BrainMap

Florentina Violeta Maxim

Dr.

Researcher - INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Other affiliations

- PAUL SCHERRER INSTITUT (Switzerland)

Researcher

Dr. F. Maxim is a Senior Scientist at the “Ilie Murgulescu” Institute of Physical Chemistry, Bucharest, Romania. She received her BSc and MSc degrees in Chemistry from the University of Bucharest. In 2010, she obtained her PhD title in Materials Science and Engineering from the University of Aveiro, Portugal. Between 2015 - 2019 she activated as postdoctoral fellow at LBK, ENE Division, Paul Scherrer Institute, Villigen PSI, Switzerland. As project leader, she managed to attract more than 400k Euros by two grants of the Romanian Ministry of Research, Innovation and Digitalization. Her research experiences are on metal oxides thermodynamics, synthesis, and materials characterization, being specialized in electron microscopy. In present, her research activity is focused on design and development of materials used in supercritical water technologies. Her publications in Nature Communications (2019) and Advanced Science (2021) are reporting pioneering work in the supercritical water field.

Web of Science ResearcherID: https://publons.com/researcher/C-2924-2011/

Curriculum Vitae (28/04/2025)

Expertise & keywords

CARBON SUPPORTED METAL OXIDES PRODUCED BY SUPERCRITICAL WATER IMPREGNATION METHOD Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-1241 2021 - 2023

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Project partners: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://www.icf.ro/pr_2020/APASUPER.pptx

Abstract:

The APASUPER project deals with preparation, characterization and testing supported metal oxides to be used as sorbent materials in separation processes carried out under supercritical water (scH2O) conditions. The one-step preparation method (continuous scH2O impregnation of metal oxides on carbon) is here presented as novelty. It will be developed by combining the available knowledge with the very recent information on the coexistence of gas- and liquid-like phases, observable when scH2O interacts with porous carbon (Maxim et al. Nat. Comms. 2019). The project has both an exploratory and an inter-disciplinary character and aims to be the first step towards long-term collaboration between the Institute of Physical Chemistry, Romania (host) and Paul Scherrer Institute, Switzerland (main partner). During the research stages at the Swiss partner, cutting-edge research will be performed at PSI’s large-scale facilities using neutron/synchrotron radiation. In this way, the project will contribute to spread the excellence within Europe by bringing the scH2O science to the attention of the Romanian research community. The materials prepared, characterized and tested during this project might contribute to the implementation at large-scale of the promising scH2O technologies, which can in turn help to achieve the 6th (clean water and sanitation) and the 7th (affordable and clean energy) Sustainable Development Goals on UN’s new 2030 agenda.

Research of the bone substitution with biocomposite materials processed by powder metallurgy specific techniques Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-2094 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA DIN CRAIOVA

Project partners: UNIVERSITATEA DIN CRAIOVA (RO); TEHNOMED IMPEX CO S.A. (RO); SPITALUL CLINIC DE URGENTA " BAGDASAR-ARSENI " (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://mecanica.ucv.ro/Cercetare/BONY/index.html

Abstract:

The research proposal is entitled “Research of the bone substitution with biocomposite materials processed by powder metallurgy specific techniques”, acronym BONY. Its general objective is to obtain advanced biocomposite materials, based on hydroxyapatite (HAP) matrix reinforced by Ti-based powder particles. The osseointegration process is accelerated by the natural organic esters of Bor, as a component of the biocomposite powders mixture. The applications aim the bone substitution by small-sized reconstructions for skull and vertebrae body.

BONY project matches the priority domain 7 (Materials, innovative processes and products), research area 7.1 (Advanced materials), research topic 7.1.6 (Advanced materials and biomaterials for life quality improvement (health, sport, education etc.)).

The project relevancy is underlined by the necessity to elaborate bone implants for skull and vertebrae by advanced biocomposites, with improved osseointegration capacity to the adjacent native bone tissue. Also, the technical and economical savings are important as far as the processing technologies concern.

The BONY project results are:

1. the innovative biocomposite material as bulk product for vertebral implant processed by micro-injection moulding technique;

2. the innovative biocomposite material as coating for skull implant processed by MAPLE technique on Titanium substrate;

3. the innovative material and method to accelerate the osseointegration process of the bone implants.

The innovative/original aspects of the BONY project are represented by:

- the innovative combination of metallic and ceramic powders, micrometric and nanometric sized. The advanced sintering techniques as well as the coating ones provide hybrid structured biocomposites that assure improved physical, mechanical, technological and biochemical properties relative to the native bone.

- using, for the first time, of the micro-injection moulding technique, to process complex shaped and small sized bone implants;

- the original an innovative application of MAPLE coating technique to process hybrid biocomposite coatings on Ti substratewith similar properties to the bulk biocomposites type.

- the original method to accelerate the osseointegration process by using special additives, Bor natural organic esters, in special technological procedures.

The BONY implant biocomposites provide the following advantages as follow: resorbability, geometrical stability, improved lifetime, micro-machinability for final geometrical adjustments, able to be processed as complex shapes and small dimensions, improved osseointegration.

The impact of the project results may be evaluated from the following points of view: scientifical (innovative biocomposite materials), technological (suitable processing technologies to the implants shape and size), research human resources training (young Ph.D. students or graduated, members of consortium), economical and social (improving the patient’s life quality).

The quality, expertise and research, innovative and entrepreneur skills of the BONY partners assure the successful fulfilment of the project objectives. The BONY consortium is represented by: CO – University of Craiova (UCV); P1 - S. C. Tehnomed Impex Co S.A., Bucuresti (IMM); P2 – The Emergency Clinic Hospital „Bagdasar-Arseni”, Bucharest; P3 – The National Institute for Laser, Plasma & Radiation Physics (INFLPR), Bucharest ; P4 – « Ilie Murgulescu » Institute of Physical Chemistry of the Romanian Academy (IPC), Bucharest ; P5 – Politehnica University of Bucharest (UPB).

Drug delivery systems based on mesoporous inorganic matrix Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-0437 2012 - 2016

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); POLIPHARMA INDUSTRIES S.R.L. (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://www.chim.upb.ro/uploads/cafe/pages/mesodrug.html

Abstract:

The project Drug delivery systems based on mesoporous inorganic matrix approaches a very complex research in a topic of great interest for the human health and will be execute by a consortium. The complex project is structured in 3 stages as modules, with a total duration of 31 months.

The main challenge of this proposal is to convert some injectable cytostatic drugs in oral targeted drug delivery systems with controlled release. Besides this, another challenge of the project is to perform a complete investigation of interactions between inorganic matrix and pharmaceutical active compounds by various techniques, the interactions between both obtained drug delivery systems (DDS) and inorganic carriers with cells and cellular membrane, as well as the drug release form the obtained DDS in biological synthetic fluids according to pharmaceutical standards. None of the participant institution is able to complete alone this multidisciplinary, complex research. The consortium, consisting in two prestigious universities, University Politehnica of Bucharest (coordinator), “Carol Davila” University of Medicine and Pharmacy, together with Institute of Physical Chemistry - Romanian Academy and S.C. Polypharma Industries Sibiu the end user, can fulfill these challenges.

It is proposed to investigate DDS based on three type mesoporous carriers, with adequate surface modification, silica, titania and ceria, as well as magnetic core-shell mesoporous silica. The DDS efficiency will be studied via cell viability and Reactive Oxygen Species (ROS) production, as well as by United Pharmacopeia Standards (UPS).

Expected results should be of high scientific level and could be valorized in valuable publications in high ranked journals, one patent and technology transfer towards the end user.

nanoPerovskites in one-dimension: synthesis, structure, properties Call name: Projects for Young Research Teams - TE-2011 call
PN-II-RU-TE-2011-3-0160 2012 - 2015

Role in this project: Project coordinator

Coordinating institution: Institutul de Chimie Fizica Ilie Murgulescu

Project partners: Institutul de Chimie Fizica Ilie Murgulescu (RO)

Affiliation: Institutul de Chimie Fizica Ilie Murgulescu (RO)

Project website: http://www.icf.ro/pr_2011/1DnanoPEROVSKITES.htm

Abstract:

Modern technology demands nanostructures. Recently, one-dimensional (1D) nanostructures, including nanowires, nanotubes and nanorods, have been considered as the most promising building blocks for nanoscale electronic and optoelectronic devices. Worldwide efforts in both the theory and the experimental investigation of growth, characterization and applications of 1D nanostructures have resulted in a mature, multidisciplinary field. Within this context, the main aim of this project is to elucidate the correlations between dimensionality and properties of some 1D nanostructured complex oxides with perovskite structure obtained by bottom-up chemical methods. The synthesis of some ferroelectric and multiferroic perovskites type nanomaterilas will receive a special focus and the process optimization will be guaranteed by exhaustive characterization based on electron microscopy techniques. The electrical (ferroelectric, multiferroic) and thermodynamic properties of the resulted 1D nanomaterials will be investigated in order to establish the size-shape-properties connection to further applications.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects