (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: http://sanovet.fifim.ro/

Abstract:

Title: „INNOVATIVE THERAPEUTIC PRODUCTS WITH PROPHILACTIC AND CURATIVE ACTION FOR ZOO-VETERINARY SECTOR”

Acronym: SANOVET

Program: PARTNERSHIPS

Subprogram: “ Applied Collaborative Research Projects”

Domain 5 - Agriculture, food safety and security

Research thematic: 5.1.4. Methods, techniques and technologies for growth and diversification of animal production and fisheries, veterinary protection insurance Animal health is a concern for all European citizens. This concern stems from the public health, food safety and food security aspects, which are related to animal health but also to economic costs that animal disease outbreaks can trigger. This project uses a very common and a high economical and ecologically impact disease model like inflammation, as a paradigm for a conceptual and practical approach aimed to capitalize inexpensive and available resources.

The project goal is to improve the level of veterinary protection by developing a semi - solid phytoproduct from indigenous flora with topical application.

Main objectives that will ensure the achievement of project aim are:

1. Obtaining crops to exploit the curative potential of Anthriscus sp.;

2. Obtaining the phytocomplex;

3. Evaluating extracts pharmacological viability;

4. Obtaining an innovative phytoproduct .

The results of this research project will be materialized through:

1. Development and characterization of a herbal extract enriched in active ingredients with a complex chemical structure, non-toxic, based on original recipe obtained from association of fractionated extract with volatile oil from Anethum sp properly processed,

2. Highlighting the biologic activity, which plays a role in sustaining and accelerating the healing process by in vivo testing of herbal extract,

3. Creating a new topic semisolid phytoproduct.

The project addresses to a major agricultural problem in an interdisciplinary aggregate approach in order to achieve high yields results with a low economical input and a great environmental safety.

Innovative drugs with high therapeutic potential from vegetable resources Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-1000 2012 - 2016

Role in this project:

Coordinating institution: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA

Project partners: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); SLAVIA PHARM S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU ECOLOGIE INDUSTRIALA - ECOIND (RO)

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Project website: http://www.biotehnologii.usamv.ro/articole/123-proiect-sqmedi

Abstract:

Natural products – including bio-active extracts that could be isolated from various vegetal sourses – may constitude the basis of many safety drugs. By this project, it intended to develop some innovative technology to obtain bio-active oils enriched in squalene from Roumanian vegetable sources – Amaranthus sp. and pumpkin (Cucurbita sp. seeds) (first objective) and to use them for developing some innovative nanostructured products with beneficial health properties. The exploitation of vegetable sources for obtaining various lipid nanoparticles derived from natural bio-active lipid oils enriched in squalene, represents a highly innovative research which has never been previously used in the nanotechnology field for some drug delivery and targeting purposes.

The ability to combine the bio-medical properties of developed vegetable oils with the unique properties of nanoparticles will be demonstrated in the frame of second project objective. Some bio-active lipid nanoparticles derived from intermediary bio-active oil fractions and/or natural squalene concentrates (>90%) will be applied as efficiently carriers for delivery and controlled release of two kinds of toxically/synthetic drugs (one antitumor drug and two synthetic sunscreens).

The third objective – development of new nanostructured bio-pharmaceutical products based on highly reproducible lipid nanoparticles derived from vegetal squalene oils – has the main purpose to the conditioning the obtained nanoparticles as solid and semisolid pharmaceutical formulations in order to develop innovative drugs with multiple bio-medical activities. In this respect, some in vitro and in vivo specific experiments (e.g. antioxidant, photo-protective, wound-healing and antitumoral) will be conducted for demonstrating their superior therapeutic performance.

Based on the results obtained from the previous objective and having in view the economical aspects, the final objective – demonstration of functionality of the experimental models, efficacy of the vegetable bio-products obtained, innovative drugs developed and the methods of analysis – will be accomplish by developing industrial batch “0”, meaning 3 or 4 new drugs that will be introduced for commercialization on the Romanian market.

Studies concerning the obtaining of transdermal hormonal systems using the lyposomes as transport and drug controlled release vectors Call name:
61-024/2007 2007 - 2010

Role in this project: Partner team leader

Coordinating institution: UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"

Project partners: UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (); PHARMA SERV INTERNATIONAL SRL ()

Affiliation: UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA ()

Project website:

Abstract:

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects