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Romania
Citizenship:
Romania
Ph.D. degree award:
2011
Cosmin-Mihai
Cotrut
Dr.eng.
Associate Professor
-
UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI
Other affiliations
Visiting Professor
-
Tomsk Polytechnic University
(
Russian Federation
)
Researcher | Teaching staff | Scientific reviewer
15
years
Web of Science ResearcherID:
G-4505-2011
Personal public profile link.
Curriculum Vitae (02/10/2019)
Expertise & keywords
Corrosion science
Electrochemistry
Biomaterials
Surface engineering
Coatings
Electrochemistry and Corrosion
Surface coatings
Surface treatment
Projects
Publications & Patents
Entrepreneurship
Reviewer section
Biodegradable Implants from Magnesium Alloys used in Foot and Ankle Surgery
Call name:
Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-2267
2014
-
2017
Role in this project:
Key expert
Coordinating institution:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI
Project partners:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); INSTITUTUL DE BIOLOGIE SI PATOLOGIE CELULARA ,,NICOLAE SIMIONESCU'' (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO); MEDICAL ORTOVIT S.R.L. (RO)
Affiliation:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)
Project website:
http://www.biomagia.eu
Abstract:
The field of medical materials is very important into the general frame of materials science. The advanced technologies from engineering and medicine developed in the last years, associated with the society demand related to the better daily life conditions and returning to work after some trauma followed by the bone fracture make this field to be a dynamic one. As a consequence, many new materials and implantable medical devices were developed recently and the tendency is to continue those efforts using an interdisciplinary approach based on the knowledge and skill from different field like materials science, physics, biology and medicine.
Also, there is a need in healthcare for cost-efficient treatments, including those for implantable devices for orthopaedic surgery. Foot & ankle surgery is an emerging direction of the orthopaedic surgery and the number of patients who need this kind of surgical intervention is higher. At this moment, is clearly an intensive trend in orthopaedic surgery to use the bioresorbable implants for trauma surgery, but for the foot & ankle surgery the resorbable trauma implants made by polymeric (PLLA) or composite materials (PLLA reinforced with TCP or Hap) didn’t show the clinical advantage because the implants didn’t have a necessary mechanical properties and their degradation rate is much faster than the healing of bone fracture. Magnesium alloys are strong candidates for obtaining biodegradable implants who require better mechanical properties, biocompatibility and slow degradation rates. The consortium that made the BIOMAGIA project proposal is interdisciplinary and comprises a university, two research institutes and two companies. The partners are one of the best research groups in their field (UPB-materials science/biomaterials; INOE200-physics/coatings; IBPC-biology/biocompatibility testing; R&D-materials industry/casting, processing metallic materials; MOV-medical devices industry/medicine, instruments and implants for orthopaedic surgery), with strong skills, capacities, and who were involved in many national and international projects. BIOMAGIA will contribute to the major demand for intelligent biomaterials and smart implants in orthopaedic surgery which are resorbed by the body upon remodelling the bone tissue by the development of new aluminium free magnesium implant materials with tailored properties specific for a biodegradable implant used in foot and ankle surgery. To reach this goal, carefully selected materials and processing routes will be combined with a comprehensive research to elucidate the correlation between magnesium alloys chemical composition, microstructural aspects and processing techniques, surface modifications, related to the corrosion processes in vitro and in vivo who modulate the degradation rate, hydrogen release, and implant resorbtion. The project members are confident that based on their skills and previous results will be able to pass the current barriers like the absence of specific commercial magnesium alloys tailored for orthopaedics applications, the manufacturing technology and the lacking scientific knowledge about the degradation rate based on the corrosion mechanism, hydrogen release and toxicity. The ultimate goal of the project will be a prototype implant for foot & ankle surgery with a new design based on the achievements in this consortium, which brings together leading scientists from various research fields: material scientists and mechanical engineers, physician and experts in surface engineering, biologist and medical scientists. BIOMAGIA collectively covers basically all aspects, the instrumental techniques and approaches necessary to tackle successfully the challenge to understand, and ultimately control, interactions at the material-bone interface. The full achievements of this research are gained because we cover the full value chain from fundamental engineering research towards hospitals and in vivo studies and implant production.
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Multifunctional coatings for load bearing implants made of a novel titanium-based alloy
Call name:
Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1958
2014
-
2017
Role in this project:
Partner team leader
Coordinating institution:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD
Project partners:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL DE BIOLOGIE SI PATOLOGIE CELULARA ,,NICOLAE SIMIONESCU'' (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO); TEHNOMED IMPEX CO S.A. (RO)
Affiliation:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)
Project website:
http://www.osseopromote.inoe.ro./
Abstract:
The actual challenge in the orthopaedic surgery is to obtain orthopaedic implants with good mechanical, physical, chemical and surface compatibility with the bone. But the difficulties are remarkable, because these characteristics fail in time and, in general, it is difficult for a single material to have all the required properties.
The main goal of the present project is to give innovative solutions to increase the service life of load bearing implants by:
- Preparation in a levitation melting furnace of a novel type of alloy consisting of only biocompatible elements (Ti, Zr, Nb), in order to replace Ti6Al4V, the most popular alloy in the present, but which consists of elements (Al, V) causing cytotoxic and allergic reactions. The novel alloy is I nsystem Ti-Zr-Nb. It is expected that an optimum Nb content in the alloy composition will be found, for achieving a Young’s modulus close to that of the bone, which was an important target for the researchers in the last two decades.
- Preparation of novel types of osteoconductive coatings, by magnetron sputtering method, as follows:
• osteoconductive coatings in mono (type 1) and bilayer (type 2) structures, in order to enhance the osteoconductive capability of the TiZr30Nbx alloy:
˗ type 1: MeC+IA (Me-metal, C-carbon, IA-inorganic additive), by addition in the MeC film composition (Me = Ti, Zr, Nb) of small amounts of various IA (Ca3(PO4)2, TiSi);
˗ type 2: MeC/(IA + TiO2), where IA is Ca3(PO4)2 and MeC is the bottom layer and (IA+TiO2) is the top layer. It is expected that such structures will reveal an optimum combination of the coating microhardness, adhesion, residual stress, toughness, friction, corrosion-wear resistance, osteoconduction and biocompatibility. The MeC films are produced to enhance the adhesion of the osteoconductive coatings to metallic substrates, because the films consist of elements which are found in the bioalloy composition.
• use of a complex magnetron set-up, containing a high vacuum system and equipped with 5 different cathodes made of pure metallic or alloyed targets, able to work simultaneously or alternatively.
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Biocompatible coatings for enhanced bond strength of ceramic to metal in dental restorations
Call name:
Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-1240
2012
-
2016
Role in this project:
Project coordinator
Coordinating institution:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI
Project partners:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "GR. TH. POPA" (RO); DIPADENT GROUP SRL (RO)
Affiliation:
UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)
Project website:
http://www.coat4dent.eu
Abstract:
The main scientific objective of this project is to obtain a new variety of high bond nanostructured coatings, based on nc-MeN/a-Si3N4 and nc-MeON/a-Si3N4 nanocomposites (nc-nanocrystalline, a-amorphous, Me – metal (Ti, Zr, Cr or Al), N – nitrogen, O - oxygen), in mono, multilayered and graded structures, with good hardness, high adhesion to metallic and ceramic substrates, low internal stress, high resistance against wear, corrosion and oxidation, high fracture toughness, good biocompatibility to tooth and to oral environment.
In the present project we propose to enhance bond strength of ceramic to metal in dental restorations by inserting novel biocompatible nanocomposite coatings between the metal and ceramics, by means of the cathodic arc technique:
- nanocomposite single layer coatings (nc – MeSiN or nc – MeSiON), where Me is Ti, Zr, Cr or Al,
- nanocomposite mutilayer coatings (nc – MeSiN/MeN and nc – MeSiON /MeN),
- nanocomposite graded MeN/MeSiN/MeSiON coatings.
The scientific expectation is that such coatings enhance the adhesion of ceramic to metallic substrates (NiCr or CoCr alloys), leading to longer service life of the dental restoration. Also, the proposed coatings would effectively prevent the adverse oxidation of NiCr and CoCr alloys and would ensure good biocompatibility in oral environment, having colours close to natural teeth. The great challenges of the project are to obtain a high bond of ceramic to metal and dental restorations with color closed to natural teeth.
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FILE DESCRIPTION
DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects
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