BrainMap

Georgeta Voicu

- DELTAROM SRL

Researcher

Expertise & keywords

SYNERGICSTIC ACTIVES SYSTEMS FOR REGENERATIVE COSMETICS Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0303 2022 - 2024

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation:

Project website: https://www.sanimed.ro/proiect-grace_36.html

Abstract:

The GRACE project aims to obtain and characterize a range of integrative products, designed to regenerate the epidermis affected by superficial lesions, solar radiation, radiation therapy, or bedsores, using specifically functionalized hydrogels with complexes of inclusion of active ingredients in host molecules. These supramolecular complexes will represent the innovative component in the formulation of a new range of products with applications in the field of regenerative cosmetics. In concrete terms, the GRACE project aims to obtain a range of 3 products: single-dose hydrogel (for superficial lesions), cream gel (for skin affected by radiation) and cleansing gel (for gentle debris removal and cleaning of superficial lesions). In this sense, the project will stimulate the investment in research - technological development from the beneficiary company, as well as the consolidation of the company's potential actor on the domestic and international market, highly competitive, of dermato-cosmetic products. In the alternative, the project will develop the company's traditional partnerships with scientific research institutions, in order to connect Romanian applied research to the requirements of the national and European socio-economic environment.

Installation for the automated control of the reproducibility of collagen gel batches for biomedical and cosmeceutical applications Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0429 2022 - 2024

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); INOE 2000 - FILIALA INSTITUTUL DE CERCETARI PENTRU HIDRAULICA SI PNEUMATICA BUCURESTI RA (RO)

Affiliation:

Project website: https://www.sanimed.ro/proiect-remedial_37.html

Abstract:

The project aims to significantly improve the performance of the pilot plant for the production of highly purified fluid, semi-solid and solid collagen forms, which operates in the company S.C. Sanimed International Impex S.R.L., using elements of technological process quality engineering. In concrete terms, the improvement will aim at ensuring the reproducibility of the batches and the traceability of the processing of the material being processed, by developing an automated control system of the technological and operating parameters of the pilot plant. Reproducibility will be improved by replacing the manual control with the automated one, and the traceability of the operation will be implemented by sampling in real time and storing in integrum and ad tempus indefinitum the numerical data provided by the sensors which will be added to the installation, as well as their subsequent processing.

The overall objective of the REMEDIAL project is to (i) bring the pilot plant to the functional parameters required by the GMP (Good Manufacturing Practices) provisions in the field of production of biomaterials and medical devices of IIb and III classes, (ii) to prepare the plant for production certification, according to European regulations for the CE mark and (iii) increase the productivity of the installation, by eliminating unproductive times, repeated processing and fraction of tissue debris and residues resulting from incomplete processing of the raw material (horse or cattle tendons).

The project will ensure the transfer of know-how and constructive-applicative solutions from the National Institute of Hydraulics and Pneumatics Bucharest, to the Sanimed company. The object of the transfer is the concrete realization of the system for the control and automation of the operation of the pilot installation for obtaining the highly purified collagen forms, in operation in the productive spaces of the company.

Composite hydrogels based on inorganic nanoparticles and collagen with prolonged antimicrobial activity for the prevention of wound infections Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2016-0177 2016 - 2018

Role in this project:

Coordinating institution: SANIMED INTERNATIONAL IMPEX S.R.L.

Project partners: SANIMED INTERNATIONAL IMPEX S.R.L. (RO); UNIVERSITATEA BUCURESTI (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL DE VIRUSOLOGIE "STEFAN S.NICOLAU" (RO)

Affiliation: SANIMED INTERNATIONAL IMPEX S.R.L. (RO)

Project website: http://nanocolagel.sanimed.ro/

Abstract:

Chronic wounds represent a good niche for biofilm development because the impaired immune response promotes infection susceptibility whilst necrotic tissue and debris favor bacterial attachment. Collagen hydrogels represent one of the most efficient treatments in case of both chronic and acute wounds due to their ability to maintain optimal humidity and aeration parameters. Currently, at a national level there is no production of collagen hydrogels aimed for the treatment of chronic wounds, hence these types of products are being imported. In this context, the present project proposal aims to design and obtain new types of multifunctional collagen hydrogels harboring antimicrobial properties in order to favor the healing process of chronic wounds. As a novelty element in comparison to products currently available on the international market, we will design and produce collagen hydrogels containing nanoparticles. Thus, Sanimed International Impex S.R.L will develop a simple and rapid technology to obtain hydrogels functionalized with metalic and oxidic nanoparticles (collagen hydrogels with Ag nanoparticles, collagen hydrogels with ZnO hydrogels and collagen hydrogels with SiO2@ZnO nanoparticles). The novel hydrogels will be tested for their antimicrobial and antibiofilm properties using in vitro and in vivo methods and also for the host response after hydrogel treatment on wounded cells and in vivo lesion murine models, for achieving market preparation.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects