BrainMap

Mr. Cristian Pirvu

PhD

Professor - UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Researcher | Teaching staff | Scientific reviewer

Publons/ResearcherID: V-4619-2018

Expertise & keywords

New nanostructured multifunctional coatings for orthopaedic implants Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0473 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO); TEHNOMED IMPEX CO S.A. (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: http://www.unibuc.ro/n/cercetare/proiecte/PCCA_2532014.php

Abstract:

The materials used for internal fracture fixations and joint replacements are all currently made of metals. However, metallic implants suffer from two shortcomings, one being the poor interfacial bonding between the metallic surface and surrounding bone, and the other the higher rigidity of metallic implants than that of natural bone. Additionally, complications associated with implants due to bacterial-induced infections arise frequently. The implant anti-bacterial function set additional challenges for implant development besides the requirements for osteoblast fixation, mechanical, and biomechanical constraints, consequently in many cases almost incompatible demands have to be met. For osseointegration it is important to promote osteoblast fixation and to avoid bacterial adhesion at the same time. But, cells and bacteria respond differently to implant surface parameters and this gives an opportunity to look for an optimal solution. The present life expectancy of metallic implants is estimated at 10-15 years. Taking into account the ageing of the population, a second implantation becomes more and more often necessary. Surgical revision, however, can be twice as expensive as the primary operation and may lead to significant complications, including infection, deformity, pain, and loss of mobility. This research project is proposed to adress these issues.
A new metallic material (low elastic modulus titanium alloy) with two types of nanostructured coatings, titanium oxide nanotubes and carbon nanowalls, respectively, will be designed, developed and investigated for optimal implant fixation through innovative integration of material science, physics, chemistry and life science. Cerium oxide nanoparticles will be immobilized by electrodeposition to provide the coatings with antibacterial properties. This new beta-titanium alloy along with the new coatings will impart to orthopedic implants the excellent corrosion resistance, adequate strength, enhanced mechanical compatibility, and good bioactivity for promoting bone tissue regeneration and fixation of implants, and to prevent bacterial infections, offering an innovative solution to all of the issues faced by the present metallic implants.
Functionalized surfaces will be fully characterized for physical properties, chemical composition and biological activity. In vitro biological studies will include adhesion, proliferation and differentiation of osteoblasts, assessment of inflammatory cytokines, nitric oxide release and foreign body giant cell formation in macrophage cultures. In parallel Staphylococcus aureus and Escherichia coli adhesion and biofilm formation on experimental titanium surfaces will be analysed. Collation of all the data will be performed to select from the alternatives the optimal coating. As proof of concept, the fabrication of orthopaedic implant demonstrator is envisaged.
To achieve the research goals, nine work packages have been established, and a research team with all of the requisite expertise has been formed. We firmly believe that the synergism of this research team will allow us to successfully conduct this multidisciplinary project and push the frontier of the field of orthopedic biomaterials.
The results of this project will have favorable social and economic impacts on society because the quality of patient life using the new implants could be improved greatly. Moreover, a reduction in the need for revision surgery could translate into reduced health care costs. The broad impacts of this program will also be evident in our strong commitment to human resource development.

Improving oral and systemic health using dental works from modified alloys Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0869 2014 - 2017

Role in this project:

Coordinating institution: UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA

Project partners: UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); UNIVERSITATEA BUCURESTI (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO); DENTAL ART GROUP SRL (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: http://cercetare-umf.ro/proiecte_parteneriate

Abstract:

The project proposal entitled “Improving oral and systemic health using dental restorations from modified alloys” is addressed to the priority field 4 Health and has as goal the improvement of oral and systemic health of the population through implementing new methods of prevention and intervention at national level having capacity of international expansion. Having the central objective the improvement of the health level mainly through the offer of medical services of prevention, the project will contribute to the reduction of costs in the field of health. The offer is elaborated under the competent and representative direction of the University of Medicine and Pharmacy “Carol Davila”, the Faculty of Dental Medicine, another 2 Universities, 1 Institute of research of the Romanian Academy and 2 co-financing SMEs. This consortium is by definition inter- and pluri-disciplinary and exhibits synergy and complementarity due to the contribution of Medicine, Chemistry and Biology to the achievement of the central objective and it shall benefit of the un-financed support of an European partner (Universita’ del Piemonte Orientale “Amedeo Avogadro”) well known in the field of oral pathology, partner which shall participate to the activity of research and dissemination of results. This partner with experience and tradition will enhance the chances of the project both at level of the choice of the best methods of prevention and intervention in oral health and also at the level growing the visibility of the research. As derived objectives to achieve the central goal, the project takes into consideration the formation of target groups of patients according to the following criteria of selection: the detection of lichenoid reactions, of a metallic pigmentary lesions; the existence of dental alloys (CoCr, CoCrMo, etc. used at mass level) which favoured the release of ions and the absorption due to materials imperfections. The project will also form proof-lots including in the study a high number of patients comprising also patients who did not use dental alloys, fact which will allow the set out of the cause of the diseases and of the most appropriate treatments for all the studied cases. Both the scientific background and the expertise of the 6 partners as well as the richness of human and material resources represent a warranty that it is possible to overlap the knowledge about the creation of an improved alloy (CoCrZr or Nb) capable to reduce the potential for serious diseases such as Lichen Planus. The project analyses the sick tissue and the amount of ions released chemically and biologically and to compare the behaviour of the existing materials with that of our new alloy. The improvement of the dental alloy will aim at both the composition as well as the surface state at micro- and nano- level. The trial of these materials will be performed in simulating conditions respecting the corresponding regulations form the European space of operation including the norms of bio-ethics and bio-security and the informed agreement of the patient. The results of the project will be disseminated and exploited both at level of health services as well as at level of co-financing partners who will develop technology and innovating dental works from improved alloys at reduced costs, fact that emphasizes the co-relation between the thematic of the project and the strategy of development of the SMEs partners. Obtaining a patent and publishing 5 research works in international publications of high impact is a prognosis of result indicators that complete the process indicators. The benefits of implementing the project and its exploitation after ending will grow the quality of life through precocious detection of diseases and their treatment and also through the proposal of a new less dangerous and less toxic alloy. The co-financing SMEs will develop as well the commercialisation capacity subsequent to the production of materials with high market potential.

SENSORS FOR METALS BASED ON AZULENES MODIFIED ELECTRODES FOR WATER QUALITY MONITORING Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-2151 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); CENTRUL DE CHIMIE ORGANICA AL ACADEMIEI ROMANE "C.D.NENITESCU" (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU ECOLOGIE INDUSTRIALA - ECOIND (RO); ANALIST SERVICE SRL (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: http://SEMEMA.inoe.ro

Abstract:

Electroanalytical chemistry can play a very important role in the protection of our environment. In particular, electrochemical sensors and detectors are very attractive for on-site monitoring of priority pollutants, as well as for addressing other environmental needs. Such devices satisfy many of the requirements for on-site environmental analysis. They are inherently sensitive and selective towards electroactive species, fast and accurate, compact, portable and inexpensive. Such capabilities have already made a significant impact on decentralized clinical analysis. Yet, despite their great potential for environmental monitoring, broad applications of electrochemical sensors for pollution control are still in their infancy.
The proposed research project entitled SENSORS FOR METALS BASED ON AZULENES MODIFIED ELECTRODES FOR WATER QUALITY MONITORING, acronyme SEMEMA can have a notable significance to the development of the knowledge in this area. Its theme regards the development domain of some electrochemical sensors based on modified electrodes with polyazulene complexing films, being a domain of major interested in the international research. The propose research regards the way to obtain some amperometric sensors sensitive to pollutants as the heavy metals, especially mercury, copper, lead and cadmium, but not limited to these species.
The project fits the global research in macrocyclic and macropolicyclic host systems, like crown eters and cryptands. From relevant molecules in supermolecular chemistry, capable to selectively link organic or inorganic species, either charged or not, there are some that can be considered elementary. They feature recognition properties on which, after functionalization, a thin layer of sensor can be obtained through electropolymerization. Typically, the transposition of properties from homogenous to a heterogeneous system has the following advantages: usage of a significantly smaller amount of ligand as compared with the same system in a homogenous state, the possibility of automating the analysis method in a technological flow (on-line system), miniaturization of the detection system.
This project fits the domain of materials, processes and innovative products (7), Technologies and high precision mechanical products and mechatronic systems (7.3), Equipment and high precision devices for testing and controlling the environmental parameters and primary food quality (7.3.10) and proposes research in obtaining new electrochemical sensors for metals in water. The project is based on research synergy of partners with multidisciplinary talents from two universities University Politehnica of Bucharest - coordinator CO, Ovidius University of Constanta – partner P2, three research and development institutes - the C.D. Nenitescu Centre for Organic Chemistry of the Romanian Academy – partner P1, the National R&D Institute for Optoelectronics – INOE 2000– partner P3, and Romanian National Research and Development Institute ECOIND– partner P4, as well as an economical agent interested in research in physical and chemical sciences SC ANALIST SERVICE SRL – partner P5.
The coordinator and its partners have a material infrastructure well suited for completing the project objectives and the necessary human resources (43 persons involved, out of which 30% are young). The described activities are matched with the human and material resources of partners, specifically: synthesis and characterization of organic compounds (P1), determination of electrochemical properties and film formation expertise (CO, P1), recognition properties in homogeneous phase (P2), experience in manufacturing and testing prototypes and patenting (P3), experience in testing and validation of new methods (P4), practical/current experience in testing water content using classical and advanced analytical methods (P5).

Novel battery based on ionic liquids and nanostructured anode Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1561 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); UNIVERSITATEA PITESTI (RO); GLOBAL RESEARCH S.R.L. (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: https://cssnt-upb.ro/pro/batiolnan/

Abstract:

Our project refers to the design and elaboration of a new type of high energy density electrochemical battery. This subject is strongly related to the research theme 2.1.4. “Promoting clean energy technologies, environmental protection measures and reduction of greenhouse gas” of the thematic area “Energy”. This relationship comes from several directions: electric cars, replacing those propelled by combustion engines, energy storage (coming mainly from non-constant “green” sources), increased efficiency of the batteries used as energy supplies of electronic instruments.
We propose a novel design of an innovative battery including new nanostructured anode materials, a new electrolyte, based on ionic liquids and new ions to replace Li, e.g., Al and Mg in the new substrate for anode.
An essential part of the challenge of the above battery is designing new nano-textured materials used in the negative electrodes of batteries. We shall try two types of new nanostructured anode materials: one based on titanium dioxide (TiO2 nanotubes and nanopowders) and intermetallic compound nanostructures like NiSn, CoSn and CoSb, in order to increase the specific area of the electrode and to improve the battery performance by a facile ion insertion. Using titanium dioxide (TiO2) as host anode material can be profitable because the cost of titanium oxide is low, the methods of obtaining controlled structures are well known and handy, and its structure is a welcoming host for cations. Intermetallic compounds, especially those of tin are very promising anode materials for Li batteries, and it seems that such structures are essential in the case of Mg.
The electrolyte proposed to be studied and used in this project is an ionic liquid synthesized by the combination of imidazolium based cation and TFSI anion, mixed with pyrrolidine (PY)-based ILs. In this way essential requirements for the electrolyte such as high conductivity, low viscosity, a well stable electrochemical window, and negative enough reductive potential value will be fulfilled.
New metals will be investigated to replace Li in our battery, because lithium is difficult to handle in normal conditions, relatively expensive and exhibits not high enough performance required by nowadays technologies. Magnesium and aluminum ions can be an alternative because of their higher valence which provides a distinct advantage in their capacity for energy density over the existing lithium-ion battery (1000 and 1060 Wh/kg respectively vs. 406 Wh/kg).
Several novelties are associated with the present project proposal: (i) the structure of materials intended to be produced using electrochemical processes such as TiO2 nanotubes and nanostructured intermetallic compounds for anodes; (ii) the insertion of magnesium and aluminum ions into the above mentioned anode materials; (iii) the use of more environmentally friendly ionic liquids as electrolytes in batteries; (iv) the design and implementation of a battery prototype. Additional novel aspects of this research will arise during the development of the experiments, such as the impact of metal impurities, the dendrite formation (mechanism, methods to inhibit their growth, influence on the charge/discharge cycles).
This application has a strong inter-, multi-, and trans- disciplinary character because it involves competence from many fields: electrochemistry regarded from both sides – chemistry and physics (electricity), mechanical and thermal investigations, etc.

Technologies and smart products for prevention and treatment of mastitis in productive ruminants, based on green chemistry of the composites for veterinary public health (GREENVET) Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0415 2014 - 2017

Role in this project: Project coordinator

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE-I.N.C.D.T.P. BUCURESTI SUCURSALA BUCURESTI INSTITUTUL DE CERCETARE PIELARIE - INCALTAMINTE I.C.P.I. (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); ROMVAC COMPANY S.A. (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: http://www.icechim.ro/polimeri/proiecte/greenvet/

Abstract:

GREENVET project is a multidisciplinary answer for mastitis treatment in productive ruminants by integrating scientific research from outside discipline, inside the veterinary public health. The solution consists in innovative composites using green chemistry, supramolecular structures and intelligent materials using natural sources for one of the most expensive and health risky disease in livestock production. A final treatment will be developed as product, for internal market but with high export potential. The product consists in an integrated complex system with natural bioactive components (essential oils) as cure for sustaining or alternative to classical antibiotics, anti-inflammatories and cicatrizants with high impact on quality of life: problems of food supplies and quality, health and sustainable resources. GREENVET assumes a consortium (2 unique and large national research institutes, the largest technical university from Romania and the largest producer in Romania for veterinary products) with both experienced and young researchers. The management consist in the classical: planning, organizing and controlling in order to attain a minimum risk for project implementation (specific risk in multidisciplinary research), but is based on latest trend in the field -less graphs and more people- concept, by motivational approach and a proven background history of the collaboration between partners. GREENVET consortium experience in biomedical solutions is focused on the project working plan and provides outputs in terms of experimental models, prototype set, innovative technology, patent claim, dissemination in ISI journals and scientific events, documentation for product registration/or product notification. The budget breakdown and plan is well balanced to the resources to be committed in work complexity and less in time length of the task for people with different skills in multidisciplinary research.

Improvement of biomedical implant properties by surface nano-architecturing and antibacterial protection Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0855 2014 - 2017

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Project partners: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE CANTACUZINO (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO); TEHNOMED IMPEX CO S.A. (RO)

Affiliation: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Project website: http://www.icf.ro/pr_2014/PN-II-PT-PCCA-2013-4-0855/SursaDeFinantare.html

Abstract:

This project proposes the obtaining of a novel, advanced, biocompatible Ti-Ta-Ag bioalloy for orthopaedic and maxillofacial implants with complete innovative composition and properties. Two Research Institutes, one University and two SMEs will resolve in synergetic, multi and inter-disciplinary way the following main scientific objectives: a) elaboration of a novel, original ternary Ti-Ta-Ag bioalloy that contains only non-toxic and non-allergenic elements (Ti and Ta) and an antibacterial element (Ag), assuring increased corrosion resistance, very low ion release, high bioactivity and bacteriostatic activity to avoid adverse reactions in the human body; b) the functionalisation of the alloy surface by introduction of antibacterial nano-particles to increase the antibacterial properties; c) nano-architecturing of the alloy surface with nano /-tubes, /-channels, /-fibres which will stimulate the implant direct attachment and rapid bone healing; d) assessment of the alloy chemical composition and structural characteristics by high level techniques; e) determination of the alloy mechanical properties by static and dynamic tests; f) alloy long-term electrochemical behaviour and corrosion resistance in artificial human biofluids simulating the severe functional conditions of an implant, using modern electrochemical methods; g) monitoring of the quantity of ions (specially Ag+ ions) released into biofluids by high level techniques to know the release rate of Ag+ ions from the bulk alloy; h) establishment of the nano-architecture with the most optimal properties of the stability, roughness, porosity by world level techniques; i) determination of the bacteriostatic capacity of the new alloy before and after its surface functionalisation and nano-architecturing; j) evaluation of the alloy biocompatibility in as-cast, functionalised and nano-architectured state by in vitro and in vivo studies. The project technological objectives are: a) laboratory technology of the alloy synthesis by the modern melting method in vacuum levitation furnace with cold crucible; b) laboratory technology for the surface functionalisation with antibacterial nano-particles having suitable properties of the stability and antibacterial ability; c) laboratory technology for the surface nano-architecturing by the application of nano /-tubes, /-channels, /-fibres; e) two technologies for the orthopaedic and maxillofacial implants obtaining; d) fabrication of the orthopaedic and maxillofacial implants – demonstrator products. The original and innovative contributions of the project are: a) novel, biocompatible ternary Ti-Ta-Ag alloy; b) a new, complex functionalisation and nano-architecturing of the alloy surface; c) elaboration of the original mechanisms of electrochemical behaviour for the as-cast, functionalised and nano-architectured alloy in simulated physiological solutions; d) scientific novelties concerning the modelling of the physical processes at the interface between new bioalloy and simulated biofluids; e) monitoring of the bacteriostatic activity by the modern techniques; f) prime novelty determination of the bare and structured alloy biocompatibility by in vitro and in vivo tests; g) original data bank regarding physico-mechanical, electrochemical, anticorrosive, surface, biocompatible, antibacterial characteristics of the novel bioalloy. The obtained orthopaedic and maxillofacial implants will fulfill the multiple, complete functions and properties of a good implant, actually non-existing on market.

NEW CONCEPTS AND STRATEGIES FOR THE DEVELOPMENT OF KNOWLEDGE OF NEW BIOCOMPATIBLE STRUCTURES IN BIOENGINEERING Call name: Complex Exploratory Research Projects - PCCE-2008 call
PN-II-ID-PCCE-2008-0248 2010 - 2013

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA DIN BUCURESTI-DEPARTAMENTUL DE BIOCHMIE SI BIOLOGIE MOLECULARA

Project partners: UNIVERSITATEA DIN BUCURESTI-DEPARTAMENTUL DE BIOCHMIE SI BIOLOGIE MOLECULARA (RO); INSTITUTUL DE BIOLOGIE SI PATOLOGIE CELULARA NICOLAE SIMIONESCU-LABORATORUL DE CELULE STEM SI TERAPIE CELULARA (RO); UNIVERSITATEA POLITEHNICA BUCURESTI-FACULTATEA DE CHIMIE APLICATA SI STIINTA MATERIALELOR (RO); UNIVERSITATEA POLITEHNICA BUCURESTI-CENTRUL NATIONAL DE CONSULTANTA PENTRU PROTECTIA MEDIULUI (RO); INSTITUTUL DE CHIMIE FIZICA ILIE MURGULESCU (RO); UNIVERSITATEA BABES-BOLYAI CLUJ-NAPOCA, CENTRUL DE BIOMATERIALE, INSTITUTUL DE CERCETARI EXPERIMENTALE SI INTERDISCIPLINARE (RO); INSTITUTUL DE CERCETARE-DEZVOLTARE PENTRU CHIMIE SI PETROCHIMIE BUCURESTI (RO)

Affiliation: UNIVERSITATEA POLITEHNICA BUCURESTI-CENTRUL NATIONAL DE CONSULTANTA PENTRU PROTECTIA MEDIULUI (RO)

Project website: http://www.pcce248.weebly.com

Abstract:

IN TISSUE ENGINEERING (TE) THE COMBINED KNOWLEDGE FROM BIOLOGY AND ENGINEERING
IS DIRECTED TOWARDS THE POSSIBILITY TO RESTORE LOST OR DAMAGED TISSUE. THE
GENERAL AIM OF THIS PROJECT IS TO CONSOLIDATE A CROSS-DISCIPLINARY TEAM OF
COLLABORATING INVESTIGATORS TO CARRY OUT SOME CELL-SUPPORT CONSTRUCTS (CSC)
WITH POSSIBLE APPLICATIONS IN REGENERATION/REPAIR OF SOFT AND HARD TISSUES AND IT
DOES NOT ASSUME PRE-CLINICAL AND CLINICAL TRIALS. THIS APPLICATION CONTAINS THREE
SPECIFIC OBJECTIVES: 1- OBTAINMENT OF NEW SUPPORT 3-D STRUCTURES DESIGNED TO
CULTIVATE OSTEOBLASTS AND HUMAN MESENCHYMAL STEM CELLS (HMSC) TO OBTAIN CSCS
WITH CHARACTERIZED ARCHITECTURE AND MECHANICAL PROPERTIES, USEFUL IN BONE TISSUE
ENGINEERING; 2 - DEVELOPMENT OF REGENERATION STRATEGIES OF ADIPOSE TISSUE BY
IMPLANTATION OF PREADIPOCYTES IN 3-D HYDROGEL SCAFFOLDS, THAT MIMIC
EXTRACELLULAR MATRIX, DESTINED TO THE RECONSTRUCTION OF SOFT TISSUE DEFECTS
(SEVERE TRAUMAS, DEEP BURNS OR TUMOR RESECTIONS) AND 3 - STUDY OF THE EFFECTS OF 3-
D CULTURE AND GROWTH FACTORS ON THE CHONDROGENIC DIFFERENTIATION OF HMSC CELLS
TO OBTAIN SOME INVESTIGATION MODELS OF THEIR POTENTIAL IN CARTILAGE TISSUE
REGENERATION. THE PROJECT PRESENTS VIABILITY, INNOVATION, COMPLEXITY AND
INTERDISCIPLINARY EXCHANGE BECAUSE: 1 - IT IS A CONSORTIUM WHICH CONSISTS FROM
PARTNERS WITH COMPLEMENTALLY COMPETENCES WHO ENGAGE TO ACT AS A UNITY IN THE
FOLLOWING FIELDS: CELLULAR AND MOLECULAR BIOLOGY, CHEMISTRY AND PHYSICS OF
MATERIALS, ENGINEERING SCIENCES – IN ORDER TO GET ALL OBJECTIVES; 2 - THE PARTNERS
ARE STAFFS WITH A GOOD, STRONG REPUTATION ON THEIR FIELD, AND THEY HAVE THE
NECESSARY MANAGERIAL EXPERIENCE AS WELL AS THE HUMAN RESOURCES AND PERFORMING
EQUIPMENTS AND 3 - THE PARTNERSHIP WAS PARTIALLY CONSOLIDATED DURING PREVIOUS
COLLABORATIONS AND WHICH SUSTAIN IT. ACCOMPLISHMENT OF THE OBJECTIVES OF THIS
PROJECT CONSTITUTES A SCIENTIFIC CHALLENGE FOR ANY SCIENTIFIC TEAM AROUND THE
WORLD.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects