BrainMap

Mr. Radu Necula

Scientific Researcher (CS)

Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Researcher

Web of Science ResearcherID: K-5039-2012

Expertise & keywords

Development of a functional model for sustainable capitalization of genetic and phytochemical diversity of Arnica montana L. wild populations in the Northern area of the Romanian Eastern Carpathians Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0791 2014 - 2017

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI (RO); UNIVERSITATEA "ŞTEFAN CEL MARE" DIN SUCEAVA (RO); CENTRUL DE CERCETARE SI PRELUCRARE A PLANTELOR MEDICINALE PLANTAVOREL SA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Project website: http://ccb-stejarul.ro/2014/ARMOREC.html

Abstract:

The ARMOREC project has as the general aim the optimizing the capitalization of the Arnica montana L. natural populations from the north of the Eastern Carpathians by developing a new innovative model for the sustainable production of raw material (collecting, cultivation, conditioning) and of some eco-efficient processing methods of the vegetal material.

In this respect, it is necessary to develop inter- and transdisciplinary studies in the fields of biology, ecology, geomorphology, biotechnology and phytochemistry, grouped in 3 major components: the environment componen with connex aspects, the phytochemical and economical component – the capitalization by the industrial partner (SME).

The members of the concortium, by their expertise and experience in the project domain has the competences necesary to the development of the researches with a high degree of complexity and interdisciplinarity.

To attain the general objective of the project, we will process a series of activities grouped in 5 work packages corresponding the specific objectives:

1. Evaluating the bioproductive potential in the natural populations of A. montana from the north of thr Eastern Carpathians, on the basis of the quantitative and qualitative determinations onthe biomass yield, as well as the content of biologically active principles.

2. Evaluating the preservation status of the A. montana species in the target area, correlated to the main pressure factots.

3. Elaboration of a model of developing a coplimentary source of raw material by conventional and biotechnological methods.

4. The development of some eco-efficient methods of extraction and phytochemical anaysis for the main biologically avtive compounds – sequiterpen-lactons, flavonoids and phenolic acids, essential oil.

5. The development of an experimental model for the sustainable capitalization of A. montana (natural populations and experimenta cultures) by obtaining and characvterizing the specific phytocomplexes with multiple uses.

The originality of the project resides both in selecting the study and analysis methods and in the holistic approach of the problem that aim the whole capiatlizing chain of the principles of sustainable growth. It is the first time when an interdisciplinary approached is proposed to model the effect of the abiotic fators on the distribution of A.montana on the basis of a spacial analysis model.

Reaching the aims will promote the sustainable capitalization of the species in the north of the Eastern Carpathians, that will have complex , interdisciplinary stadie at the basis (with economic and scientific importance) and will generate added value over the whole chain of capitalization and will also assure the biodiversity conservation.

Although for A. montana he interst kept itsel at a high international level, in România, the species is slightly capitalized, both economically and scientifically. Thus, thorough studies are scrace, integrated in the present state of the species in the natural populations, in the preservation and capitalizing and promoting of autochthonous products. The majority of the studies achieved in Romania refer to the Apuseni Mountains, in the Eastern Carpathians, the species being only mentioned in some floristic studies.

By developing this project, we aim the sustainable capitalization of the species at local and regional level, in relation to the peculiarities of the species, and of its status as a rare and vulnerable species and the demands of the market.

Approaching a species that has already for long been studied worldwide, represents a reason to elaborate a capitalization plan of the species, this being in the same time a very good model to capitalize other medicinal, aromatic and food species of the mountain zone. In the time, this model of sustainable capitalization may be adapted and extrapolated to all the Romanian areals of this species.

Izolarea unor fitocomplecsi cu actiune antioxidanta utilizabili in integratori alimentari Call name: Cecuri de Inovare - 2012
PN-II-IN-CI-2012-1-0278 2012 - 2013

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt

Project partners: S.C. Centrul de Cercetare si Prelucrare Plante Medicinale "Plantavorel" S.A. (RO); Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt (RO)

Affiliation: Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt (RO)

Project website:

Abstract:

Proiectul porneste din necesitatea sustinerii calitatii vietii prin aport suplimentar de nutrienti antioxidanti, benefici pentru organismului uman in contracararea efectelor nocive induse de factori intrinseci si extrinseci.

Obiectiv general: cresterea calitatii produselor de tip supliment alimentar inovativ, utilizarea unor metode avansate de elaborare si control prin valorificarea eficienta a cunostintelor partenerilor.

Obiective specifice: cresterea gradului de inovare in domeniul suplimentelor alimentare de tip integrator alimentar, pe baza studiului avansat asupra activitatii antioxidante a unor fitocomplecsi izolati din specii vegetale mai putin valorificate; imbunatatirea gamei de produse cu actiune antioxidanta cu integratori alimentari destinati imbunatatirii calitatii vietii; elaborarea de integratori alimentari destinati edificarii unei sanatati de durata.

Necesitatea proiectului deriva din cerinta actuala de largire a gamei de produse antioxidante cu adresabilitate asupra unui grup tinta (in special persoane de varsta a 3-a).

Serviciile furnizate constau in realizarea urmatoarelor activitati: selectia de produse vegetale (PMA mai putin valorificate) cu actiune antioxidanta marcanta si investigarea potenatialului biosintetic pentru compusii antioxidanti (compusi polifenolici, terpenici, fitosterolici) prin CSS, spectroscopie, HPLC, GC-MS; evaluarea actiunii antioxidante prin metode moderne comparative si selectia fitocomplexului pentru introducerea in formule; determinarea potentialului antioxidant a fitocomplexului prin metode de tip DPPH, TROLOX, Vit. C; obtinerea unor tipuri de extracte vegetale prin modelarea parametrilor extractivi (solvent, timp, temperatura) si a tehnicilor de extractie; elaborarea si caracterizarea de formule prin asocierea fitocomplexului/principiului activ selectat din extractele vegetale elaborate;

Produsele includ forme noi pentru infuzie/decoct si extracte vegetale fluide, respectiv imbunatatirea unei formule preexistente.

Transfer tehnologic si asistenta pentru implementarea tehnologiei de micropropagare la bioforme selectate de lavanda (Lavandula ssp.). Call name: Cecuri de Inovare - 2012
PN-II-IN-CI-2012-1-0251 2012 - 2013

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt

Project partners: SC SNAILBOX SRL (RO); Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt (RO)

Affiliation: Institutul National de Cercetare – Dezvoltare pentru Stiinte Biologice Bucuresti / Centrul de Cercetari Biologice “Stejarul” Piatra Neamt (RO)

Project website:

Abstract:

Proiectul are ca obiectiv general infiintarea unei pepiniere pentru specii de plante medicinale si aromatice (Lavandula angustifolia si Lavandula hybrida), prin tehnologia de multiplicare in vitro, pentru propagarea unor bioforme cu bioproductivitate ridicata (biomasa si principii active), adaptate conditiilor pedo-climatice din Romania.

Obiective specifice:

- selectia bioformelor, caracterizarea fitochimica a acestora

- transferul tehnologiei de micropropagare

- infiintarea unui laborator de culturi de tesuturi

- instruirea personalului

- realizarea lotului initial

Serviciul consta in transferul tehnologiei de multiplicare prin culturi de tesuturi si furnizarea unui numar de plante (100-150 indivizi) pentru infiintarea lotului initial. Totodata, se parcurg etapele infiintarii laboratorului propriu pentru preluarea tehnologiei de multiplicare la beneficiar, precum si instruirea personalului in vederea insusirii tehnicilor de lucru.

Plantele-donor vor fi caracterizate din punct de vedere fitochimic, pentru evidentierea continutului de ulei volatil – analiza prin gaz-cromatografie cuplata cu spectroscopie de masa (GC-MS) si a continutului in polifenoli – cromatografie de lichide de inalta performanta (HPLC).

Evaluarea fitochimica vizeaza caracterizarea materialului vegetal (bioforme) care va fi multiplicat in vitro, pentru realizarea unor colectii cu insusiri morfo-fitochimice bine definite.

Oportunitatea proiectului rezulta din cerintele pietii pentru materia prima vegetala de Lavandula ssp., care implica dezvoltarea de culturi standardizate, pentru care cererea de material saditor este semnificativa. Importanta sa economica rezida din continutul in principii active de tip antioxidant (polifenoli) si in mod special al uleiului volatil, cu aplicabilitate in scop alimentar, cosmetic si fitoterapeutic.

Infiintarea pepinierei se justifica prin necesitatea existentei unor furnizori certificati de material saditor pe piata romaneasca, cu caracteristici defini

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects