BrainMap

Mrs. Dana Gingasu

Ph.D.

- INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Researcher

Web of Science ResearcherID: Author ID: 6504495733

Curriculum Vitae (03/04/2025)

Expertise & keywords

INNOVATIVE MATERIALS AND PROCESSES FOR SELECTIVE HEAVY METALS REMOVAL FROM WASTEWATER Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0418 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU INGINERIE ELECTRICA ICPE - CA BUCURESTI (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); KEMCRISTAL SRL (RO); INSTITUTUL DE STUDII SI PROIECTARI ENERGETICE S.A. (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://hapchitmag.chimie.upb.ro

Abstract:

The project entitled Innovative Materials and Processes for Selective Removal of Heavy Metals from Wastewater is included in the global concerns of humanity to have access to drinking water resources in the conditions in which water sources are becoming increasingly polluted. The most important anthropogenic sources of heavy metals are wastewater from various industries such as: electroplating, leather industry, textile industry, dyes industry, mining industry. Due to the fact that heavy metals are not biodegradable and they can be bio(accumulated) in living tissues, they can enter directly or through the food chain in human bodies, most of them being toxic, thus their removal from wastewater is currently imposed by legislative rules. Technologies to remove heavy metals from wastewater include precipitation, ion exchange, electrodeposition, membrane processes, sorption, sequestration by cementation. All these technologies have advantages and disadvantages (high operating costs, and for some of them obtaining sludges with heavy metals that will be stored and thus will determine soil pollution, or they will require further processing).

The project’s aim is to develop novel materials (nano- and micro-scale) with high selectivity for removal/retaining heavy metals from wastewater by solid phase synthesis, precipitation from aqueous solutions, and non conventional techniques such as sol-gel and microwave-assisted synthesis. The products obtained will be also as powder, beads, micro/nanospheres (hydroxyapatite, magnetite and chitosan), and compounds with complex structures like chitosan composites, chitosan cross-linked with glutaraldehyde, magnetite nanoparticles functionalized with organosilane and chitosan. The main purpose is to increase the selectivity, sorption capacity, durability and stability in acid environments, specific to wastewater.

Materials obtained will be tested in heavy metals (Pb(II), Cu(II), Ni(II) si Zn(II)) removal/retaining processes from synthetic solutions and industrial wastewater in order to identify the material with high selectivity and sorption capacity. There will be performed batch and continuous tests to establish the influence of factors (contact time, stirring speed, pH, size of adsorbent particles, height of adsorbent bed, metal ion concentration in the initial solution/wastewater, competition with other metal ions) on the sorption process. The kinetic and thermodynamic studies will be performed to establish the mechanisms involved in sorption process for industrial technology development.

Some of residual products resulted can be used in different industrial sectors such as: ceramics industry, building materials industry, and the others can be recovered by desorption processes and reused in other sorption processes. Materials and technologies proposed can be considered as main components of sustainable development of society due to the fact that they improve population health, protect the environment, reuse and integrate wastewater in natural and industrial cycles, create new jobs for young researchers, but also for people in urban areas, especially those affected by industrial pollution. The results obtained by the work performed in this project will be disseminated. The most relevant results will be used to apply for a patent proposal and for their industrial implementation. Research and development works will be based on moral and ethical principles according the deontology (Law 206/2004) endorsed by all partners in the consortium.

New complex combinations of some lanthanides with antitumoral properties and their use in design and development of new drugs Call name: Joint Applied Research Projects - PCCA-2011 call, Type 1
PN-II-PT-PCCA-2011-3.1-0913 2012 - 2016

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI

Project partners: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://ncpri.ro/proiecte/antineomed/index.php sau antineomed.ncpri.ro

Abstract:

Cancer, considered to be the “century scourge”, is one of the diseases with the highest death rates around the world.

One of the major concerns of researchers in pharmaceutical and medical field is to discover new molecules and new drugs to fight cancer more effectively than existing.

The latest approach to developing antitumor drugs, at an international level, focuses on enriching the studies on the metallic compounds of the therapeutically active organic structures. Those compounds should have a better pharmacological activity due to the synergic effect of the ligand and the metallic ion or due to the complex’s self-included activity.

Being in agreement with the general world-wide interest, this partnership project sets sights on making the most of the acknowledged antitumor potential of the lanthanides by designing new therapeutically active molecules that have never been recorded in any pharmacological databases. Thus, the objective is to obtain new complex combinations of simple and mixed ligands - benzothiazine-carboxamides (oxicams) or polihydroxyflavones (flavonols) – that would further be used to conceive and develop new drugs. Oxicams are especially recognized for their anti-inflammatory activity, as well as anitumoral, while flavonols – which are natural compounds – are known for their powerful antioxidant, antibacterial and antitumor properties. It is expected that the new complex combinations, as well as the resulting original drugs, would comprise the cumulative antitumor/antiinflammator/antioxidant potentials of the reactants, thus creating new mechanisms of action with increased efficiency in antitumor therapy.

This project sets out to conceive and then fully develop original drugs, starting from the chemical synthesis of new pharmaceutically-active substances that have never been cited in any databases, to the including into pharmaceutical doses and the elaboration of all the documentation required for setting a product out on the market.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects