BrainMap

Mariana Marin

- INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Researcher | Scientific reviewer

Curriculum Vitae (05/05/2025)

Expertise & keywords

Electrochemical platforms based on nanocomposite materials for the detection of biologically active compounds Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-3693 2022 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI

Project partners: UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Affiliation:

Project website: https://www.icf.ro/pr_2022/MATSENSBIO/MATSENSBIO.html

Abstract:

The project MATSENSBIO is aiming to develop sensitive and selective electrochemical sensing platforms based on nanocomposites materials for the analysis of relevant biologically active compounds like neurotransmitters and antioxidants. The monitoring of neurotransmitters and antioxidants is of paramount importance in the early diagnosis and the management of various diseases. Therefore, the main objective of the project is aiming to address these societal needs related to the development of electrochemical sensors for health monitoring. The electrochemical sensors are developed by the modification of conventional electrode substrates, glassy carbon, screen printed and metal electrodes (Pt, Au) with nanocomposites materials consisting of conducting polymers (CP) and metal/inorganic nanoparticles (MeNPs). The CPs-MeNPs materials combine two or more characteristic properties featured by the components, namely good electrochemical stability, favorable immobilization matrix and microenvironment brought by the CPs like poly(3,4-ethylenedioxythiophene), poly(3,4-ethylenedioxypyrrole), with high electrocatalytic activity of MeNPs (Au, Pt, Ag) and inorganic ones like Prussian blue. The CPs-MeNPs materials will be prepared via in situ electrodeposition onto electrode substrates by using innovative procedures based on sinusoidal currents and voltages. The electrochemical sensors will be tested and validated in laboratory environment toward the detection of benchmark neurotransmitters, epinephrine and serotonin, and relevant antioxidants, lipoic acid and quercetin. The CPs-MeNPs materials preparation procedures (methods) and the electrochemical sensors (products) are the main outcomes of the project. The use of commercially available electrode substrates (GC, Pt, Au, ITO), including SPEs for single-use sensors, is intended to provide the basic supports upon which the nanocomposite materials will be deposited to develop the envisaged products – the electrochemical sensors.

(Poly)saccharides-derived hydrothermal carbonaceous materials–a platform for developing a new generation of copper-based green electrochemical sensors Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-2324 2021 - 2023

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Project partners: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Affiliation:

Project website: http://www.icf.ro/pr_2020/GREENSENS.pptx

Abstract:

(Poly)saccharides represent ideal natural sources for the eco-friendly hydrothermal synthesis of semi-carbonized materials (hydrothermal carbons, HCs). HCs are nowadays considered alternative green conductive materials to more expensive graphene or carbon nanotubes (CNTs). The main objective of the proposal is the development of a new generation of sustainable electrochemical sensors constructed from Cu-based/(poly)saccharide-derived HCs composites. The engineering of HCs supports through hard/soft template strategies or the obtaining of HCs/CNTs hybrid structures gave rise to stable mesoporous materials with controlled pore structures that are expected to enhance the conductivity of the carbonaceous materials. The embedding of Cu-based nanoparticles into the HCs matrix or supported on the pre-designed porous HCs materials will lead to composites of which sensitivity toward several analytes will be tested. The social and environmental impact, relying on our scientific results, represent a step forward to a cleaner environment. The involvement of young researchers in our team will help them to acquire knowledge and new research skills and will also familiarize them with research themes related to green chemistry issues, like the minimization of waste and clean synthesis.

COMPLEX VALORISATION OF BLACK SEA REGION BIORESOURCES BY DEVELOPING AND APPLYING INNOVATIVE AND EMERGING BIOTECHNOLOGIES Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0701 2018 - 2021

Role in this project:

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners: UNIVERSITATEA OVIDIUS (RO); INSTITUTUL NAŢIONAL DE CERCETARE-DEZVOLTARE MARINĂ "GRIGORE ANTIPA"-I.N.C.D.M. CONSTANŢA (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); STATIUNEA DE CERCETARE DEZVOLTARE PENTRU VITICULTURA SI VINIFICATIE MURFATLAR (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: https://univovidius.wixsite.com/inobiomar

Abstract:

Natural products from marine species are increasingly studied as their functional properties are discovered. These properties have benefits for human health while depending on their geographical region of origin. As abundant marine resources with insufficiently exploited therapeutic potential exist, the present proposal aims to harness the Black Sea bioresources through developing innovative technologies for obtaining biorenewable pharmaceutics preparations. The membrane/bioadhesive disks preparations consist of bioactive compounds from marine extracts encapsulated into mesoporous functionalized silica matrices and have controlled release. The Black Sea bioresources valorization will be improved by using the residual biomass from technological flux as biofertilizer for vineyards. New technologies for efficient extraction and preservation of active ingredients, encapsulation in pharmaceutical and nanostructured silica matrices, obtaining modern, therapeutically/cosmetic efficient formulations tested in vitro, will be developed. The project will be completed by a multidisciplinary consortium composed of UOC, INCDM, UPB, INCDSB, having a new research center with personnel deficit (Romanian Academy-ICF) and a relaunching center- SCDVV Murtfatlar, which will develop and use the common infrastructure, existing and newly created human resources, both through the project implementation and future collaborations, while strengthening the partners’ institutional capacity through improving their services offers. The project will achieve TRL 5. The main goal of the complex project can be achieved through the complementarity of the 5 component projects, having 6 patent applications and developing new fabrication technologies for 3 pharmaceutical formulations with synergetic action as deliverables, which can be translated to economic beneficiaries.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects