BrainMap

Mr. Cristian Rasvan Baicus

PhD

Professor - UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"

Other affiliations

Professor - SPITALUL CLINIC "COLENTINA" BUCURESTI (Romania)

Researcher | Teaching staff

Web of Science ResearcherID: C-3355-2008

Curriculum Vitae (19/03/2020)

Expertise & keywords

An integrated approach to cardiovascular function for outcome prediction in severe aortic stenosis: the role of exercise echocardiography Call name: Exploratory Research Projects - PCE-2012 call
PN-II-ID-PCE-2012-4-0560 2013 - 2016

Role in this project: Key expert

Coordinating institution: UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA

Project partners: UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO)

Affiliation: UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO)

Project website: http://www.euroecolab.ro/Proiecte/Proiecte.html

Abstract:

Calcific aortic stenosis (AS) is the most common valvular heart disease, with an increasing prevalence due to the ageing population. Management of asymptomatic patients (pts) with severe AS is still under debate due to difficulties in accurately balancing the risk of intervention versus that of watchful waiting. Based on pathophysiological data we hypothesised that a comprehensive assessment of arterial stiffness, left ventricular (LV) and left atrial (LA) function at rest and during exercise could identify markers of increased risk in asymptomatic severe AS.
Using exercise echocardiography, we aim to assess for the first time the predictive value of exercise-induced response of parameters of LV systolic and diastolic function (LV myocardial deformation parameters, LV untwisting, E/E’ ratio, BNP serum level) and LA functional reserve in asymptomatic pts with severe AS. We also intend to perform a comparative assessment of vascular and cardiac function in asymptomatic versus symptomatic pts with severe AS and preserved LV ejection fraction and to assess the impact of aortic valve replacement on different parameters of cardiac function in symptomatic pts with severe AS evaluated at rest by state-of-the-art imaging techniques (carotid e-tracking, tissue Doppler/speckle tracking echocardiography, 3D-echocardiography). Incorporating these new parameters into a risk score for outcome prediction in asymptomatic severe AS may provide an useful tool for clinical decision making.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator	Download (170.7 kb) 14/04/2016
List of research grants as partner team leader	Download (109.02 kb) 14/04/2016
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects	Download (49.21 kb) 05/11/2017