BrainMap

Mr. MIHAEL CRISTIN ICHIM

PhD

- INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Researcher | Scientific reviewer

Expertise & keywords

Mobilitate cercetător MIHAEL CRISTIN ICHIM Call name: P 1 - SP 1.1 - Proiecte de mobilitate pentru cercetatori, 2019
PN-III-P1-1.1-MC-2019-0345 2019 - 2019

Role in this project:

Coordinating institution: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT

Project partners: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Affiliation: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Project website:

Abstract:

Advanced and emergent technologies to obtain vegetal extracts used in innovator food supplements Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-1604 2017 - 2018

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); CENTRUL DE CERCETARE SI PRELUCRARE A PLANTELOR MEDICINALE PLANTAVOREL SA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Project website: http://tevisped.webs.com

Abstract:

This proposal, having as an aim to obtain innovator formulas of food supplements with an action to sustain the hepatic function, will capitalize two autochthonous medicinal species (Scirpoides holoschoenus and Helichrysum arenarium), the first used in traditional medicine, the second in modern medicine (in some European countries, highlighted by EMA). For the first species, we aim the experimental field cultivation to preserve the biodiversity and to assure the vegetal raw material, by multiplication techniques and the establishing of technological parameters. The plants from culture and wild flora will be phytochemically evaluated. Both vegetal species will be capitalized in an innovator mood so that there will be achieved comparative studies for extraction using classical (static and dynamic) and non-conventional (SPE, ultrasounds, supercritical fluids etc.) methods. The best method will be selected. The extracts will be phytochemically characterized (TLC, HPTLC, densitometry, HPLC, GC-MS, UV/VIS spectrophotometry, etc.), and tested biologically (to demonstrate the action of sustaining the hepatic function) and phytobiologically (cytogenicity, cytotoxicity). The compounds with the action of sustaining hepatic function, are easily to be assimilated and non-toxic and contribute to the good functioning of the organism. Finally, an extraction technique will be elaborated (laboratory stage), for obtaining selective plant extracts with a rich content in bioactive compounds of interest and some original bio-complexes of plant extracts will be obtained as vectors for new food supplements. Innovator conditioning formulas (encapsulation) will be realized (laboratory stage), based on plant extracts obtained in experimental test conditions, establishing testing methods for qualitative and quantitative evaluation. This form of conditioning has the advantage of a good and easy administration of the dose pre-established by bio-components, with the protecting of the phytocomplex.

Assessing and monitoring the impacts of genetically modified plants on agro-ecosystems Call name:
199EU 2012 - 2015

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Project website:

Abstract:

Assessing and monitoring the impacts of genetically modified plants on agro-ecosystems Call name:
289706 2011 - 2015

Role in this project: Partner team leader

Coordinating institution: National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA)

Project partners: National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA) (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Project website: http://www.amiga.enea.it

Abstract:

EEA Mobility Grant - MIHAEL CRISTIN ICHIM Call name: EEA - Proiecte de Mobilităţi
EEA-MG-RO-NO-2018-0023 2018 -

Role in this project:

Coordinating institution: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE "STEJARUL" PIATRA NEAMT

Project partners: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE "STEJARUL" PIATRA NEAMT (RO); GenØk – Centre for Biosafety (NO)

Affiliation: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE "STEJARUL" PIATRA NEAMT (RO)

Project website:

Abstract:

project title Call name: P 1 - SP 1.1 - Proiecte de mobilitate pentru cercetatori
PN-III-P1-1.1-MC-2017-1398 2017 -

Role in this project:

Coordinating institution: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT

Project partners: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Affiliation: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Project website:

Abstract:

INTERNATIONAL CONFERENCE ON FOODOMICS - 5th EDITION, Foodomics 2018 - from Data to Knowledge (ICF2018) Call name: P 1 - SP 1.1 - Proiecte de mobilitate pentru cercetatori
PN-III-P1-1.1-MC-2017-1304 2017 -

Role in this project:

Coordinating institution: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT

Project partners: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Affiliation: INCDSB BUCURESTI SUCURSALA CENTRUL DE CERCETARI BIOLOGICE '' STEJARUL'' PIATRA NEAMT (RO)

Project website:

Abstract:

Molecular authentication of complex herbal food supplements for safety and efficacy Call name: EEA Research Programme under EEA Financial Mechanism 2009-2014
EEA-JRP-RO-NO-2013-1-0326 2013 -

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); University of Oslo, The Natural History Museum (NO); UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO); CENTRUL DE CERCETARE SI PRELUCRARE A PLANTELOR MEDICINALE PLANTAVOREL SA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Project website:

Abstract:

The PhytoAuthent project adheres to the health and food theme of the EEA call and addresses current ambiguity in the herbal dietary supplements market in Romania. The project uses a complex and integrative multidisciplinary approach to covering all aspects from legal framework, manufacturing process, suppliers, and consumers to safety issues and authentication. The European Economic Area (EEA) lacks a central public institution to test the composition of herbal products and to verify ingredient claims included on the label. In the USA, consumerlab.org performs independent tests on commercially available dietary supplements and makes its findings available for an administrative fee. Scientific literature has reported several cases of adulteration and counterfeiting of such products, and the results of most studies imply that substitution occurs widely. This raises serious concerns on ethics, safety and efficacy. In addition, unrestricted sale and access and the lack of medical oversight to dietary supplements hampers quality monitoring. Romania is both a major consumer and exporter of raw materials and processed supplements, and it is therefore extremely important to make a comprehensive and critical evaluation of its herbal dietary supplements industry in order to identify its vulnerabilities and to develop models for improved regulation. The European Union directives on food safety and takes into consideration consumer rights to make informed choices about the products they use, and fair and accurate labelling of products is an essential part of that. This project involves local SME herbal producers with the aim of taking a participatory and integrated approach to gain understanding of the challenges and manufacturing process of quality dietary supplements. Different product authentication methods exists, and this project will research, screen and evaluate the accuracy, reliability, effort and cost of these methods for 5 selected medicinal plant cases. The focus will be on new and innovative methods using chemical analysis, DNA barcoding and metabarcoding using next generation sequencing. The project is based on herbal industry knowledge needs, as aims to yield higher quality standards at equal production costs.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects