BrainMap

Mr. Laurentiu Irimia

IDT

- DELTAROM SRL

Researcher | Technician

Curriculum Vitae (01/10/2021)

Expertise & keywords

Innovative multifunctional, bioactive topical formulation for the management of malignant wounds Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-2193 2022 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation:

Project website: https://bios.unibuc.ro/Proiecte/proiect-pn-iii-p2-2-1-ped-2021-2193.html

Abstract:

Malignant fungating wounds (MFW) are incurable, severe, and debilitating conditions normally occurring in the last (six) months of oncologic patient’ life, affecting the overall quality of life and requiring appropriate palliative care to alleviate pain and suffering. MFW’s microbiome may influence the development and severity of wound symptoms, causing foul odors, peri-wound skin damage, inflammation, and ultimately, delays in the healing proliferative phase. ARGOS project is implemented by a consortium of two research institutions and one company with previous experience in developing collagen-based pharmaco-cosmeceutic products and is aiming to develop an innovative multi-purpose, bioactive topical formulation to assist the physical management of malignant fungating wounds, by addressing the microbiome-related symptoms such as pain, odor, and exudate. The proposed solution is based on collagen and inorganic - gold, silver and magnetic – nanoparticles functionalized with plant-derived bioactive compounds (such as polyphenols contained in Chelidonium majus L. and Tamarix gallica extracts, with previously demonstrated antioxidant, antimicrobial, antiproliferative, antiviral and immunomodulatory activity). Therefore, the main novelty of the proposed solution is that it provides not only a wide antimicrobial effect, but also anti-cancer activity and pro-healing properties on the site of malignant wounds. The physico-chemical, mechanical and biological properties of the collagen-based optimized product will be validated by standard protocols and the technological scaling documentation and argumentation of the investments required for in vivo tests will be elaborated (TRL4).

SYNERGICSTIC ACTIVES SYSTEMS FOR REGENERATIVE COSMETICS Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0303 2022 - 2024

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation:

Project website: https://www.sanimed.ro/proiect-grace_36.html

Abstract:

The GRACE project aims to obtain and characterize a range of integrative products, designed to regenerate the epidermis affected by superficial lesions, solar radiation, radiation therapy, or bedsores, using specifically functionalized hydrogels with complexes of inclusion of active ingredients in host molecules. These supramolecular complexes will represent the innovative component in the formulation of a new range of products with applications in the field of regenerative cosmetics. In concrete terms, the GRACE project aims to obtain a range of 3 products: single-dose hydrogel (for superficial lesions), cream gel (for skin affected by radiation) and cleansing gel (for gentle debris removal and cleaning of superficial lesions). In this sense, the project will stimulate the investment in research - technological development from the beneficiary company, as well as the consolidation of the company's potential actor on the domestic and international market, highly competitive, of dermato-cosmetic products. In the alternative, the project will develop the company's traditional partnerships with scientific research institutions, in order to connect Romanian applied research to the requirements of the national and European socio-economic environment.

Installation for the automated control of the reproducibility of collagen gel batches for biomedical and cosmeceutical applications Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0429 2022 - 2024

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INOE 2000 - FILIALA INSTITUTUL DE CERCETARI PENTRU HIDRAULICA SI PNEUMATICA BUCURESTI RA (RO)

Affiliation:

Project website: https://www.sanimed.ro/proiect-remedial_37.html

Abstract:

The project aims to significantly improve the performance of the pilot plant for the production of highly purified fluid, semi-solid and solid collagen forms, which operates in the company S.C. Sanimed International Impex S.R.L., using elements of technological process quality engineering. In concrete terms, the improvement will aim at ensuring the reproducibility of the batches and the traceability of the processing of the material being processed, by developing an automated control system of the technological and operating parameters of the pilot plant. Reproducibility will be improved by replacing the manual control with the automated one, and the traceability of the operation will be implemented by sampling in real time and storing in integrum and ad tempus indefinitum the numerical data provided by the sensors which will be added to the installation, as well as their subsequent processing.

The overall objective of the REMEDIAL project is to (i) bring the pilot plant to the functional parameters required by the GMP (Good Manufacturing Practices) provisions in the field of production of biomaterials and medical devices of IIb and III classes, (ii) to prepare the plant for production certification, according to European regulations for the CE mark and (iii) increase the productivity of the installation, by eliminating unproductive times, repeated processing and fraction of tissue debris and residues resulting from incomplete processing of the raw material (horse or cattle tendons).

The project will ensure the transfer of know-how and constructive-applicative solutions from the National Institute of Hydraulics and Pneumatics Bucharest, to the Sanimed company. The object of the transfer is the concrete realization of the system for the control and automation of the operation of the pilot installation for obtaining the highly purified collagen forms, in operation in the productive spaces of the company.

Innovative medical device for emergency and operational medicine Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3396 2020 - 2022

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE MEDICO-MILITARA „CANTACUZINO” (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://www.incdtp.ro/cellmatrix.html

Abstract:

Wound healing is a multiphase and multifactorial physiological process. The complexity of this phenomenon makes the healing process very difficult and painful due to several abnormalities. As a response to this problematic issue, as primary or secondary dressing, a complex composite matrix for hemostasis and connective tissue regeneration will be design, developed and validated. The demonstrative model will consist in three layers, namely semi-adherent or a non-adherent layer, absorptive layer and bacterial barrier layer. For the first layer, different textile structures based on conventional and non-conventional technology will be developed. The textile structures will be made from synthetic, artificial and/or bioresorbable polymers (PGA, PLA) and will be design so that to ensure a pore diameter of 50 µm, considering as being enough to permit the free passage of exudates into the secondary absorbent layer but too small to allow the ingress of granulation tissue. The perforated structure prevents the dressing from adhering to the surface of the wound while the holes allow the passage of exudates to the absorbent layer. The second layer will comprise an absorbent material for absorbing exudates, blood, moisture and other fluid materials from the inner layer and maintains the wound in moist environment. A collagen or collagen cellulosic matrix containing a super-absorbent, e.g., carboxymethyl cellulose/ sodium polyacrylate etc., by electrospinning technologies deposition will be used for absorbent layer in the composite dressing. The third or outer layer comprises a bacterium-impermeable and air-permeable cover film. The cover film also consists of a layer of pressure-sensitive adhesive in its peripheral. The bacterial barrier layer will comprise a flexible, waterproof and breathable material (e.g. polyurethane film of approximately 0.5–1.5 mm thickness, polypropylene or polyethylene such as a low-density, opaque polyethylene film).

CREȘTEREA CAPACITĂȚII DE TRANSFER TEHNOLOGIC și DE CUNOȘTINȚE A INCDTIM CLUJ ÎN DOMENIUL BIOECONOMIEI Call name: Parteneriat pentru transfer de cunostinte (Apel reconstituit pentru pastrarea pistei de Audit - Anul 2015)
105533 2016 - 2021

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE (RO); TEODENT SRL (RO); INSPRESSO SRL (RO); EVOLO CPV S.R.L. (RO); FARMEC SA (RO); I.C.P.E. BISTRITA SA (RO); TERACRYSTAL SRL (RO); PARAPHARM SRL (RO); ETERA PROD S.R.L. (RO); SANIMED INTERNATIONAL IMPEX SRL (RO); AGRO COSM FAN SRL (RO); S.C. ROSEAL S.A. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX SRL (RO)

Project website:

Abstract:

New textiles for parietal defects Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-ERANET MANUNET III-PariTex 2019 - 2021

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://www.paritex.ro

Abstract:

The role of medical devices is essential to the healthcare of citizens. The diversity and innovativeness of this sector contributes significantly to enhancing the safety, quality and efficacy of healthcare in the EU. The challenges related to R&D, emerging technologies and the green economy, as well as issues related to the EU’s trade and regulatory cooperation globally have became more intensive in recent years. SMEs in particular face challenges in this regard. The medical devices sector faces many challenges at national, European and international level, which may have an impact on their innovation capacity and overall competitiveness: Public Health Systems, Finding the balance between patient’s needs and financial sustainability, Competitiveness and innovation. The medical devices with high added value made from resorbable and nonresorbable biopolimers, processed by modern technology (knitting and electrospinning) with linear and spatial structure, functionalized with active agents will be obtained in PariTex project will be a contribution of R&D activity to give an answer for sustainable medical textile device sector. The PariTex project will develop new textiles materials for healing of the parietal abdominal defects, based fibers/ yarns made of nonabsorbable and resorbable polymers (biopolymers) obtained by classical and unconventional (electrospinning) technologies. Knitted and nonwoven fabrics characterized by mass, thickness, porosity,density, dimensions etc. are functionalized by incorporating or coating with substances that have the goal of: reducing adherence to human tissue, reducing the risk of infection, monitoring healing time by using controlled release systems based on natural polymers, reducing abdominal discomfort and associated pain. Will be assessed the level of biological performance, by the test of the mutagenic potential by using the micronucleus test on the hematogenic marrow of mice to determine the sensitizing potential, acute local tolerance, cytotoxicity and subacute toxicity.

The project will contribute to the initiation and consolidation of a value chain for the realization of functional textile structures based on partners' competencies, but also by attracting clusters of textiles and medicine for the application of the results.

Framework technologies for achieving, developing and validating the sterilization of collagen products Call name:
POC-A1-A1.2.3-G-2015/SMIS 107514 2018 - 2020

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA " HORIA HULUBEI " - IFIN - HH

Project partners: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA " HORIA HULUBEI " - IFIN - HH (); SANIMED INTERNATIONAL IMPEX S.R.L. ()

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. ()

Project website:

Abstract:

Conceptual modelling and development of an integrated wastewater system adapted to porous collagen substrates production technologies within SC Sanimed International Impex SRL Call name:
Subsidiary Contract 5831/2018, P40_300/105581, POC A1.-A1.2.3.-G 2018 - 2020

Role in this project: Key expert

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU ECOLOGIE INDUSTRIALA - ECOIND (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: https://partenerecoind.incdecoind.ro/activitatile-proiectului/

Abstract:

Prezentul proiect își propune dezvoltarea, realizarea și testarea unui flux de epurare inovativ pentru apele uzate generate de producția substraturilor colagenice poroase în condiții de funcționare similare celor reale (TRL6). În cadrul proiectului se vor desfășura activități de cercetare industrială și dezvoltare experimentală realizate în parteneriat, care vor conduce la realizarea unui flux tehnologic de epurare bazat atat procese fizico-chimice cât și biologice și adaptat nevoilor specifice ale fluxului productiv al SANIMED. Prin implementarea sa proiectul va contribui efectiv la progresul cunoașterii în tratarea apelor uzate rezultate de la fabricarea substraturilor colagenice poroase, precum și la transferul de cunoștințe de specialitate de la Organizația de Cercetare către membrii echipei de proiect SANIMED.

New technologies and products for health/Framework technologies for the development of biomedical products based on bacterial nanocellulose structures Call name:
POC-A1-A1.2.3-G-2015 2017 - 2019

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI

Project partners: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (); SANIMED INTERNATIONAL IMPEX S.R.L. ()

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. ()

Project website:

Abstract:

Composite hydrogels based on inorganic nanoparticles and collagen with prolonged antimicrobial activity for the prevention of wound infections Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2016-0177 2016 - 2018

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); UNIVERSITATEA BUCURESTI (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL DE VIRUSOLOGIE "STEFAN S.NICOLAU" (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://nanocolagel.sanimed.ro/

Abstract:

Chronic wounds represent a good niche for biofilm development because the impaired immune response promotes infection susceptibility whilst necrotic tissue and debris favor bacterial attachment. Collagen hydrogels represent one of the most efficient treatments in case of both chronic and acute wounds due to their ability to maintain optimal humidity and aeration parameters. Currently, at a national level there is no production of collagen hydrogels aimed for the treatment of chronic wounds, hence these types of products are being imported. In this context, the present project proposal aims to design and obtain new types of multifunctional collagen hydrogels harboring antimicrobial properties in order to favor the healing process of chronic wounds. As a novelty element in comparison to products currently available on the international market, we will design and produce collagen hydrogels containing nanoparticles. Thus, Sanimed International Impex S.R.L will develop a simple and rapid technology to obtain hydrogels functionalized with metalic and oxidic nanoparticles (collagen hydrogels with Ag nanoparticles, collagen hydrogels with ZnO hydrogels and collagen hydrogels with SiO2@ZnO nanoparticles). The novel hydrogels will be tested for their antimicrobial and antibiofilm properties using in vitro and in vivo methods and also for the host response after hydrogel treatment on wounded cells and in vivo lesion murine models, for achieving market preparation.

Technology and equipment for producing collagen-based nanofibrillary structures for resorbable wound dressings Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2016-0174 2016 - 2018

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://nano-ecol.sanimed.ro

Abstract:

The nano-ECol project proposal aims to develop an innovative technology and to implement a demonstrative prototype at the Technology Readiness Level TRL5, for the production of micro- and nano-fibrillar substrata usable as absorbable dressings for wounds and burns. The micro- and nano-fibers will be obtained by electrospinning, starting from colloidal solutions of atelocollagen currently manufactured at S.C. Sanimed International Impex S.R.L. In this respect, the project aims at shifting/promoting the INFIM SPIN 1.0 prototype, developed through a previous project by the National Institute of Materials Physics (INCDFM), and preliminary tested for its atelocollagen electrospinning capacity, from the TRL4 to the TRL5.

The main technological challenges faced by the nano-Ecol project are: (i) preserving atelocollagen macromolecule in a quasi-native state, (ii) providing the products reproducibility, (iii) producing substrates with an area of tens of square dm and thickness of 3 ... 12 mm, (iv) providing a prototype able to work at micropilot scale, with at demand-formulated electrospun compositions, (v) providing rapid structural and dimensional prototyping, (vi) scaling-up the prototype and related technology to industrial level.

The project will benefit from the facilities and logistics of five research centers, of which two belong to Sanimed, and three to INCDFM. Services and facilities provided by all mentioned centers are detailed on the ERRIS platform.

The Sanimed co-funding represents 67.63% of the sum allocated to the company from the public budget, i.e. 25.27% of total buget, and 39.04% of the total payroll.

The expected outcomes of the project meet the Sanimed interest in expanding the range of products and addressability, by manufacturing resorbable dressings with tailored shape, structure and density, obtained from compositions formulated at physician’s request, in order to satisfy specific pacient needs.

Contributions to enhancing the Sanimed SRL’s competitiveness by the knowledge assimilation and potential production implementation of some 3D collagen-polymer hybrid matrices intended to tissue repair Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0397 2016 - 2018

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://www.unibuc.ro/prof/micut_m/

Abstract:

The project proposal mainly aims at knowledge transfer to economic operator regarding the obtaining and development of 3D collagen-polymer hybrid biomaterials intended to biomedical applications. The practical implementation of the proposal should lead to enhancing competitiveness of private economic entity in order to develop itself in the near and middle-term future. In line with economic partner, the public entities University of Bucharest and ICECHIM (project partners) have identified aspects of scientific and technological existing at private partner, the weaknesses and strengths of these aspects, as a useful basis for designing new collagen-based hybrid biomaterials. In addition, the purpose that such kind of biomaterials be used in the process of tissue repair requires accounting a number of key characteristics against which it is possible to design, realize and develop this kind of hybrid collagen-polymer system: biocompatibility, bioresorbability, mechanical properties, internal and external morphology and manufacturing technology.

Analytical methods for characterization of oligo/polypeptides and polysccharides applied in cosmetics and foods: proposal, development and validation Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0175 2016 - 2018

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI

Project partners: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://www.ch.tuiasi.ro/cercetare/proiecte/AnaMet/default.html

Abstract:

This project aims to contribute to knowledge development in the area of physicochemical characterization methods applied to oligo/peptide and/or polysaccharide systems using the modern equipment recently acquired by SANIMED International Impex SRL company and the extensive expertise of two research teams: one from the Faculty of Chemical Engineering and Environmental Protection, „Gheorghe Asachi” Technical University of Iasi and the second one from the „Petru Poni” Institute of Macromolecular Chemistry from Iasi. Highly skilled professors, researchers and specialists from both institutions will be actively involved in designing experiments, analyzing, testing and validation of SANIMED equipment and technology in order to help them adapt to the new trends by developing innovative products and processes. Special emphasis will be placed on establishing structure - properties correlations. Knowledge transfer will create premises for the development and optimization of technologies involved in the industry of cosmetics and nutritional products.

The main directions of interest are: (i) Transfer of knowledge regarding the properties of oligo / polypeptides, and polysaccharides; (ii) Studies regarding the correlation between structure of raw materials and the properties of the final products using modern analysis methods (chromatography, spectroscopy, microscopy, rheology) and SANIMED equipment; (iii) Studies on the physicochemical properties of the considered materials, using high performance equipment, present at the research units, to identify the needs of the economic agent; (iv) Studies to assess the influence of the nature of the analyzed compounds on the texture and sensory properties of the final products; (v) The use of modern methods of study in the morphological analysis of formulated products; (vi) Optimization of the formulation step and application of design of experiments; (vii) Interconnection of information in terms of chemistry, physics and informatics.

Technology optimization and training in advanced purification processes of collagen for pharmaceutical and biomedical applications, at S.C. Sanimed International Impex S.R.L. Call name: P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0180 2016 - 2018

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI

Project partners: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://www.ak-pur.tuiasi.ro

Abstract:

The “aK-Pur” project is dealing with knowledge transfer in advanced purification of colloidal solutions of atelocollagen for pharmaceutical and bio-medical applications, in order to optimize the current technology applied to S.C. Sanimed International Impex S.R.L., and to improve the skills of personnel involved in the manufacturing of collagen porous substrates for the class III sterile medical devices, at the aforementioned company. The transfer consists in: (i) the assessment of current technology, (ii) technology redesign, and (iii) changing the purification step through the replacement of the dialysis operation by tangential flow diafiltration through porous cartridges. In addition, new manufacturing regulations, and a system of training of personnel involved in the whole technological flow will be developed.

The project will benefit from the facilities and logistics of three research centers from the "Gheorghe Asachi" Technical University of Iasi, as well as from those of the "Research infrastructure for collagen products” and the “Research centre and innovative services in advanced biotechnologies", currently in place at Sanimed company. Services and facilities provided by all five mentioned centers are detailed on the ERRIS platform.

The project team includes four members of the faculty staff as senior researchers, and two master students, who will improve their practical training. The total value of the anticipated expenditure of the project is of 450,000 lei, of which 49% staff costs, 30% for materials and reagents, 5% third-party services, 4% to mobilities, and 12% overheads.

Expected effects after project completion meet the company's demands for increased process yields and product quality, but also for human resource with improved skills and competencies in collagen processing.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects