BrainMap

Mr. Bogdan Trica

Dr. Eng.

Scientific Researcher - Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Researcher

Curriculum Vitae (11/10/2019)

Expertise & keywords

INNOVATIVE FULLERENOL - HYDROGELS BASED NANOMATERIALS FOR HEALTH DIAGNOSTIC AND CARE APPLICATIONS Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-M-ERANET-3-FULSENS-GEL 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CHIMGRUP S.R.L. (RO); Ordu University (TR); Metrohm Dropsens, S.L. (ES)

Affiliation:

Project website: https://www.fulsens-gel.ro/

Abstract:

The project aims to develop an innovative nanomaterial with tunable network structures and improved electrochemical/ mechanical/ optical properties, with active surface for sensing applications. The innovative objectives aims to develop: a) new fullerenol(FL)-Hydrogel nanomaterials with better functionality and opto-electrochemical performances; b) (bio)sensitive FL-Hydrogels with higher stability, selectivity and sensitivity; c) flexible, wearable FL-Hydrogels multiplex patches for rapid and efficient health status screening.

Prototype coating system to reduce the CO2 footprint and environmental impact in shipping Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0675 2022 - 2024

Role in this project:

Coordinating institution: QWERTY DEVELOPMENT MACADA-M S.R.L.

Project partners: QWERTY DEVELOPMENT MACADA-M S.R.L. (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://sparacom.ro/rezultate/ si https://sparacom.ro/date-generale/

Abstract:

SPARACOM is a complex solution for the transfer to the economic operator, in order to increase the competitiveness of the economic environment and the assimilation of market-oriented RDI results. The consortium involves the collaboration between an innovative company and a large research institute in the field. The proposal aims at the efficient maximization of the financing instrument (technological maturation of TRL4 to TRL6; it starts from the technology validated within PN-III-P2-2.1-PED-2016-1332, 84PED, financed by UEFISCDI; the use of an infrastructure at international level; SMEs with high innovative potential; avant-garde technological solution, an opportunity at the level of the international market; connecting national applied research to the national and international market). The budget is balanced by allowing adequate and flexible resources for better management and contingency plans. To maximize the final results some activities and budgetary resources from outside the project are committed to increase the visibility and impact of research. The CO and P1 research team implies an important institutional character: members from several departments and research teams together with the valorization of competencies. The technological approach involves advanced hybrid antifouling systems (and acting in a sequential mode) but also a self-repair system with potential in freshwater and marine environments (a major challenge in the field). The expected results involve both TRL technology and at least: a paper at scientific events, a paper sent for publication to an ISI publication, a patent application, a web page.

BIOGENIC AMINES DETECTION IN FOOD BASED ON AN INNOVATIVE OPTO-ELECTROSENSITIVE PLATFORM Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-1942 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); EPI-SISTEM S.R.L. (RO)

Affiliation:

Project website: https://ami-food.ro

Abstract:

The AMI-FOOD project aims to develop cost-effective and robust miniaturized opto-electrosensitive platforms based on an innovative fullerenol (FL) nanomaterial, with enhanced electrochemical, optical and mechanical properties, for specific and sensitive determination of biogenic amines (BAs) in food. The specific objectives of the project are: To develop a novel FL nanomaterial with tailored structure and enhanced functionality, electrochemical and optical properties; To develop bioselective layers based on FL and specific aptamers, with higher stability, selectivity and sensitivity for histamine and histidine determination; To develop miniaturized opto-electrosensitive bioanalytical tools for rapid and efficient screening of BAs in food. The integrated opto-electrosensitive platforms equipped with novel nanostructured FL material and specific aptamers will show higher sensitivity, specificity and stability comparing to existing commercial ones, responding to the urgent need of a tool for food quality monitoring and controlling of food spoilage/degradation in real time. The originality of this project consists in the design of new versatile (apta)sensors based on the synergistic combination of FL and luminescent based nanomaterials with specific aptamers. The outcomes of AMI-FOOD project are: (i) Innovative functionalized FL nanomaterials; (ii) highly sensitive and selective biosensing materials based on FL and aptamers; (iii) Prototype of opto-electrosensitive platforms based on FL and aptamers for BAs determination in food (TRL4) and (iv) Optimized method for BAs detection in food by using the developed FL-aptamer based bioanalytical tools. This project will have a high socio-economic impact on the safety food and health quality, contributing to reducing and eliminating the contaminated food from the market.

Foliar fertilizers with increased effectiveness Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0414 2022 - 2024

Role in this project:

Coordinating institution: AGSIRA SRL

Project partners: AGSIRA SRL (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU PEDOLOGIE, AGROCHIMIE SI PROTECTIA MEDIULUI - ICPA BUCURESTI (RO)

Affiliation:

Project website: https://agsira.ro/fertilizanti-foliari-cu-eficacitate-crescuta/

Abstract:

The aim of the project is to increase the competitiveness of the coordinating company, Agsira SRL, and of the farmers using high efficiency fertilizers proposed by the project, by assimilating a RDI result in the field of circular bioeconomy.

The high efficiency fertilizers proposed by this project are in the category of liquid fertilizers, which are applied as a treatment for the aerial parts of plants, by spraying. The novelty is that these fertilizers include brewer's yeast walls with multiple roles: formulation agent (surfactant, moisturizer and foliar adhesive), chelating for mineral oligo- and micro-nutrients and biostimulant for plants.

The objectives of the project are: (i) the development of a pilot plant for the production of high efficiency foliar fertilizers; (ii) validation of pilot technology for the production of high efficiency fertilizers in an industrial environment; (iii) demonstration of the functionality of the technology in the industrial environment by characterizing and testing high efficiency fertilizers.

The main innovative aspect is the use of yeast cell walls as a multifunctional ingredient, formulation agent (surfactant, moisturizer and foliar adhesive), chelating for oligo- and micro-nutrients and biostimulant for plants. Another innovative aspect is the use of a second generation biostimulant, which includes exo-signals for crop plants. Through the proposed project we intend to validate and demonstrate in the industrial environment the fertilizer manufacturing technology using this second generation of plant biostimulants, concentrated exo-signals from the category of elicitors produced from yeast cell wall, which are combined with mannoproteins, formulation agent and chelating.

Ecotechnology for obtaining phytoingredients encapsulated in hydrogel based on bioactive complexes immobilized in a layer double hydroxide matrix Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-1870 2022 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CENTRUL DE CERCETARE SI PRELUCRARE A PLANTELOR MEDICINALE PLANTAVOREL SA (RO)

Affiliation:

Project website: https://www.chimie.unibuc.ro/cercetare/cataliza/PN-III-P2-2_1-PED-2021-1870/DUACTIVMER.pdf

Abstract:

The project aims the development of integrated validated eco-technologies (TRL4) with double action: 1) obtaining hydrogel encapsulated bioactive ingredients based on phytocomplexes from 2 medicinal plants (e.g. Rhamnus frangula L (RfL) and Helianthus tuberosus L (HtL)) with increased biocompatibility and protected from degradation by immobilization in a layer double hydroxide (LDH) matrix, and 2) valorization of spent vegetal after extraction as cheap adsorbent of pollutants from wastewaters. The basic concept of the technology (TRL2) lays on preliminary results obtained by consortium partners in: i) extraction of RfL and HtL phytocomplexes; ii) immobilization of different organic anions in Mg/Al-LDH and Zn/Al-LDH matrices, iii) obtaining of hybrid hydrogels containing bioactive phytoextracts from Rosa Canina and Hypericum Perforatum L immobilized in natural zeolite and iv) treatment of wastewaters polluted with heavy metals and organic pollutants. This project extends the application of double-protected bioactive phytoextracts to new systems based on RfL and HtL phytoextracts incorporated in Mg,Ca/Al,Fe-LDH matrices and further encapsulated into hydrogels. The integrated technology ensuring minimum waste production, will allow the further utilization of obtained active ingrediends in food supplements with benefic effects for improving a lazy intestinal transit due to a constant low apport of glucofrangulins brought by RfL along with electrolytes such as Mg/Ca and Fe, while acting also as prebiotic and promoter of mineral absorption and cholesterol-lowering due to HtL. A benefit for wastewater treatment would also be brought. The use of the obtained products in food supplements could be benefic to people well-being, by reducing the negative effects of their chaotic lifestyle, with too many working hours, continuous stress and most important, poor dietary decisions, all leading to tremendous repercussions on the health of the digestive system.

Strigolactone mimics as the active ingredient of a multifunctional plant biostimulant Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-2866 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO); ENPRO SOCTECH COM SRL (RO)

Affiliation:

Project website: https://icechim.ro/project/rhizostim/

Abstract:

The RhizoSTIM project aims to develop a multifunctional next-generation plant biostimulant product based on strigolactones mimics. This product will act both as a modulator of the rhizomicrobiome and as a regulator of plant response to stress. Strigolactones (SL) are both in-planta and ex-planta signals. These compounds are plant hormones, endogenous molecules that regulate plant response to stress, ecomones/semiochemicals, and exogenous signals involved in plants communication in the rhizosphere. The project objectives are: (i) to design and to develop new strigolactones mimics acting on rhizosphere microorganisms and on plant internal regulating cascade; (ii) to understand the effect of strigolactones mimics on rhizosphere microorganisms and model plants (iii) to test the strigolactone mimics on model systems. The expected results of the project are: (i) QSAR / SAR analysis of SLs mimics by predicting their biological activity as plant biostimulants, useful to guide the synthesis of the new strigolactone mimics; (ii) new chemically synthesized SL mimics, (iii) selected SL mimics with specific activities on beneficial microorganisms from the rhizosphere, others than AMF fungi, substantiated by (iv) in silico identification of the strigolactones putative receptors from rhizosphere microorganisms; (v) demonstration of strigolactone mimics effects on plant and rhizosphere microorganisms which should substantiate the claims for a (vi) multifunctional next-generation plant biostimulant. The RhizoStim project main novelties are related to: (i) synthesis of SL mimics according to a QSAR / SAR analysis, (putative) fungal receptor identification, and atom economy concept, and (ii) multifunctionality, related to effects on plant internal regulating cascade and to effects on microorganisms from the rhizosphere.

Synthetic nanogel antibodies molecularly imprinted with the Spike S1 protein Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente - TE-2021
PN-III-P1-1.1-TE-2021-1239 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://icechim.ro/project/antispike-ro

Abstract:

SARS-CoV-2 is a new coronavirus type and it is responsible for causing COVID 2019 in humans, with very high contagion rate all over the world. The viral entry of SARS-CoV-2 is conferred by the presence of Spike S1 protein on the surface that can direct attachment and enter the plasma membrane of the human cell. The Spike protein through its location is a significant therapeutic target, and targetable using antibodies. Despite recent technological developments, effective and safe therapies are currently not available for treating the infected victims. Thereby, the general objective of the project targets the synthesis of synthetic nanogel antibodies molecularly imprinted with Spike S1 (MIP-SNAs) for recognizing and retaining coronavirus-originated Spike S1 proteins. In this respect, the MIP-SNAs are able to recognize and bond to the Spike S1 proteins, acting as nanogel caps, and thus inhibiting the activity of SARS-CoV-2 antigen to penetrate the human cells. Hence, ANTISPIKE holds significant influence upon the scientific community by new concepts and methodologies for ligand-free delivery systems as MIP-SNAs (short-term impact: scientific ISI papers and communications, and national patent claim) and by opening new research directions associated with the side-benefits of the research (like new immuno-therapies) as long term impact. Implementation of this project will also bring specific scientific, economic and social benefits at the national and international level.

Integrated use of the next generation plant biostimulants for an enhanced sustainability of field vegetable high residue farming systems Call name: EEA Grants - Proiecte Colaborative de Cercetare
RO-NO-2019-0540 2020 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); Norwegian Institute for Water Research (NO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); Norgenotech AS (NO); ENPRO SOCTECH COM SRL (RO); AMIA INTERNATIONAL IMPORT EXPORT S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim.ro/project/stim4plus-en/

Abstract:

The project addresses mainly the thematic area of Biotechnology, more exactly the key topic Biotechnology for agriculture, aquaculture, forestry and biomass production. The biotechnological solutions which STIM4+ project proposes to develop are intended to compensate the negative effects of the low-input, high-residue sustainable vegetable production systems. These proposed biotechnological solutions are related to the use of the next generation plant biostimulants. Plant biostimulants represent an emerging class of agricultural input, which protect plants against abiotic stress, enhance / benefits nutrients uptake and improve yield quality . The proposed plant biostimulants to be used for an enhanced sustainability of field vegetables grown in a high residue system are including into all classes / subclasses mentioned in the new EU Regulation 1009/2019. The multi-functional Trichoderma strains-based plant biostimulants (a microbial plant biostimulants) will be included into a glycodinameric, chitosan based bioactive (micro)hydrogel formulation. Decoration of microgels with anchor peptides will be used as a (micro)hydrogel tackifier on the plant residues. The bioactive hydrogel is based on an organic plant biostimulants (chitosan), which will be used to generate a biocompatible 3D porous structure, thermo- and pH-responsive and with a hydrophilic – hydrophobic segregation feature. This hydrophilic – hydrophobic segregation (micro)hydrogels will be used for embedding hydrophobic mimetic strigolactones. Propper application technologies of such smart formulated hydrophobic molecules will be developed, to exploit strigolactones both functions, as exo-signals for a better harnessing of beneficial microbiome and as cue for deleterious organisms (e.g. to induce suicidal germination of parasitic plants). The smart formulated bioproducts / agricultural inputs and the agricultural practices intended to exploit their specific features of such bioproducts are an example of biotechnologies for agriculture. The natural strigolactones mimics will be a part of the microbial standardized extract, which we intend to produce from microalgae culture and which is another example of organic plant biostimulant. This microbial standardized extract will include natural strigolactones, polyamines and betaines. Both strigolactones and polyamines are exo- and endo-signals. As exo-signals, both strigolactones and polyamines have been demonstrated to enhance mycorrhizae hyphal branching and root colonization. As endo-signals, both strigolactones and polyamines are involved in plant stress responses. Betaine also supports plant response to stress, especially to drought. Strigolactone mimics used for laboratory screening will be synthetized based on a rational bio-design. The inorganic plant biostimulants are represented by selenium, as zerovalent nano-selenium. A large body of evidence demonstrates that selenium acts as a plant biostimulant. Selenium protects plants against abiotic stress, especially drought, enhances / benefits nutrient uptake and improves edible yield quality. Nanoselenium (zerovalent) particles show a much lower environmental impact and an improved efficiency compared to other selenium species. Application of selenium nanoparticles reduces the risk of accumulation of polyamines in the edible yield. From a food safety point-of-view, accumulation of polyamines in vegetables grown into HV mulch could have some carcinogenic effects, because polyamines were found to support proliferation of various tumor cells.

The project is an interdisciplinary one and address also other key topics as Environmental impact and risk assessment of the modern, new and emerging technologies and products. Safety and environmental impact of the new developed products will be determined by a state-of-art 3R techniques, by Norway partners. The project contributes to the objectives and the priorities of the call. It supports research cooperation between Romania and Norway and consolidate a strategic partnership.

Better harnessing of Trichoderma biotechnological potential for biorefinery and as plant biostimulants by controlled development and biosynthesis Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-2780 2021 - 2023

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://icechim.ro/total

Abstract:

Project TOTAL aims to investigate and integrate abiotic modulation and epigenetic control of Trichoderma strains within the context of Trichoderma interactions with biomass and living matter, for better harnessing of Trichoderma biotechnological potential. The specific objectives of the project are: (i) To establish and optimize the combined effects of light and nutrients on expression of proteins acting on plant cell walls and spore formation by Trichoderma strains; (ii) To optimize the deconstruction of plant cell walls by Trichoderma secreted proteins; (iii) To synergize the plant biostimulants effects of Trichoderma chlamydospores. The current approaches targeted the optimization of Trichoderma utilization either in agriculture or in biorefinery. The optimization of culture conditions have been in general focused either on improving sporulation to be used in biopesticides formulations or on the enzyme production for biomass deconstruction. Secondary products have been usually disregarded and discarded. An integrative technology to benefit from both advantages that Trichoderma offers has not been established. We plan to integrate the investigation of the fundamental aspects of Trichoderma development (light-, nutrient- and stress- mediated chlamydospore formation; cell signaling pathways; epigenetic effects) with its growth optimization for the use in both biomass valorization and plant biostimulant formulations.

MANUFACTURING OF A PORTABLE SYSTEM FOR NITRITE MONITORING IN SOIL BASED ON AN INNOVATIVE SENSOR Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-MANUNET-NITRISENS 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); ECONIRV SRL (RO); EPI-SISTEM S.R.L. (RO); Metrohm Dropsens, S.L. (ES)

Affiliation:

Project website: http://www.nitrisens.ro/

Abstract:

The NITRISENS project aims to develop a method for manufacturing of a portable system for nitrite monitoring in soil based on an innovative electrochemical sensor inserted in a 3D printed soil solution extractor.

Specific objectives of the project are:

- To manufacture of a new cost-effective and robust SPE sensor integrated in a 3Dprinted soil solution extraction system for nitrite determination in soil

- To design and manufacture of an wireless portable detector for nitrite determination in soil using the new nitrite sensors

- To demonstrate the functionality of the nitrite monitoring system for the fast and precise monitoring of nitrite in soil, as well as the soil nitrification process

The integrated platform for on-field measuring of nitrite directly in soil responds to the urgent need of a tool for soil nitrification monitoring and controlling in real-time.

Benefits and market impact: real-time monitoring of soil pollution; reducing of amount of N-fertilizers; potential to introduce on the market of cost effective tools for precision agriculture strategies; widening the range of products of the SMEs involved in project; increasing of the international collaboration in ERA.

Metal-ceramic nanocomposites: next-generation thermal energy storage materials Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2019-1456 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Project partners: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://www.icf.ro/pr_2019/TE166_2020.pdf

Abstract:

Currently, the only “green” technology which can replace polluting coal or gas power plants for continuous energy generation is Concentrated Solar Power. This can be coupled with thermal energy storage, typically using molten salts. However these materials have limited operating temperature range, leading to decreased plant efficiency. The MOST project aims to study innovative metal – porous ceramic composites for high temperature energy storage. The materials will act as shape-stabilized phase-change materials (PCM), using both latent and sensible heat storage. Latent heat storage at elevated temperatures improves the heat to electricity conversion efficiency, yielding lower cost per kWh. This approach is based on a concept demonstrated by the team in 2015, involving the maximization of heat storage agent through nanoconfinement into porous oxide matrices. The projects aims at both fundamental studies of metal/semi-metal nanoconfinement into porous inorganic matrices and applicative research aiming to increase the TRL of these materials to at least 2. A laboratory demonstration of gram-scale synthesis of a nanocomposite PCM with at least 50% wt. metal and shape-stability will be carried out.

The project proposes a multidisciplinary approach and aims to consolidate the research team position as a leader in the field of shape-stabilized phase change materials with high storage potential for elevated temperatures (>200 °C), based on nanoconfinement effects. Furthermore, the project activities are aimed at both applicative and fundamental research, increasing the team international visibility and capacity for further collaborative projects with industry and academia, as well as addressing the important challenge of mitigating anthropogenic carbon emissions associated with energy generation.

Biogenic nano-system for targeted delivery of bioactive ingredients on dysbiosis biofilm involved in gingivitis and periodontitis Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4527 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim.ro/project/bionanogum-en/

Abstract:

BioNanoGum project proposal aims to develop an innovative biogenic nano-system for resolution of dysbiosis oral biofilms and inflammation involved in gingivitis and periodontitis, based on an innovative bacterial nanocellulose - fungal (nano)chitosan stimuli-responsive hydrogel, biogenic selenium nanoparticles (bioSeNPs), and hollow pollen shells filled with biogenic silica nanoparticles (bioSiOxNPs). Gingivitis and periodontitis affect more than 30% of globe population and can lead to teeth loss, but also other complications and severe diseases (Alzheimer, diabetes, autoimmune diseases). SeNPs, silicic acid released from SiOxNPs, and chitosan nano-structures determine (frank) resolution of dysbiosis biofilms and inflammation. However, there are also several drawbacks such as a very narrow physiological window (in the case of Se), or induced inflammation through a MAMPs similar mechanism, mediated by the Toll-like receptors (in the case of SiOxNPs). New formulations are needed in order to reduce risks of negative effects and to optimize the beneficial effects. BioNanoGum will use compounds acting complementary to SeNPs, which will lead to the reduction of Se dose. The pollen shells, obtained by Kombucha fermentation, will be used as encapsulation carriers for SiOxNPs, which allows bearing benefits from the anti-inflammatory, anti-bacterial and wound-healing effects of the silicic acid slowly released from bioSiOxNPs. The biogenic nano-system will deliver different components into a complementary manner and will act both on the resolution of pathogenic biofilms and on that of inflammation. BioNanoGum involves the niche between biotechnology and nanotechnology with health applications. This niche market has a significant growing potential, because it addresses several of the main health problems in the European Union and worldwide, from the beginning of the 21st century : an ageing population, with an increased incidence of non-communicable / chronic disease.

Biotechnological strategies for innovative construction materials incorporating bacterial bioproduct Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-0991 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CEPROCIM S.A. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim.ro/bioconstrmater; https://icechim.ro/bioconstrmater-en

Abstract:

The fabrication of materials from living organisms (bacteria, fungi, etc) could represent a significant domain of biotechnological investigation, with consequence in reducing the negative impact of concrete industry over environment. Microbial induced calcium carbonate precipitation can be incorporate into a technology with beneficial effects on remediation of cement fractures and cracks, improving the durability and reducing the costs with replacement of damaged construction materials.

The project scope is to obtain an innovative bioproduct, used to deliver bacteria to concrete matrix, in order to produce sustainable building materials with enhanced durability.

The degree of project novelty consists in the use of by-products from agro-industry as adjuvants to sustain the bacterial cells survival in mixtures for building materials.

The proposal starts at TRL2, by formulating the technology concept - to obtain an innovative bacterial bioproduct as bacterial cells formulated with agro-industrial by-products, and the application – by incorporating the bacterial bioproduct in mixtures for construction materials in order to improve their durability. The specific objectives envisaged: to optimize the bio precipitation of calcium carbonate at selected strain; to improve the bacterial cells survival in mixtures by adding agro-industrial by-products; to obtain the improvement of construction materials; to test and validate the material improvement on laboratory level, through elaborated technology.

The project is experimentally highly feasible due to the significant biotechnological expertise of the work group of coordinator (INCDCP-ICECHIM), specialized in the obtainment of microbial bioproducts, and partner experience (CEPROCIM SA) to prepare composite materials based on cement and environmentally friendly products from renewable raw materials. From scientific point of view, this approach represents an interdisciplinary connection between biotechnology and engineering.

Advanced material based on push-pull extended π-conjugated azo-chromophores in functional matrices with enhanced NLO properties Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3009 2020 - 2022

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://unibuc.ro/cercetare/promovarea-rezultatelor-cercetarii/proiecte-de-cercetare/proiecte-cu-finantare-nationala/smart-nlo/?lang=en

Abstract:

Scope of the project SMART-NLO is to obtain, optimize and validate the technology of fabrication and the new product based on novel extended azo chromophores in organo-modified silica films, possesing superior NLO properties at TRL4, developed starting from the preliminary results related to other types of chromophores with nonlinear optical (NLO) properties, filmogenic modified silica films and nanocomposite clay-silica materials obtained at TRL2 already achieved by the team’s publications and the existing laboratory techniques. The method of fabrication of novel material consists in encapsulation of the novel chromophores with extended structures in a silica film rational designed to ensure enhanced nonlinear optical properties. Methods of preparation and composition of the silica filmogenic matrix will be adjust to render tunable and efficient advanced materials with suitable arrangement of chromophore molecules and improved stability, for the fabrication of hybrid materials with superior NLO properties. The methods of film formation are chemicals ones, selected to be energy saving and eco-friendly.

New Intelligent Anti-Corrosion Coatings for Active Protection of Metallic Surfaces, Enhanced with Stimuli - Responsive Mesoporous Silica Nanocontainers Loaded with Organic Inhibitors Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2019-2053 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.icechim-pd.ro/en/syst_heter/sisteme_heterogene_corrapel_en.html

Abstract:

The strategic objective of the project respond to the need to accomplish the estimated results of the RESEARCH PROJECTS FOR YOUNG INDEPENDENT TEAMS - PN-III-DCD-RU-TE-2019-2, entitled: „New Intelligent Anti-Corrosion Coatings for Active Protection of Metallic Surfaces, Enhanced with Stimuli - Responsive Mesoporous Silica Nanocontainers Loaded with Organic Inhibitors” are: to develop ability of the young researchers to lead teams and manage research projects and to increase their capacity to implement their own research program. Thus, the proposal aims to create an additional opportunity to strengthen a young research team and an independent research program for it, providing the financial and logistic support necessary for 2 young researchers, 2 postdoc students; 3 PhD students and 1 master’s student to carry out their own research activities and to enable them to achieve international high-level of scientific research. The scientific objective of the project consists in preparation of smart mesoporous silica nanocontainers capable of stimuli-responsive release of the encapsulated corrosion inhibitors (CIs). They will be used as key components for obtaining superhydrophobic silica hybrid coatings with enhanced anticorrosion active protection for metallic surfaces. Optimization of mesoporous silica nanoparticles as pH-triggered opening nanocontainers, Design and preparation of of superhydrophobic film forming silica matrices by a simple sol-gel route in the presence of different nanofillers with oxigen barrier and anticorrosion properties and Optimization of the anticorrosion coatings with integrated nanocontainers will be analyzed in terms of the efficiency of the corrosion resistance of the metal surfaces they cover.

Advanced nanoparticle-based materials with synergistic effect on neuronal oxidative stress and beta-amyloid fibrillation for preventive treatment in Alzheimer's disease Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4657 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.icechim-pd.ro/ro/syst_heter/sisteme_heterogene_nanonerves.html

Abstract:

This project aims to develop and to validate a new product and its technology with application in preventive treatment of Alzheimer's disease. This new product includes bioactive ingredients with effect on neuronal oxidative stress (curcumin) and beta-amyloid fibrillation (Ag and ZnO functionalized nanoparticles), and a nanocarrier (PEG-functionalized silica particles), that can act itself as a beta-amyloid fibrillation inhibitor. The main project novelty is related to: (i) study of the interaction of new formulations based on Ag or ZnO NPs and Curcumin encapsulated in functionalized silica NPs with beta amyloid fibrils and (ii) a sistematic and rational scientific approach to strike a balance between the effect of modifying the kinetics of amyloid beta fibril formation and the prevention of toxic effects (otherwise known) on neurons. Project objectives are: (i) to optimize product components and to improve their compatibility; (ii) to develop demonstration model, through components integration and (iii) to test and to validate the demonstration model, on laboratory conditions. Objectives are related to different TRLs: improved compatibility and optimal composition of new formulations based on Ag or ZnO NPs and Curcumin encapsulated in functionalized silica NPs (1st objective) allow properties analysis and improvement (TRL 3). Components integration (2nd objective) and product testing in laboratory conditions (3rd objective) permit technological development up to TRL 4.

INNOVATIVE 3D PRINTED NANOCOMPOSITE CONSTRUCTIONS OBTAINED FROM MARINE RESOURCES (ALGINATE, SALECAN) AND NATURAL CLAY WITH SPECIFIC APPLICATIONS IN BONE REGENERATION - 3D_ALSAC Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4216 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); GENETIC LAB S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.icechim-pd.ro/en/syst_heter/sisteme_heterogene_3dalsac_en.html

Abstract:

The scope of 3D_ALSAC project is to develop and test demonstrative models for a new product and its associated technology, namely an efficient and improved printing formulation based on an innovative biomaterial, followed by the construction of a multifunctional 3D implant designed for bone tissue regeneration. Based on a solid foundation built from the theoretical and experimental results previously obtained by the partners of the Consortium, thus justifying TRL2, the objective of this project is to target TRL4, where an innovative 3D printed product based on biopolymer-clay nanocomposite will be developed, tested and validated. The concept of the 3D_ALSAC project resonates with the long-term vision of the research teams and especially that of the economic agent, of developing custom extracellular matrices for bone regeneration using the patient's stem cells. Thus, the 3D_ALSAC project opens new possibilities for collaboration with the economic environment in order to implement efficient and cost-effective solutions. The 3D_ALSAC project will lead to the evolution of the fields of materials science and regenerative medicine by repairing parts of the skeleton of the human body using innovative biomaterial based inks and 3D printing techniques and obtaining personalized implants, serving as the basis for new therapies used for bone tissue regeneration. The 3D_ALSAC project will closely monitor the improvement of the Romanian research performance internationally through an intensive and qualitative dissemination plan aimed at publishing at least 4 scientific papers in prestigious and open-access journals, with a cumulative impact factor greater than 15, at least 10 presentations at scientific events, 2 work-shops, 2 patent applications and, in addition, contributions to the development of 2 PhD/master/bachelor theses, according to the intellectual property agreement previously signed between the partners of the Consortium.

Emerging technologies for the industrial capitalization of 2D structures (graphene and nongraphenic) Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0387 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA DIN CRAIOVA (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=49

Abstract:

EMERG2Ind is a complex solution that responds to the needs of Romanian research on one side through a institutional management and development mechanism, but at the same time it is a complex interface tool for the Romanian automotive industry as a development engine and integrator for the horizontal and vertical integration of the Romanian economic resources. International expertise is available in an attempt to develop concrete solutions in the country. Emerging technologies are being developed up to TRL4 and TRL5, through complementary harmonization of three strategic subprojects. The complex project approach is regional and institutional with cumulative indicators that fully meet the requirements and seeks to maximize the use of the funding instrument.

Contingency of CBRN hazards and improvement of national security resources Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0395 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); Ministerul Apararii Nationale prin Centrul de Cercetare Stiintifica pentru Aparare CBRN si Ecologie (RO); Academia Tehnica Militara (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); CENTRUL DE CHIMIE ORGANICA AL ACADEMIEI ROMANE "C.D.NENITESCU" (RO); Centrul de Cercetare Stiintifica pentru Fortele Navale Constanta (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=40&lang=ro si http://icechim-rezultate.ro/proiect.php?id=33&lang=en

Abstract:

SECURE-NET is a Complex Project designed to improve the institutional performance of the Consortium Research Partners (Institutions with Re-launch Capabilities in the Field of National Security). In this respect, the Complex Project proposes five research themes corresponding to the five Component Projects, which aim at: (i) contingency of chemical, biochemical, radiological and nuclear (CBRN) hazards by developing new decontamination products and by developing specific sensors for detecting chemical agents of combat, and (ii) improving national security by developing shock-absorbing composites, solid rocket fuel and multispectral camouflages. This Complex Project brings together institutions with tradition, having either similar specialisation or complementary specialisation, to strengthen scientific and technical competences in the field of National Security and Advanced Materials for military applications. The Project Consortium has a gender-balanced staff and promotes the involvement of a large number of teachers, researchers, doctoral students and post-doctoral students in all activities proposed by the Common Agenda. In addition, the project facilitates the transfer of scientific knowledge between participating institutions as well as the recruitment and training of new staff. The multitude of results generated by the implementation of SECURE-NET express the potential for significant influence upon (i) the scientific community through communication and dissemination of results (as a short- and medium-term impact), and (ii) the public and private environment by promoting new research services and new transferable products / technologies to the external environment of the Consortium, particularly to the national defence industry (as a long-term impact).

Closing the bioeconomy value chains by manufacturing market demanded innovative bioproducts Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0569 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); UNIVERSITATEA "DUNAREA DE JOS" (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); UNIVERSITATEA AUREL VLAICU ARAD (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=51&lang=ro

Abstract:

Agriculture and food industry in Romania generates large amounts of co/by-products, which are not used and turn into wastes, with negative impacts. The approach of the project PRO-SPER is to develop integrated processes, flexible and interconnected, to transform a number of agro-food by-products in bio-products, with market demand. This approach facilitates the achievement of project goals, complex-coordination and linking of the research organizations that are members of the Consortium, INCDCP-ICMPP, UDJ, ICECHIM, INCDSB and UAV, for improving their institutional performance in the field of nano-and bio-technologies of their application into bioeconomy.

The overall objective of the project PRO-SPER is to increase the impact of research and development activities and innovation of the RDI institutions, by developing and harnessing innovative technological solutions for bio-nano-processing of several by-products from the bioeconomy value chains, for recovering and/or formation of value-added components and their use in order to obtain products with high added value.

Expected results through the implementation of the project (21 new jobs, 23 national patent applications and international patent applications 6 EPO/WIPO; 10 technologies/new products resulting from the project, at a level of technological maturity to enable taking over by the operators, 5 services research and technological research services 10 cheques, 10 experiments cheques services

80 internship of young researchers from and within partner institutions, 50 visits for developing new techniques for working jointly in the Consortium, 30 training internships for new employees, 28scientific papers, 1 joint program CDI, in line with the development plan of institutional partners) have a significant impact on the capacity-building of the partners in the Consortium.

Increasing the institutional bioeconomic research capacity for innovative exploitation of local plant resources to obtain horticultural products with high added value Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0332 2018 - 2021

Role in this project:

Coordinating institution: UNIVERSITATEA PITESTI

Project partners: UNIVERSITATEA PITESTI (RO); INSTITUTUL DE CERCETARE-DEZVOLTARE PENTRU POMICULTURA MARACINENI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU BIOTEHNOLOGII IN HORTICULTURA STEFANESTI-ARGES (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); STATIUNEA DE CERCETARE-DEZVOLTARE PENTRU POMICULTURA CONSTANTA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE CRAIOVA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE IN SUDURA SI INCERCARI DE MATERIALE - ISIM TIMISOARA (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.upit.ro/ro/academia-reorganizata/facultatea-de-stiinte-educatie-fizica-si-informatica/departamente-la-nivelul-facultatii-de-stiinte-educatie-fizica-si-informatica/departamentul-stiinte-ale-naturii2/proiect-biohortinov

Abstract:

The complex project Increasing the institutional bioeconomic research capacity for innovative exploitation of local plant resources to obtain horticultural products with high added value comprises the following four projects:

Project 1."Complex electronic system with intelligent algorithms for data processing used for monitoring the developing conditions of water and biocenotic stresses, for warning about their presence and preventing them in horticulture"

Project 2."Multisensory quantification of water and biocenotic stress in horticulture through phytomonitoring and early warning in climate change conditions"

Project 3."Development of plant extracts and innovative phytosynthesized nanostructured mixtures with phytotherapeutical applications aimed at eliminating the biocenotic stress in horticultural crops"

Project 4."Innovative technologies for advanced processing of plant resources from pomiculture and viticulture"

The objectives of the project aim to develop the research capacity of the public organizations involved. Thus, upon the completion of the projects these organizations should meet the following outcome indicators: 1) employing new staff in research positions; 2)training the new and old employees through initial research training courses and specialist courses offered by each of the partners in their own field of competence (using the logistics of the learning resource centers); 3)obtaining new or significantly improved products/technologies/services; 4)structuring the offer for research and technological services and presenting it on the platform www.erris.gov.ro; 5)strengthening the capacity of the partner institutions through recovery strategies such as training programmes (research)/specialization programmes and visits (short-term); 6)offering and performing research services using the available research infrastructure; 7)creating a common programme for the learning resource centers, correlated with the institutional development plan of each partner

Smart materials for medical applications Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0407 2018 - 2021

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); CENTRUL DE CHIMIE ORGANICA AL ACADEMIEI ROMANE "C.D.NENITESCU" (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "GRIGORE T. POPA" DIN IAŞI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://intelmatupb.wixsite.com/intelmat

Abstract:

INTELMAT project represents advanced research in the field of synthesis and application of smart materials for medical engineering in order to solve essential features of some acute/chronic diseases of large occurrence. 5 thematic directions are taking into consideration: 1. Developing of a controlled-release system of complex micro-colloidal architectures based on bacterial cellulose and hydrogels used for management of chronically wounds which aims to overcome the limitations of classical treatments; 2. Developing of new biomaterials specially designed with targeted action for treatment of inflammatory diseases of gastrointestinal segment; 3. Synthesis of new generation of composite membrane materials for artificial kidneys based on biocompatible polymers and derivative graphene; 4. Developing of some auto-assembly 3D platforms with controlled-released drugs based on polymeric nanoparticles and composite nanogels for the therapy of colon-rectal cancer; 5. Developing of innovative technologies for the synthesis of some 1D nano-architectures (nanowires) with controlled morphology, with applications in producing of non-enzimatic electrochemical biosensors.

Energetic efficiency biogas plants improvement by integrated system: biogas-microalgae-biofuels in frame of biorefinery concept (AlgalBiogasConceptEnergy) Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0541 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU INGINERIE ELECTRICA ICPE - CA BUCURESTI (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU CARTOF SI SFECLA DE ZAHAR-BRASOV (RO); UNIVERSITATEA PETROL GAZE PLOIESTI (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-rezultate.ro/proiect.php?id=38&lang=ro; http://www.icechim-rezultate.ro/proiect.php?id=39&lang=en

Abstract:

The complex project propose the development and demonstration of innovative technologies to optimize the biogas plants by integrating the open ponds for microalgae cultivation using the digestate resulted from anaerobic digestion as a culture medium. The integral valorization of microalgae biomass consists in: obtaining of algal extracts (for co-digestion), lipid fraction (for biofuels) and spent biomass (co-digestion substrate); advanced separation and valorization of biogas by carbon dioxide conversion to biomethane; biorefining of the solid digestate and lipid fractions obtained from algal biomass into biochar, fuel components, bitumen fluxes, biohydrogen and liquefiable gaseous fractions. As results of this project will be: a demonstrated technology at TRL 6 level within the biogas-microalge integrated and an experimental stand for the evaluation of biomethane and liquefied gaseous hydrocarbons combustion efficiency and emission control.

Multidisciplinary complex project for the monitoring, conservation, protection and promotion of the Romanian cultural heritage Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0413 2018 - 2021

Role in this project:

Coordinating institution: AGENTIA SPATIALA ROMANA

Project partners: AGENTIA SPATIALA ROMANA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); MUZEUL NATIONAL AL UNIRII ALBA IULIA (RO); MUZEUL CIVILIZATIEI DACICE SI ROMANE (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://ro-cher.rosa.ro

Abstract:

The Cultural Heritage (CH) can represent one of the decisive factors for the standard of living and for the quality of life specific of different communities, can contribute to the prevention of cultural globalization, can support the cultural diversity and can positively influence the economic development. The protection of the CH represents a major concern for decision-makers, local communities and European citizens. At the European Union level, the year 2018 has been declared The European Year of Cultural Heritage. In the same time, Romania faces a very important historical celebration: The Centenary of the Great Union from 1918. The RO-CHER project proposes a multi-disciplinary innovative methodology that integrates high level scientific knowledge for safeguarding the cultural heritage and that targets the development of synergetic scientific activities in the framework of the 4 complementary component projects by: monitoring the CH objectives with the aid of space technologies; development of materials and innovative techniques based on soft nanomaterials for safeguarding the cultural heritage; recommendation of an integrated management system (conservation, restauration, protection) for mobile and immobile CH objectives; promoting CH by using state-of-the-art technologies of digital reconstruction. The specific results indicators, predicted since the pre-implementation phase, are: new jobs in research (7); patent requests (6); results validation and transfer to the economic environment; design and development of the services offer and the research infrastructure; mutual access of partners at equipments and technology; institutional capacity building by internships/training sessions and working visits; joint R&D&I programme, correlated with the development strategy of each partner, all of these leading to the creation of a knowledge cluster, being able to successfully access national and international funding.

Innovative technologies based on polymers for the obtaining of new advanced materials Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0428 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=41&lang=ro

Abstract:

The project is aimed at using the expertise that involved in consortium entities acquired in materials science. The consortium consists of three representative national institutes: INCD for Chemistry and Petrochemistry – ICECHIM Bucharest, INCD for Electrochemistry and Condensed Matter - INCEMC Timisoara and INCD of Chemical Pharmaceutical - ICCF Bucharest, and of two prestigious universities: University POLITEHNICA of Bucharest and the University of Bucharest and a remarkable institute of Romanian Academy: Institute of Macromolecular Chemistry – Petru Poni Iasi. Although having great tradition and noteworthy results, the first five institutions face a series of problems, from the lack of financial funds, equipment and the aging employees for ICCF and partly for INCEMC and ICECHIM, to the lack of highly qualified staff required for recent investments in equipment for all 5 institutions. In this respect, the project attempts relaunching the activity in the first 5 institutions of the consortium, by putting together the existing competencies, so as to develop new technologies in order to obtain new materials with high performance properties. Given that, 3 of the research teams are specialized in polymers (ICECHIM, Petru Poni and UPB) the developed technologies will use the polymers as intermediates or as a component in the finished product. To this end it is envisaged getting the titanium nitride for prosthetic coatings via inorganic-organic polymer nanocomposites, obtaining photocatalytic materials and antibacterial coatings by sol- gel reactions, obtaining of short-life or one-time use biomaterials from aliphatic polyesters and micro or nanocellulose and the development of new polyphase materials with medium or long life, based on biopolymers, through 3D printing. The project intends the full use of A1, A2, B and C checks in order to increase the institutional performance of partners.

Production of ferulic acid, 2,3 Butanediole and microbial plant biostimulants from lignocellulosic biomass by a two-step cascading process Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-FACCE-SURPLUS-DEBUT 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); ENPRO SOCTECH COM SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=46&lang=ro

Abstract:

The DEBUT project aims to develop a small biorefinery process, with two steps: 1) biomass pre-treatment with natural deep eutectic solvents (NaDES); and 2) one pot production of a versatile chemical, 2,3 butanediol (2,3-BD), from NaDES pre-treated lignocellulose biomass, by simultaneous saccarification and fermentation (SSF), performed by a plant biostimulant microbial consortia. The main biochemicals resulting from the biorefinery process are phenolic acids, specially ferulic acid, and 2,3-BD. Phenolic acids address mainly health and wellness-related industries, whereas 2,3-BD is a versatile chemical, with a fast-growing market. The proposed biorefinery process produces also agricultural inputs such as lignin, minerals and microbial plant biostimulants. A first project novelty is related to the use of a plant biostimulant microbial consortium for simultaneous saccarification and fermentation of lignocellulose. According to our knowledge such approach has not been done yet. On such process there are no by-products – recalcitrant lignocellulose, not converted to 2-3 BD, together with embedded microbial biostimulants biomass, is a useful agricultural input - a microbial plant biostimulant. Process up-scale to TRL5 is done also in an innovative manner, through adaptation of the already known equipment to newly developed technology. For NaDES extraction we propose to use the continuous operated reconfigurable columns systems, applied for decades for various types of extraction (e.g. for extraction of soluble from coffee). For SSF with microbial plant biostimulant consortium we propose the use of vacuum operated ploughshare mixer. This approach will ensure not only a better recovery of volatile 2,3 BD, but also a higher specificity of the fermentation medium, due to micro-aerobic conditions. The DEBUT project proposes a new approach of small scale biorefinery, compatible with a farm facility, which valorises agricultural side streams, with recovery of minerals and lignin (main precursor of soil organic matter) for agricultural use, and production of an innovative agricultural input, a microbial plant biostimulant. The project proposes a biotechnological two step cascading process, which converts excess lignocellulosic biomass into biochemicals (phenolic acids, 2,3 B-D), with added-value and fast-growing market. The main innovative solutions, NaDES and microbial plant biostimulant, are investigated for their potential adverse effects by a battery of state-of-the art techniques, in an trans-national partnership, to ensure that they do not affect natural ecosystem productivity.

Biocompatible multilayer polymer membranes with tuned mechanical and antiadherent properties Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2016-2164 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim-rezultate.ro/proiect.php?id=35&lang=en

Abstract:

Post oncologic intervention prosthetic materials are made from synthetic polymers which induce significant clinical complications such as fistula formation, erosion of adjacent organs, intra-abdominal adhesions, infections and inflammation besides pain. Thus, designing novel biomaterials able to overcome these disadvantages have become an important goal for the scientific community. The proposed project aims to develop new biocomposite systems with tailored antiadherent and antibacterial functions in the form of a membrane with multilayer structure (BIOMULTIPOL), intended for pelvic prosthetic meshes. The objectives of this project will be achieved through the use of polymers with improved biocompatibility: nanocellulose (NC), poly-L-lactic acid (PLLA) and poly(3-hydroxybutyrate) (PHB), these materials exhibiting an increased resistance to bacterial infection compared to non-biodegradable synthetic materials. The project approach is new and is based on the association of different biocomposite layers, each having a well defined function, thus mimicking the natural structures. Another innovative aspect is related to the multiple role of NC, which enhances the mechanical properties and improves the biocompatibility of the BIOMULTIPOL membrane, eliminating the mesh-related complications. The proposed BIOMULTIPOL membrane will assure the needed mechanical support (Lm layer), antiadherent (La layer) and antibacterial (Lb layer) properties. Various highly hydrophobic compounds and different antibacterial agents will be screened for achieving the desired antiadherent and antibacterial properties.

The assessment of the BIOMULTIPOL membrane model for biomedical applications will be performed based on the analysis of physico-chemical and mechanical properties and on the complex biological evaluation (biocompatibility, antibacterial and biodegradability tests).

Advanced hybrid surfaces for biosensing Bacteria Endotoxins Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2016-1006 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=34&lang=en

Abstract:

One of the current global issues refers to drinking water or food quality and medical hazards from the exposure to pathogenic bacteria. Despite the gross investment on research to reduce the incidence of infections in humans, the simplest and most successful strategies in preventing bacteria spreading have proven to be the best hygiene practices. Hence, bacterial contamination can be prevented if properly detected. In this respect, biosensors can be applied to a large variety of samples including body fluids, food samples, cell cultures to analyze environmental samples. As a result, the project BACTERIOSENS proposes the preparation of advanced hybrid surfaces (namely molecularly imprinted polymer nanofilms, MIP NFs) able to sense lipopolysaccharides (LPS)-the endotoxin membrane of Gram negative bacteria (GNB). This is a multidisciplinary project resulting in innovative synthesis technologies for LPS-MIP NF and LPS biosensors. The specific output of the project will lead to various outcomes during project implementation (mid-term scenario: at least 3 ISI publications and 3 communications, 1 national patent claim and website of project) and also after project end (long-term scenario: new research themes, research and development roadmaps, performance data, transferable knowledge to lead-users). The scientific outcomes are expected to have several impacts with potential benefits within scientific, economic and social areas at the national level (during project implementation) and at the international level (when the innovative technologies for the preparation of LPS biosensors are transferred to potential beneficiaries). The work plan and methodologies are straightforward and the resources (meaning the infrastructure: laboratories and instruments; and the highly qualified Project leader and the young team members: 3 Postdocs, 2 PhD fellows, and other 5 young specialists) are well-balanced according to the activities employed for the project successful implementation.

Innovative green technologies for valorisation of lignocellulose Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2016-2518 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=29&lang=en

Abstract:

The scientific scope of the INTELIGRENCE project is to develop an innovative green technology, based on natural deep eutectic solvents (NADESs) and enzymatic processes, for multi-stage cascading use and valorisation of lignocellulosic biomass. The following interrelated specific objectives will be addressed: (1) to elaborate NADESs with high feruloyl esterase (FAE) compatibility and ability to extract ferulic acid (FA) from biomass; (2) to develop NADESs for cellulose valorisation into nanocelullose and the subsequent saccharification of the polysaccharides; (3) to investigate and optimize the use of selected NADESs in a multi-stage cascading processing of a lignocellulosic substrate. The project brings several innovative elements: the first time use of a high-throughput experimentation (HTE) approach for characterization and optimization of NADESs-based formulations for lignocellulose processing; in-situ lipophilisation of FA and generation of secondary (hydrophobic) NADESs from FA; the use of NADESs in association with enzymatic cocktails incorporating the recently discovered lytic polysaccharide monooxygenases (LPMOs) during the second step of the multi-stage cascading approach. The applied direction is related to the high added value of the main products (ferulic acid and nano-cellulose) intended to be obtained from lignocellulose by the proposed cascading NADES-enzymes treatment approach. Ferulic acid is an ideal precursor for the production of bio-vanillin and it exhibits a wide variety of biological activities, having a market which will exceed $100 million (US), mainly due to the increased demand for anti-aging serum based on ferulic acid. Nanocellulose market will exceed $250 million (US) in 2023, due to applications related to composites, packaging, coatings, biomedicine and automotive. The new scientific data will be relevant also for the biological significance of NADESs that are formed from components which are normally present in biological systems.

Bactericidal hybrid surfaces against Gram-negative and Gram-positive pathogenic bacteria: Smart Tools for Wastewater Purification Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-M-ERA.NET II-TANDEM 2017 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); EDAS-EXIM SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=25&lang=en

Abstract:

After major efforts for hygienize the wastewaters, the presence of pathogenic bacteria is still detected in the water, soils and even crops, causing public and environmental hazards. This issue is of high concern as most pathogens responsible for waterborne diseases originate from faecal or food waste contamination caused by insufficient- or not treated wastewater. As a result, TANDEM project focuses on developing innovative and efficient bactericidal hybrid surfaces for Gram-negative and Gram-positive bacteria that can be transposed into special building blocks (i.e. smart tools) for creating more efficient bio-tanks and sustainable wastewater purification technologies with regard to pathogenic bacteria removal. The project consortium is well-balanced having aside two renowned RT&D entities from Romania and Norway that will guaranty the successful implementation of the project. In addition, one medium enterprise from Romania is entrusted with prototyping/testing the tandem bio-tank.

Ligand-free targeted delivery nanogels for phospholipase A2 retention Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2016-1876 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim-rezultate.ro/proiect.php?id=32&lang=en

Abstract:

It is well known that the venom from the Hymenoptera insect class (bees, wasps, ants) are potent neurotoxic due to secreted phospholipase A2 enzyme (PLA2). For instance, bee venom PLA2 enzyme acts synergistically with the polyvalent cations (toxins) in the venom creating an increased haemolytic effect and a quick access of toxins into the blood flow, targeting important organs like the brain, kidney and liver. In spite of recent technological developments, effective and safe therapies are currently not available for treating the victims of mass insect attacks. Yet, thanks to advances in the fields of Nanotechnology, removing of PLA2 enzyme from sting zone, can be accomplished by targeted delivery systems called ligand-free nanogels. The proposed concept for preparing ligand-free nanogels is original and uses bifunctional macromonomers, small molecule cross-linkers and PLA2 template molecules to create antibody-like recognition sites for PLA2 subsequent retention. Hence, PLANano holds significant influence upon the scientific community by new concepts and methodologies for free-ligand nanogel targeted delivery systems (short-term impact: 3 ISI papers, minimum 3 communications, 1 national patent claim, web site of project) and by opening new research directions associated with the side-impacts of the research (like new imuno-therapies) as long term impact. Implementation of this project will also bring specific scientific, economic and social benefits at the national level and at the international level. The greatest impact is given by the health value, if taken in consideration the advantages of the innovative ligan-free nanogels over conventional antivenom production. Plus, the existing infrastructure of the Host Institution is appropriate to sustain the proposed tasks for PLANano successful implementation. But most importantly, the young research team composed of young specialist, post-docs and PhD fellows is highly qualified in this direction.

Development of a demonstrator to produce next generation plant biostimulants based on root exudates Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-MANUNET III-DEMETRE 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CHEMI CERAMIC F SRL (RO); RODAX IMPEX S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=47&lang=ro

Abstract:

Plant biostimulants are a new class of agricultural inputs, which increase nutrient uptake and nutrient use efficiency, improve plant tolerance to abiotic stress and enhance crop quality. The DEMETRE project aims to develop and to validate devices, tooling and equipment needed to (bio)manufacture a new product, from the (emerging) next generation of plant biostimulants. The proposed new plant biostimulants product is based on concentrated bioactive compounds from root exudates. The main innovation overcurrent state-of-the art is related to the new, flexible (bio)manufacturing method, which join two known products in a two-in-one synergic product. During its use, the proposed two-in-one product will fulfill two functions: as soil conditioner and as reservoir for the slow release of the selected bioactive compound(s). The needs addressed by the project DEMETRE are related to: (i) agricultural market requirements for new inputs, reducing the consumption and the environmental impact of agrochemicals while maintaining / increasing profitability; and (ii) societal requirements for a circular (bio)economy, wherein the loop is closed due to the valorization of agroindustrial byproducts. In the last years the interest of the economic agents and researchers for the development of new, more active plant biostimulants have been growing. Such active ingredients were proposed to be searched among exosignals, which regulate the plant – beneficial microbes interactions. Root exudates are a source of chemical signals shaping rhizosphere interactions, thus are a logical target to produce next generation plant biostimulant.

Nanocellulose 3-D structures for regenerative medicine Call name: P 4 - Proiecte de Cercetare Exploratorie
PN-III-P4-ID-PCE-2016-0431 2017 - 2019

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=35

Abstract:

Regenerative medicine and tissue engineering may offer new hope of life in case of loss or malfunction of a tissue or organs. One of the key elements in tissue engineering is the three-dimensional (3D) scaffold which provides structural support for cell attachment, proliferation and differentiation. Polymer scaffolds are preferred in tissue engineering to avoid problems related to donor immune rejection and pathogen transfer. Cellulose, the most abundant natural polymer on earth, is an almost inexhaustible source of valuable materials and has gained high interest in the form of nanocellulose (NC). NC stands out for its high crystallinity and mechanical strength, good biocompatibility, high water-holding capacity and large surface area and it has been intensively studied for medical applications because it does not cause toxic or allergic side effects in contact with living tissue. 3D scaffolds should possess a network of interconnected pores to permit cell migration, diffusion of nutrients and clearance of wastes, they must be able to support cell adhesion and promote cell growth and they must have balanced stiffness-toughness properties to support and transfer loads. To meet all these requirements in porous 3D scaffolding, CELL-3D has as main objective to design new nanocellulose 3D structures that can be applied in tissue engineering by: a). synthesis and characterization of nanocellulose 3D structures using surface functionalization and crosslinking; b). synthesis and characterization of 3D structures from nanocellulose - biopolymer composites; c). designing new processing techniques for 3D nanocellulose structures. Biopolymers such as polyhydroxyalkanoates and other aliphatic polyesters with good elongation and flexibility will be used to obtain highly porous 3D composite structures.

New functionalized medical devices for surgical interventions in the pelvic cavity Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-MANUNET III-MedIn-1 2018 - 2019

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=37&lang=en

Abstract:

The incidence of cancer of all kinds is growing all over the world, and thereby the number of surgical

interventions in the field of oncological surgery records a continuous growth year after year. In some cases, the complete resection of one or more organic structures (rectum, uterus, ovaries, and bladder) from the pelvis is required. These surgical interventions, called pelvic exenteration or evisceration, are associated with a high postoperative morbidity and mortality. One of the complications is related to occlusions and fistulas, when the intestinal loops adhere to the perineal plain. The pelvic prosthesis developed in MedIn project will be designed to fill the empty excavation, support the intestinal loops and prevent any inflammatory phenomena caused by the adherence of perineal tissue. Other complications which may occur after pelvic exenterations refer to overall infectious, hemorrhagic complications, surgical infections. In general, wound infection associated with

pelvic exenterations is reported to be as high as 40%. This remained and unmet need will be covered through the innovative oxygenated wound dressing that will be developed within the scope of this project.

Manufacturing of new analytical systems for toxin hazard assessment in diary industry Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-MANUNET II -TOX-HAZ-ASSESS 2017 - 2019

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); EPI-SISTEM S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://tox-haz-assess.ro/

Abstract:

Project aims to develop a new manufacturing method for an analytical system, based on an innovative combined surface-plasmon resonance - electrochemical platform integrated into an on-line flow analysis configuration. The project is co-ordinated by ICECHIM, the biggest R&D institute in chemistry field from Romania. Partners are DropSens, a very successful SME from Asturias, Spain and Epi Sistem, an ambitious SME from Romania. Partners’ expertise, capabilities and market share complete each other in a synergic way, due to the research subject complexity and interdisciplinarity: from immunoassay concept to flow immunoanalyzer design and optimisation; from manufacturing of devices to final integration of the analytical system for toxin hazard assessment in dairy industry.

A next generation plant biostimulants product Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0253 2017 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CHEMI CERAMIC F SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=33

Abstract:

This project aims to develop and to validate a new product, from the (emerging) next generation of plant biostimulants. This new product includes concentrated active ingredients, from a new bio-resource, and a carrier, acting itself as a plant biostimulants. Plant biostimulants assure sustainable intensification of agricultural production, in face of major challenges. The main project novelty is related to: (i) the active ingredient concentration process, from a new bio-resource, assisted by a new electrochemical technique, for peroxynitrite determination and (ii) the formulation process, wherein a carrier with biostimulants characteristics is used. The existing category of non-microbial plant biostimulants are extracts of organic fertilizers / organic amendments, traditionally used in agriculture. Organic non-microbial plant biostimulants shall contain “carbon of solely animal or plant origin” (COM (2016) 157), thus the next generation of more active and more efficient plant biostimulants will be concentrated bioactives from the present / existing extracts. Project NEXUS objectives are: (i) to optimize product components and to improve compatibility; (ii) to develop demonstration model, through components integration and (iii) to test and to validate demonstration model, on laboratory conditions. Objectives are related to different TRL. Improved compatibility and optimal composition of microalgae extract (1st objective) allow critical function and/or characteristic analysis and improvement (TRL 3). Components integration (2nd objective) and product testing in laboratory conditions (3rd objective) permit technological development till TRL 4. The project work plan is divided into 6 activities (Work Packages): WP1 Humic acids loaded macroporous ceramics; WP2 Optimized microalgae concentrated extract; WP3 Concentrated bioactives inclusion into humic acids – porous ceramic; WP4 Bioassay of biostimulant activities; WP5 Dissemination and exploitation; WP6 Management.

Conversion of phytogenic silica reach food industry by-products into value-added products Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERA IB2 ERANET-ERA-IB-15-129-Convert-Si 2016 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); LABORATOARELE MEDICA S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=48&lang=ro

Abstract:

Convert-Si project aims to develop optimized processes for a total conversion of industrial plants by-products into value-added products. Main innovative contribution is related to the introduction of a (pre)treatment step based on new microbial products: non-catalytic small proteins from cerato-platanin family (CP), which weaken (ligno)cellulose structure, metabolites from silicon solubilizing microorganisms (SiM) and super-active ligno-cellulolytic enzymes Convert-all project integrated approach is intended to close a biomimetic industrial symbiosis. The by-products of one conversion process represent raw material for other conversion steps. Convert-Si proposed cascade process is applied to two value-added chains: cereal husks and/or bran, fruit/grape pomace. From these the following ingredients are recovered: anti-oxidant polyphenols and/or feruloylated oligosaccharides, useful for new cosmetics and dietary supplement products; essential oil terpenes and (brassino)steroids, trapped and/or bounded by/to lignocellulose network, with plant growth stimulating and/or insects repellent activities; biosilica (BSi); fermentable carbohydrates, recalcitrant lignin. BSi, fermentable carbohydrates and recalcitrant lignin are converted into mesoporous silica nanoparticles, value added fermented food / feed (probiotics) supplements and, respectively, substrate for plant biostimulants formulation. Mesoporous silica nanoparticles are used for the “ smart”, controlled released formulation of the recovered polyphenols, essential oils, and (brassino)steroids. Recalcitrant lignin, together with the biomass of CP producing microorganisms and, respectively, SiM will be used for the production of a complex plant biostimulant. Safety and efficacy of biosilica nano-particles and “smart” formulated phytoextracts will be tested by state of the art high through-output cell assay.

Removal of hardly biodegradable organic compounds (Endocrine Disruptors) from water by using Advanced Oxidation Processes based on new innovative catalysts Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2016-0063 2016 - 2018

Role in this project:

Coordinating institution: I.C.P.E. BISTRITA S.A.

Project partners: I.C.P.E. BISTRITA S.A. (RO); UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icpe-bn.ro/pagini/60-oxydep.html

Abstract:

Hardly biodegradable organic compounds, in particular endocrine disruptors, is an important component of pollution of the aquatic environment and water resources with a major impact on ecosystems and human health, which can not be addressed by conventional remediation technologies. These pollutants originate from chemical synthesis compounds resulting from the the various branches of the economy. An important source of these compounds consists of pharmaceutical, personal care products and pesticides. A laboratory validated technology for remediation of water containing hardly biodegradable organic compounds will be transferred to industrial partner, and as a result of the project, this technology will be validated in industrial environment. Also the functionality and the efficiency of this technology will be proved. The core of this technology is based on Advanced Oxidation Processes (AOP- in particular catalytic ozonation) using of innovative new catalysts previously developed by research organizations partners. The industrial research activities will result in the catalysts activity optimization and also in the development of a new advanced oxidation reactor. Based of this technology, a prototype of an new water remediation module will be developed with the industrial partner contribution. As a result of solid experience in the field of water treatment systems and production of specific equipment of the industrial partner, the prototype will be a fully automated operational one. The new developed technology, targeted to all organic pollutants, will be an environmentally friendly one and will display a high efficiency, a low energy consumption, with low operational costs. This technology is both addressed to wastewater treatment plants and to drinking water treatment plants.

Contributions to enhancing the Sanimed SRL’s competitiveness by the knowledge assimilation and potential production implementation of some 3D collagen-polymer hybrid matrices intended to tissue repair Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0397 2016 - 2018

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.unibuc.ro/prof/micut_m/

Abstract:

The project proposal mainly aims at knowledge transfer to economic operator regarding the obtaining and development of 3D collagen-polymer hybrid biomaterials intended to biomedical applications. The practical implementation of the proposal should lead to enhancing competitiveness of private economic entity in order to develop itself in the near and middle-term future. In line with economic partner, the public entities University of Bucharest and ICECHIM (project partners) have identified aspects of scientific and technological existing at private partner, the weaknesses and strengths of these aspects, as a useful basis for designing new collagen-based hybrid biomaterials. In addition, the purpose that such kind of biomaterials be used in the process of tissue repair requires accounting a number of key characteristics against which it is possible to design, realize and develop this kind of hybrid collagen-polymer system: biocompatibility, bioresorbability, mechanical properties, internal and external morphology and manufacturing technology.

Increasing performance/competitiveness by improving the technology of smart products fabrication with superior biocompatibility and antibacterial properties for cosmeto-medical applications Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0142 2016 - 2018

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); SONNENKREUZ SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.unibuc.ro/n/cercetare/94BG-2016.php

Abstract:

The purpose of this project is to increase the performance and the competitiveness of SC Sonnenkreuz SRL by using the expertise existing in the research organizations, University of Bucharest and INCDCP-ICECHIM, for developing and optimizing the modern technology for producing silver colloid dispersions, in order to obtain a product with higher biocompatibility and antimicrobial properties. To accomplish the purpose of the project, a full compliance between the requirements and the problems identified by the economic agent and the project objectives was followed. Two directions for innovating the final product and the manufacturing processes will be pursued: (i) obtaining of various colloid silver dispersions stabilized with polymers having intrinsic antibacterial activity, to achieve a synergistic effect and (ii) optimizing the production technology by electrochemical method by ensuring the control of nanoparticles growth. The knowledge transfer will include also the collaboration with the economic agent in order to identify the possibility of a subsequent development of other cosmeto-medical products based on the dispersions of silver nanoparticles with improved properties. For developing the quality assurance system at the economic agent, the collaboration between the partners UB and INCDCP-ICECHIM with SC Sonnenkreuz SRL will be intensified in order to accomplish the analyzes required for the characterization of the final products and to monitor the manufacturing process. Cooperation with the economic partner will be fulfilled by the activities of entrepreneurship knowledge transfer towards the researchers/PhD students/Master students involved in the project. Development of the new product and improvement of the technology will provide opportunities for practical training for master students, with a complex topic. The publishable scientific results will be widely disseminated in communications and articles in specialized journals.

Nanocellulose based biocomposites with integrated antibacterial activity by submerged liquid plasma Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0287 2017 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=26&lang=en

Abstract:

Biocomposites from polyhydroxyalkanoates (PHAs) and nanocellulose (NC) are cutting edge materials for in vivo biomedical application as scaffolds or implants. Poly(3-hydroxybutyrate) (PHB), the most studied of the PHAs is available as industrial grade and it is considered as viable alternative of petroleum-based materials. However, PHB and cellulose themselves have no antibacterial activity to prevent bacterial infections associated with medical devices that constitute the most important cause of hospital death which could be prevented. The scope of this project is to obtain PHB/NC biocomposites with antibacterial activity using eco-friendly submerged liquid plasma (SLP) and nanotechnology. The research topic of plasma submerged or in contact with liquids is new but very important for the functionalization of nanomaterials or synthesis of unconventional polymers with valuable properties for biomedical applications. In the frame of CELLAB-SLP, the biomaterial and eco-friendly technology will constitute the experimental model that will be developed and tested at lab-scale. The new biomaterial will be validated in a third-party laboratory from the point of view of bactericidal effect and biocompatibility. The new biocomposite will show (i) good processability by compression, extrusion or injection molding in films, plates, tubes or rods as models for biomedical devices; (ii) good mechanical properties and thermal stability; (iii) strong and persistent antibacterial activity beside biocompatibility. The balanced profile of the staff involved in the project (36% senior researchers, 32% postdoctoral researchers, 1 PhD student and 13% technicians), the good expertise of the two teams and the necessary infrastructure will ensure the implementation of the project.

Novel anti-corrosion and anti-icing ZnO nanostructured materials obtained by ecofriendly methods – NOCORIC Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-1332 2017 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-pd.ro/ro/syst_heter/sisteme_heterogene_nocoric.html

Abstract:

NOCORIC project consists in designing of new nanostructured organic-inorganic hybrid materials for coating of metallic surfaces (e.g. zinc, aluminium, copper). Techniques used in this project for the synthesis of coatings for metallic substrates, are the sol-gel process and the ecofriendly synthesis - supercritical fluids. These technologies will not affect the quality of the environment, thus are included in the category “ecological and high tech”. The project aims to identify the success factors and the difficulties in obtaining of coatings on metals with protection against corrosion and anti-icing, and their influence on economic activities. The approach is original, combining the production of coatings from zinc oxide type materials and organic-inorganic hybrids with physical properties of surfaces. Depending on the stability of the dispersions obtained from the sol-gel process, silica precursors with various functionalities will be used. Both the Coordinator (ICECHIM) and Partner 1 (UB) have experience and results in synthesis of zinc oxide nanoparticles through sol-gel process and characterization of nanoparticles morphology. Another novelty is corroboration of sol-gel synthesis (easy composition control, film homogeneity, low cost, facile fabrication) with supercritical fluid method, which tends to be closer with “green chemistry”. Currently, this „eco-friendly” method is not investigated enough for zinc oxide materials and organic-inorganic hybrids. Partner 1(UB) has experience in synthesis of zinc oxide nanoparticles through ecofriendly supercritical fluids synthesis. Nanostructured materials characterization will be realized to assess the hydrophobic and morphological characteristics: dynamic light scattering, environmental scanning and transmission electron microscopy, FT-IR spectroscopy, contact angle measurements etc. The corrosion resistance of obtained hybrid films deposited onto metal substrates will be studied by a third partner.

Optimization and validation of an advanced material and technology default based on biopolymer-modified clay as carriers for controlled release of doxorubicin in gastrointestinal tract Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-1896 2017 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL DE BIOCHIMIE (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-pd.ro/ro/syst_heter/sisteme_heterogene_doxsaclay.html

Abstract:

The goal of the project DoxSaClay is to obtain, optimize and validate a new product and the associated technology reffering to the advanced material “biopolymer IPN hydrogel networks-modified clay-bioactive agent”. Preliminary results related to polymer-advanced modified clay nanocomposite materials are already demonstrated by the team’s publications. The consortium offers a high level of competencies in biomaterials domain, the Project Coordinating team having a great expertise in the synthesis of advanced materials while the competencies of Partner being related with in vitro testing on cell lines. The method will connect Salecan biopolymer with pH responsive (co)polymers to design new semi-interpenetrated networks (SIPN) with encapsulated amphiphilic nanoclays by free cross-linking radical co(polymerization) to render tunable and efficient advanced materials with enhanced mechanical strength, improved stability and adjustable responsive properties, for the controlled release of anti-cancer drug-doxorubicin in gastrointestinal tract. New delivery methods, particular delivery of doxorubicin, could make a dramatic impact to the medical community who administers the cancer treatment and the patient who endure the effects of the cancer treatment. The local, oral delivery of anti-cancer drugs to the colon maybe made possible by using designed technology, own modified clays and biopolymer semi-interpenetrated networks, by assembling them into novel structures and architectures that can exhibit properties appropriate for the application at hand. Validation of the results will be achieved by ISI publications in prestigious peer-reviewed scientific journals, conferences with international visibility and at least one patent request. Another priority of the present project is to increase the international visibility and competitiveness of Romanian research for successful integration in European Projects (Horizon 2020).

Innovative ferrite/beta-cyclodextrin core-shell nanocomposites for removal of inorganic and organic pollutants from aqueous effluents Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0251 2017 - 2018

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.unibuc.ro/prof/avramescu_s_m/NanoFerDeX.php

Abstract:

Adsorption process is effective in removing certain organics but a large part of inorganic and organic pollutants cannot be removed using existing adsorbents Nanotechnology is an enabling technology that can help address key needs relating to energy, environment, health and agriculture all over the world.

This project proposes a new and innovative class of nanoadsorbents with core–shell morphology. These nanoadsorbents will be made from ferrite particles (core) and cyclodextrin moieties (shell) in order to benefit from outstanding properties of both materials: magnetic properties of ferrites nanoparticles and high adsorption capacity of cyclodextrin molecules. These nanoadsorbents will be used in treatment of wastewaters containing organic and inorganic pollutants. After thorough assessment of operational parameters at laboratory scale the prepared core-shell adsorbents will be tested at pilot scale in order to confirm, through their physical-structural and chemical properties the utility of these materials in water treatment processes.

“New drug delivery systems based on micro/nanogel composites containing natural bioactive substances” Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-0953 2015 - 2017

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-rezultate.ro/proiect.php?id=22

Abstract:

The overall objective of the project consists of obtaining micro/nanoparticles of covalently crosslinked hydrogels based on polyethylene glycol and aliphatic polyamines (injectable micro/nanogels) having embedded both natural nanozeolites but also of natural bioactive substances in their polymer structure, with potential pharmaceutical applications. These new micro/nanogel composite structures are of great interest as they are aimed at being used as devices for subcutaneous or intravenous injection, ensuring the release of bioactive substances in hard-to-reach areas (by macroscopic hydrogels). The role of natural nanozeolites incorporation is to allow for a much slower and controlled release of the embedded active substances and to improve the viscoelastic features of hydrogels. Nowadays bioactive substances play an important role in the development of controlled release systems in medicinal chemistry for the production of new drugs with fewer side effects. The use of phytoextracts as bioactive substances is a big challenge of the project proposal. These new micro/nanodevices with controlled release will have significant influence, both nationally and internationally on the scientific, social and economic field. The results will be disseminated as follows: three articles published in ISI journals; three scientific communications at international conferences, and patenting of any original aspect.

New nanosized cellulose fillers for fully biodegradable packaging solutions Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-1139 2015 - 2017

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-rezultate.ro/proiect.php?id=23

Abstract:

The importance of the project goal arises from the rapid increase of packaging consumption and resulting waste, most of them being from synthetic polymers which are not biodegradable for hundreds of years. This project aims to replace the petrochemical based packaging materials with polymers derived from renewable biomass feedstock thus reducing the environmental pollution and providing simplified end-of-life disposal. This goal will be achieved through the use of biodegradable polyesters (polylactic acid (PLA), polyhydroxyalkanoates (PHAs)) and nanosized cellulose fillers (CN) isolated from a cheap source, namely fruit seed shell waste. Exploiting such inexpensive sources like crop waste for CN isolation and high value added products will contribute to solve the emergent problem of increased biomass and will reduce the cost of the new designed polymer nanocomposites. The new concept of “zero-waste” will be also demonstrated in this project. Innovative technological routes will be applied for the design of new advanced and fully renewable CN/biopolymers for packaging industry. Specific melt processing tests will be performed for developing high quality extrusion films and injected parts designated for niche packaging application, for example childcare products.

MULTIFUNCTIONAL AND INNOVATIVE PRODUCTS FOR SAFE AND BIOENHANCED FUNCTIONAL FOOD FROM NEWLY CULTIVATED PLANTS IN ROMANIA Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0995 2014 - 2017

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); HOFIGAL EXPORT IMPORT SA (RO); CHEMI CERAMIC F SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://produse.multifunctionale.icechim.ro

Abstract:

Thematic area of the project proposal is in the field of functional foods destinated to maintain human health in concordance with research theme 5.1.6. Functional foods to maintain human health and prevent diseases, Domain 5. Agriculture, food safety and security.

The general project objective is to develop multifunctional and innovative products for protection of nutraceutical plants newly introduced in Romania (Momordica charantia and Passiflora incarnata) and to stimulate concomitantly formation of biologically-active compounds in these plants, at stable levels and with reproducible biological effects. The specific innovative project objectives are: 1. development of multifunctional for treatments of soil and in vegetation, based on: (a) consortia of Trichoderma strains; (b) porous ceramics with high bioavailability of silica; (c) essential oils included in mesoporous silica; 2. Testing products, developing methods of application and integrating them with the sustainable cultural technology of nutraceutical plants; 3. characterization of functional foods through in vitro alternative tests on human cell cultures and highlighting the biological role of silica forms accumulated in treated plants in animal cells; 4. results exploitation by protection of intellectual innovative solutions after techno-economical analysis and opportunities of results exploitation.

Products based on consortia of Trichoderma strains and essential oils have multiple actions as: plant protection agents towards biotic stresses (phytopathogens, pests), elicitors of plant defence response, limiting agents for the negative effects of ethylene on roots and growth promotor of plant nutrition, mainly with nitrogen.

Porous ceramics containing silicaxerogel, applied as soil treatment, work as a matrix for controlled release of nutrients with high bioavailability and have role to compensate losses of plant metabolic energy due to the synthesis of secondary metabolites and to supply orthosilicates with high bioavailability.

Silicon with high bioavailability supplies also mesoporous silica as a carrying for controlled release of essential oils. The silicon’s role as an important element for plants is to activate and balance - concomitantly and non-antagonistically – the different ways of plant defence system and of stress hormones biosynthesis (salicylic acid, jasmonic acid and ethylene/abscisic acid) in plant pathosystems.

This project proposes for the first time to study interaction of silicon, Trichoderma and essential oils treatments, protection agents with multiple roles, which activates simultaneously plant defence response. It is the first proposal aiming the development of some products with applicability directly into practice, in which silicon is controlled released from supports, having concomitantly the functional role as a matrix, from which nutrients and volatile oils are smart-delivered, in this why pointing out the possibility of practical use of silicon in order to balance the main signalling pathways in plant defence response, integrated with elicitors for obtaining high productions with raised phytonutrients level.

The highlight of silicon’s role in animal and plant organisms (having into account the unity in diversity of the life world), the (meso)porous silica forms as a support for controlled release of some active ingredients and of bioavailable silicon, compatibility of the Trichoderma consortia with the other products for the directed activation of plant resistance, will be the coagulation axis of this trans-disciplinary approach, revealing - also - the existence of synergies between partners in the frame of MAIA Project.

Thermosensitive energy saving systems with tailored solar reflecting/absorbing properties for construction structures Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-1391 2012 - 2016

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); CHIMCOLOR S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.thermosolar.roit.ro

Abstract:

In principle thermochromic and thermotropic systems can function as energy saving systems. For high temperatures, during summertime thermochromic coatings have the ability to reflect solar energy, reducing the surface’s temperature; while in wintertime absorb solar energy, increasing the surface’s temperature as reversible color change takes place. Applied thus on external building surfaces, they have the potential for the reduction of heating and cooling loads, contributing to the reduction of urban temperatures, fight heat island and reduce air pollution.

Color-changing compounds have become increasingly important in recent years in the study and the production of thermochromic coatings that is coatings which respond thermally to their environment, changing reversibly their color from darker to lighter tones as temperature rises. The novelty comes from the use concomitant of thermotropic hydrogels which respond thermally by changing transparency from total transparent to translucent. Combining these features of termotropic hydrogels and thermochromic dyes we can obtain complex thermosensitive systems that respond to an increase in temperature by switching the color hypsochromically while accompanied by a change in transparency of the hydrogels.

During the project we intend to develop thermosensitive energy saving coatings that action on the entire Vis-NIR range and are most typically applied to roofs but additionally can also be applied to exterior and interior walls in much the same way. Thermosensitive coatings that will aim to obtain change reflectivity and color as a function of temperature, present enhanced weathering and durability and may be in any suitable formulation for application on roofs or walls such as water-based, oil-based, epoxy-based or acrylic-based formulations.

On the advanced processing of marine algae from Romanian Black Sea edge Call name: P 3 - SP 3.1 - Proiecte de mobilități, România-Franța (bilaterale)
PN-III-P3-3.1-PM-RO-FR-2016-0031 2016 -

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); SIGMA Clermont (FR)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website:

Abstract:

In toata lumea algele si-au gasit multe aplicatii datorita continutului lor bogat in glucide, lipide si proteine. Cele mai faimoase alge din Romania sunt cele marine care vara invadeaza litoralul. Pe plajele din Romania se intalnesc alge verzi (51%), alge rosii (35%), alge galbene (10) si alge albastre (5%), ce ofera pe zi de vara posibilitati de colectare de peste 2000 t/zi. Din punct de vedere tehnologic acestea pot fi tratate ca materiale vegetale, putand fi procesate in scopul separarii din acestea a componentilor proteici, lipidici si carbohidratici care au utilizari de alimente respectiv de materii prime pentru fermentatii orientate producerii de biocombustibili. Propunerea de fata urmareste: i) determinarea compozitiei colectei de alge specifica litoralui romanesc; ii) determinarea cerintelor si solutiilor de procesare locala a colectei de alge, inclusiv prin macinarea umeda si tratarea enzimatica a pulpei; iii) utilizarea ultrafiltarii ca solutie de separare din hidrolizatul enzimatic a unor concentrate specifice; iv) determinarea compozitiei concentratelor de ultrafiltrare si a comportarii toxice a acestora; v) testarea de solutii tehnologice de valorificare a concentratelor extrase inclusiv ca publere cu folosinta de supliment alimentar. Propunerea are elemente puternice de originalitate intre care se mentioneaza cele referitoare la incercarile de tratare enzimatica a pulpei de alge si a utilizarii ultrafiltrarii ca solutie de separare a procesatului enzimatic

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects