BrainMap

Gheorghe Borodi

Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Researcher

After graduating from the Faculty of Physics in Cluj, he worked at the Research Center for Electronic Components Baneasa-Bucharest. After which he transferred to the National Institute of R&D for Isotopic and Molecular Technologies. The most important scientific concerns are related to the determination of the crystal structure of single crystals and crystalline powders. He also approached most of the methods of characterizing crystalline materials by X-ray diffraction on powders. Other concerns were related to the application of Small angle X-Ray scattering to the characterization of materials, diffraction on amorphous structures and diffraction on thin films. In the computational domain, he was concerned with intermolecular interactions, Hirshfield surfaces and lattice energy. He prepared and characterized structurally, spectroscopically, in terms of solubility and stability numerous solid forms.

Web of Science ResearcherID: D-5029-2011

Curriculum Vitae (27/07/2026)

Expertise & keywords

Innovative strategies for safe production of advanced materials based on multifunctional ceramic and metallic nanoparticles for medical applications Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-1910 2021 - 2023

Role in this project:

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO)

Affiliation:

Project website: http://www.chem.ubbcluj.ro/romana/ANEX/cf/pcas/INA_MAT/index_INA_MAT.htm

Abstract:

INA-MAT project is focused on three topical scientific fields in current nanomedici ne related to the use of metallic nanoparticles, NPs, of various controlled size, shape, surface area and surface structure modified by complexation with drugs: (1) for targeted delivery of anti-cancer drugs, ACD, to cervical and bone cancer, and of anti-microbial compounds, AMC, targeted to bone infections. In this regard, metallic NPs, as gold nanoparticles, GNPs, are functionalized with various ACD, resulting GNPs-ACD nano-complexes targeted to cancer cells. Further, GNPs and silver nanoparticles, AgNPs, are functionalized with anti-microbial compounds AMC, resulting GNPs-AMC and AgNPs-AMC, nano-complexes. (2) The combined metallic NPs-drug complexes with hydroxyapatite NPs, HAP, or with multi-substituted HAP, ms-HAP, used as carriers for metallic nano-complexes, are prepared leading to innovative nanomaterials for local drug delivery to bone disorders and bone regeneration. (3) The GNPs-AMC and AgNPs-AMC nano-complexes and ceramic NPs, jointly embedded into polymer matrix, result in nano-composites for sustained drug release at the place of action, enhancing local drug delivery to bone infection, especially osteomyelitis that affects bone marrow, too. The INA-MAT project is focused on the elucidation of various physicochemical properties of each innovative nanomaterial developed and on determination of kinetics of interaction of innovative advanced nanomaterials with target tissue.

Stability of the conjugated sulfonamides MOFs used as electrode materials for lithium-ion batteries Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-0824 2021 - 2023

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation:

Project website: https://www.itim-cj.ro/PNCDI/pce22/index.html

Abstract:

A broad variety of organic compounds have been proposed and studied as electrode materials for batteries over the last decades. However, to date, none of these chemistries are practically suitable for ready-to-assemble Li-ion battery applications. The conjugated sulfonamides (CSA) organic lithium ion cathode materials proposed recently pave the way to new avenues in the field or organic batteries; in particular, the MOFs fabricated using the CSAs have the potential to reach technological maturity..

Our investigations are focus on the study of the stability for a class of 25 structure of type CAS-MOF under cyclic voltametry. Chemical stability will be investigated by analyzing relevant information produced by density functional theory: Bader charges and bond-orders in different redox states, in bulk phase as well as in the molecular form; in this late case, we’ll take into account the presence of solvents. The thermodynamic stability will be investigated via the vibrational entropy of the CSA-MOFs as a function of temperature. Calculations will be done in two parts: ab-initio molecular dynamics, and the analysis of the atomic speeds by Fourier transform in the second part. The results are the vibrational density of states and thermodynamic potentials. The effect of our investigation is to speed up the progress in the field of CSA-MOF organic electrodes by using accurate predictions to narrow the spectrum of systems to be investigated in detail as cathode material.

Elaborating Complex Methodologies Regarding the Attribution and Authentication of Medieval and Early Modern Paintings Belonging to the National Cultural Heritage Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0812 2018 - 2021

Role in this project:

Coordinating institution: INSTITUTUL DE ISTORIA ARTEI "G.OPRESCU"

Project partners: INSTITUTUL DE ISTORIA ARTEI "G.OPRESCU" (RO); UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA (RO); UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); ACADEMIA ROMANA FILIALA CLUJ (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: https://idart.utcluj.ro/

Abstract:

The project aims to develop a multi-criteria method for the authentication and attribution of paintings (murals, on wood, on canvas) from the medieval and early modern periods belonging to the national cultural heritage. The proposed semi-automatic method is based on a decision-support system platform (IDART) developed within the project, which is built using a "convergent approach to truth" principle. The project relies on trans- and interdisciplinary tools: art historical, physical-chemical, iconographic and theological analysis, database, programming and image processing. The IDART platform consists of a database that includes metadata obtained from art documentation, photography -HDR, VIS, light grazing, IR, UV-, sampling and in-situ physical-chemical analysis of the support and ground layers as well as of the colors and the varnishes using XRF, FTIR, Raman, LC and GC-MS techniques. For each image that is to be authenticated we shall define several regions of interest (ROI) used for the automatic search in other artworks from the database which also share the common details defined in the ROI. The process of identifying the common elements of two or more paintings takes place in several stages using various filters which limits the target group so that in the final stage they can be analyzed by the art historian in order for her to finally be able to authenticate and attribute them. Image processing will use algorithms derived from the Cross Correlation method that can be also applied to photographs not belonging to the visible spectrum. For the development of the image processing algorithms we shall use signed paintings, while other works attributable to the same painters will be used for validation. The final result of the project will be suitable not only for academic use, but it can also be most valuable to the institutions responsible for the preserving and/or promoting our cultural heritage, private collectors and other professionals in the art market.

Improving "eco-friendly" ceramic blocks fabrication technology Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0203 2016 - 2018

Role in this project:

Coordinating institution: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA

Project partners: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); CEMACON - S.A. (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: https://constructii.utcluj.ro/files/2016-2017/bridge_grant/

Abstract:

The project is set to improve the ceramic material produced by CEMACON Zalau Company, by optimizing the existing technology of fabrication in order to reduce the energy demand in operation and implicitly the embodied energy in nZEBs.

The target is to improve both, the thermal characteristics and cost, by adding recycled materials and pore generating additives into the fabrication recipes. In the first stage, the basic raw materials that compose the ceramic masonry blocks will be analyzed from microstructural point of view. In the second stage, the microstructural, thermal and mechanical characteristics of some reference samples produced by CEMACON Company following the existing fabrication recipes will be defined. In the third stage the existing recipes will be optimized and the newly obtained products will be analyzed from thermal and physical-mechanical point of view. The improvement of quality control will be targeted by developing a methodology able to identify the structural deficiencies of the ceramic blocks through synchronous thermography detection. In the last stage, cost-benefit and environmental impact analyses will be performed, following the anti-seismic design regulations and the nZEB standards.

Revival of an old drug by crystal engineering: development of improved ketoconazole based antifungal products Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-1521 2017 - 2018

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://www.itim-cj.ro/pncdi/ketcrys/index.htm

Abstract:

The goal of the proposed project is to assess the market potential of two co-crystal solid forms of ketoconazole (KET) with fumaric acid (FUM) and p-aminobenzoic acid (PABA) coformers, as APIs with improved properties in terms of solubility / antifungal activity. The 100-fold increased solubility of KET-FUM compared with commercial KET indicates his pharmaceutical potential for oral drug therapy by reducing the administered dose. On the other hand, KET-PABA with only 10-fold increase solubility, increase antifungal activity and due to its sunscreen coformer has pharmaceutical potential for topical use, especially during summer time. The project results will complete the preliminary preformulation information of KET-FUM and KET-PABA already reported by our research group (protocol for co-crystallization process at small scale – milligrams, solubility and dissolution rate, thermal analysis, FT-IR and antifungal activity for both solid forms and structural characterization of KET-FUM) with common and specific studies/assessment (compatibility with pharmaceutical excipients for KET-FUM – oral therapy; crystal structure characterization for KET-PABA, in vitro and in vivo biocompatibility assessment for both crystalline forms). We will also develop protocol for co-crystallization process at large scale (grams) necessary in pharmaceutical industry for developing a successful industrial co-crystallization process. This research will raise the technology readiness level from TRL2 to TRL4 for KET-FUM and KET-PABA crystalline forms. For KET-PABA (targeted for topical therapy) we will initiate a patenting strategy.

The improvement of the manufacturing technology of lead-acid batteries to be used for start-and-stop automobiles Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1226 2014 - 2017

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA BABES BOLYAI (RO); ROMBAT S.A. (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://www.itim-cj.ro/PNCDI/rombss/

Abstract:

We propose a methodology for the improvement of fabrication technology for the positive electrodes used as components in the lead-acid batteries produced at sc rombat sa . The final goal of our consortium is to improve the current technology used by industrial partner for fabrication of the batteries to be used for start-and-stop automobiles (i.e . To satisfy the j240 – sae and en 50342-6 quality tests) . The proposed approach is designed for the optimization of the scientific and technological steps involved in the fabrication of positive electrodes . It integrates the fundamental knowledge obtained from ab initio calculations, synthesis of new chemical compounds, fabrication of new alloys and structural characterization of the materials used to fabricate the electrode, at both nanoscopic and mesoscopic scale . The key element for the integration of all these activities is the fabrication and characterization of functional prototypes by the industrial partner.

The main problem to be solved is to control the corrosion of the positive electrode during the charge-discharge cycles, imposed by the requests of the start-and-stop technology . The solutions proposed by our consortium are: (i) fabrication of new alloys to be used for the production of the metallic grid that support for the active mass of the electrode (ii) improving the fabrication technology of the metallic grid (iii) improving the electrochemical properties of the active mass by new fabrication technology and by the use of new additives to the active mass. We note here that for the negative electrode as well as for the electrolyte the standard products fabricated by sc rombat sa will be used . The project’s goal will be achieved by using a feed-back loop: the design of materials and the fabrication steps involved by each prototype will be refined by successive fabrication of the prototypes that will gradually incorporate the information produced by each partner . At each step of our methodology the full characterization of the electrochemical and structural properties of the materials and prototypes already fabricated will be used as starting point for further refinement of the fabrication technology . A continuous exchange of data between the research Institutes and the industrial partner is foreseen for the whole duration of the project . This will allow us to tune the results obtained in the laboratory with those produced in industrial conditions . At project’s term we will discuss the technological steps needed for the implementation of the results by using the infrastructure available at sc rombat sa.

Security paper with imbedded magnetic nanoparticles Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0560 2014 - 2017

Role in this project:

Coordinating institution: ACADEMIA ROMANA FILIALA TIMISOARA

Project partners: ACADEMIA ROMANA FILIALA TIMISOARA (RO); CEPROHART S.A. (RO); ROSEAL S.A. (RO); DATRONIC-NCIP S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA POLITEHNICA TIMIŞOARA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://vsocoliuc.wordpress.com/projects/nanomagsecuritypaper/

Abstract:

Document forgery is a criminal activity that causes billion dollar losses each year worldwide. Security paper is among the most important ingredients used in the fight against the forgery of private or public documents. The continuous diversification and sophistication of the paper securing techniques is one of the most important ways to erect fences against forgery attempts. The NanoMagSecurityPaper project aims to expand the diversity of high tech means for paper securing. The project’s strategic objective is to bring magnetic security paper on the security paper market. It is estimated that the Romanian security paper market alone will demand for tens of tons of magnetic security paper each year.

NanoMagSecurityPaper brings in the idea to obtain magnetic security paper by dispersing superparamagnetic nanoparticles in the wet cellulose pulp. The superparamagnetic paper thus obtained gets the functionality of security paper only together with appropriate validation methods and instruments. In order to meet this goal, joint applied research from the following three fields is necessary: 1. paper making, 2. magnetic nanoparticle/composite synthesis, and 3. magnetic sensing and validation. In order to meet the highest security standards, the authenticity checking procedures should make possible both a fast, handy and reliable first instance validation, and a sophisticated, albeit laborious, high security level validation. The NanoMagSecurityPaper will elaborate and test methods to produce high security level magnetic paper, by embedding in the paper composition magnetic nanoparticles and, for white color paper, magnetic composites. A handy and high sensitivity first instance validation method and instrument will be developed.

NanoMagSecurityPaper will achieve its objectives by transferring fundamental and applied knowledge on magnetometry, magnetogranulometry, magnetic sensing and magnetic nanoparticle/composite synthesis, from three Romanian academic institutions to three Romanian industrial partners: SC CEPROHART SA - security paper producer, SC ROSEAL SA - magnetic nanoparticle/composite producer, and SC DATRONIC-NCIP SRL – electronic equipment producer. NanoMagSecurityPaper will provide high-tech added value to the product portfolio of the consortium industrial partners, as well as a deeper scientific knowledge transfer expertise to the academic institutions of the consortium.

NanoMagSecurityPaper will also open means for the development of securitization techniques for a wide range of diamagnetic materials like paints, textiles, polymeric composites, and others.

Development of new tools and smart composites based on advanced nanotehnology for medical applications Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-0723 2012 - 2016

Role in this project:

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); BENEROM CONSTRUCT S.R.L. (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://chem.ubbcluj.ro/romana/ANEX/cf/pcas/proiect%20dontas%20files/index%20dontas.htm

Abstract:

DONTAS project presents the research, development and innovation of new tools, like surgical methods and techniques by using metal implants coated with smart composite layers based on advanced nanotechnology for medical applications. More specific, nanostructured phosphates (nanoPHOs), such as nano hydroxyapatite (nanoHAP) incorporating different additions of silicon as an osseopromotive agent, as well as magnesium and zinc requested for bone metabolism are synthesized and structural, morphological and biological characterized. Further smart composites, made of said nanoPHOs incorporated into natural polymers (collagen type I and/or chitosan) are developed to mimic the characteristics of natural bone. In addition, nanoPHOs are incorporated into synthetic polymers (PMMA or poly-Bis-GMA) for comparison with the above ones. Our preliminary results indicate a remarkably difference among morphologies of various DONTAS composites ranging from particulate matters to fibers mineralized with nanoPHOs. Also, metal implants are realized by a strong cooperation in DONTAS consortium, formed of two prestigious universities and two important national institutes, as well as a small and medium sized enterprise (SME). The metal implants are advanced processed to reach the surface characteristics to be well osteo integrated in bone. Furthermore, the surface of implants is functionalized by coating with DONTAS composite layers to efficiently promote the bond of the implant to the bone. This inventive project tackles the bioactivity of the above new composites assembled as scaffolds on implants (rods, intramedullary rods or plates), which will be thoroughly examined in cell cultures of osteoblasts. DONTAS surgical tools and smart composites will have large medical applications for repairing and replacement of bone in orthopedic surgery and in reconstructive medicine.

Issues and challenges for hydrogen storage in composites with metal-organic frameworks Call name: Exploratory Research Projects - PCE-2011 call
PN-II-ID-PCE-2011-3-0350 2011 - 2016

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Tehnologii Izotopice si Moleculare

Project partners: Institutul National de Cercetare-Dezvoltare pentru Tehnologii Izotopice si Moleculare (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Tehnologii Izotopice si Moleculare (RO)

Project website: http://www.itim-cj.ro/PNCDI/idei350/Home.htm

Abstract:

Metal–organic frameworks (MOFs), a new class of crystalline materials exhibiting extremely high porosity, attracted attention as hydrogen-storage materials, similar to the best activated carbons at 77K. However, for applications in transportation a high H2 sorption capacity at ambient temperatures with low adsorption/desorption enthalpy are required. The promising results for room temperature H2 adsorption on MOFs composites with Pt/activated carbon recently reported were assigned to ‘‘spillover” effect but the controversy raised due to contradictory literature results is still open and needs to be solved due to its possible high impact on hydrogen storage.

The goal of the project is to assess the enhanced hydrogen adsorption reported in literature and to find new materials and methods to improve the H2 storage in solid state materials. New approaches for building the intimate contact at the interface of MOF with metal/support catalyst will improve the knowledge of the routes and methods with positive effects on hydrogen adsorption by MOFs based composites. Systematic studies will be performed on MOF/catalyst composites, employing alternative and complementary methods, with emphasis on: controlled ball-milling procedure, influence of the catalytic metal (Pt, Pd, Ni) or support, direct synthesis of different MOFs on catalyst, validation of hydrogen uptake measurements, identification of the major factors implied in the hydrogen transfer at the MOF/catalyst interface.

Modern high-troughput methodologies for obtaining and characterizing new solid forms of pharmaceutical compounds Call name:
POSCCE ID 536 2010 - 2014

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://www.itim-cj.ro/pos/htpharma/

Abstract:

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects