BrainMap

Mrs. Ionela - Cristina Petcu

Medical Engineer

Research engineer electrotechnics/biomedical - CENTRUL INTERNATIONAL DE BIODINAMICA

Researcher | Student | PhD student

Curriculum Vitae (23/06/2021)

Expertise & keywords

Accurate sensing platform for VOC detection in air quality control systems of smart cities Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-3090 2022 - 2024

Role in this project:

Coordinating institution: CENTRUL INTERNATIONAL DE BIODINAMICA

Project partners: CENTRUL INTERNATIONAL DE BIODINAMICA (RO)

Affiliation:

Project website: https://www.biodyn.ro/PROJECTS/AQVOC/AQVOC.html

Abstract:

Project AQVOC aims to improve the capabilities for air quality monitoring in smart city applications by development of a fast, sensitive and reliable device for detection of outdoor and indoor Volatile Organic Compounds (VOCs) based on the Magneto-Optical Surface Plasmon Resonance (MO-SPR). The validated demonstration model will be based on the SPR technique, magnetically augmented, towards a product that can be integrated in the market. The device will use available modular benchtop MOSPR equipment previously developed by our team combined with our portable SPR platform with imaging capabilities, patents pending. The sensitive area will consist in an array of spots of gas sensitive polymers and metallic oxides providing a specific “fingerprint” after interacting with individual VOCs. Data will be collected and analyzed using the Principal Component Analysis (PCA) approach to extract relevant data regarding the nature and quantity of the target VOC. The project starts from TRL2, and is expected to reach TRL 4 - the validation of the components and of the detection platform in the laboratory environment. Validating the platform will make an easier task for a future development towards integrating the whole setup into a complete model. After project completion, the AQVOC platform is intended to be further developed and checked to successively reach the next TRLs for being produced and reach the market. The project activities are sustained by a well-equipped infrastructure and a multidisciplinary team of researchers with expertise in all needed areas: modelling & data analysis, instrumentation and software development, thin film deposition and characterization, micro-fabrication.

High resolution multiparametric dynamics at single cell level: virus detection by assessing cellular response to viral exposure Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-2432 2021 - 2023

Role in this project: Key expert

Coordinating institution: CENTRUL INTERNATIONAL DE BIODINAMICA

Project partners: CENTRUL INTERNATIONAL DE BIODINAMICA (RO)

Affiliation: CENTRUL INTERNATIONAL DE BIODINAMICA (RO)

Project website: https://www.biodyn.ro/PROJECTS/DYNASCOPE/dynascope.html

Abstract:

Cellular-based sensing platforms face serious challenges before enabling full realization of the concept of “cell sentinels” against biological threats (in particular against viral infections, as stringently called into action given the SARS Covid 2 pandemics).

Grounded on the PL expertise and the resources of the International Centre of Biodynamics team, DynaScope advances a sensing platform for quantification of viral (particles) entry in model cells and characterisation of cellular dynamics associated with viral replication progress. The biosensing concept is based on label-free monitoring the dynamics of electrical, morphological, structural and metabolic properties of relevant intracellular structures upon viral exposure, at high spatial and temporal resolution. We achieve this through: (a) multiplexed/multiparametric assays, (b) use of bioengineered cells (c) analysis of time-lapse dynamical data. Via a broad biotechnology/ bioengineering effort we integrate phase (via SPR/QPI) and electrical impedance information within an AC electric field actuated plasmonic based EIS (P-EIS) microscopy setup. The envisaged platform will provide accurate, dynamic electro-optical (quantitative phase) maps of cellular changes corresponding to physiological states of both single cells (ACE2 HEK modified cells) and cell ensembles. The unique detection characteristics of the DynaScope are essential for applications in the fields of cell signalling, drug screening and hazard evaluation.

Automated Analytical Platform for Rapid Antimicrobial Susceptibility Testing Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4932 2020 - 2022

Role in this project: Key expert

Coordinating institution: CENTRUL INTERNATIONAL DE BIODINAMICA

Project partners: CENTRUL INTERNATIONAL DE BIODINAMICA (RO)

Affiliation: CENTRUL INTERNATIONAL DE BIODINAMICA (RO)

Project website: https://www.biodyn.ro/PROJECTS/AutoAST/autoast.html

Abstract:

The scope of the proposed project is the development and validation of an Automated Analytical Platform for Rapid Antimicrobial Susceptibility Testing (

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