BrainMap

Mrs. Cornelia Alina Marinescu

Researcher

Researcher - INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Researcher | Scientific reviewer

Expertise & keywords

Research of the bone substitution with biocomposite materials processed by powder metallurgy specific techniques Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-2094 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA DIN CRAIOVA

Project partners: UNIVERSITATEA DIN CRAIOVA (RO); TEHNOMED IMPEX CO S.A. (RO); SPITALUL CLINIC DE URGENTA " BAGDASAR-ARSENI " (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://mecanica.ucv.ro/Cercetare/BONY/index.html

Abstract:

The research proposal is entitled “Research of the bone substitution with biocomposite materials processed by powder metallurgy specific techniques”, acronym BONY. Its general objective is to obtain advanced biocomposite materials, based on hydroxyapatite (HAP) matrix reinforced by Ti-based powder particles. The osseointegration process is accelerated by the natural organic esters of Bor, as a component of the biocomposite powders mixture. The applications aim the bone substitution by small-sized reconstructions for skull and vertebrae body.

BONY project matches the priority domain 7 (Materials, innovative processes and products), research area 7.1 (Advanced materials), research topic 7.1.6 (Advanced materials and biomaterials for life quality improvement (health, sport, education etc.)).

The project relevancy is underlined by the necessity to elaborate bone implants for skull and vertebrae by advanced biocomposites, with improved osseointegration capacity to the adjacent native bone tissue. Also, the technical and economical savings are important as far as the processing technologies concern.

The BONY project results are:

1. the innovative biocomposite material as bulk product for vertebral implant processed by micro-injection moulding technique;

2. the innovative biocomposite material as coating for skull implant processed by MAPLE technique on Titanium substrate;

3. the innovative material and method to accelerate the osseointegration process of the bone implants.

The innovative/original aspects of the BONY project are represented by:

- the innovative combination of metallic and ceramic powders, micrometric and nanometric sized. The advanced sintering techniques as well as the coating ones provide hybrid structured biocomposites that assure improved physical, mechanical, technological and biochemical properties relative to the native bone.

- using, for the first time, of the micro-injection moulding technique, to process complex shaped and small sized bone implants;

- the original an innovative application of MAPLE coating technique to process hybrid biocomposite coatings on Ti substratewith similar properties to the bulk biocomposites type.

- the original method to accelerate the osseointegration process by using special additives, Bor natural organic esters, in special technological procedures.

The BONY implant biocomposites provide the following advantages as follow: resorbability, geometrical stability, improved lifetime, micro-machinability for final geometrical adjustments, able to be processed as complex shapes and small dimensions, improved osseointegration.

The impact of the project results may be evaluated from the following points of view: scientifical (innovative biocomposite materials), technological (suitable processing technologies to the implants shape and size), research human resources training (young Ph.D. students or graduated, members of consortium), economical and social (improving the patient’s life quality).

The quality, expertise and research, innovative and entrepreneur skills of the BONY partners assure the successful fulfilment of the project objectives. The BONY consortium is represented by: CO – University of Craiova (UCV); P1 - S. C. Tehnomed Impex Co S.A., Bucuresti (IMM); P2 – The Emergency Clinic Hospital „Bagdasar-Arseni”, Bucharest; P3 – The National Institute for Laser, Plasma & Radiation Physics (INFLPR), Bucharest ; P4 – « Ilie Murgulescu » Institute of Physical Chemistry of the Romanian Academy (IPC), Bucharest ; P5 – Politehnica University of Bucharest (UPB).

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List of research grants as project coordinator
List of research grants as partner team leader
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects