BrainMap

Mr. Sergiu Coseri

Dr.

Head of Department, Senior Researcher - INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Researcher

Dr. Sergiu Coseri is head of the "Polyaddition and Photochemistry" department at „Petru Poni” Institute of Macromolecular Chemistry Iasi. He received his Ph.D. in organic chemistry in 2001 from the Romanian Academy and Technical University Iasi. He then continued as a postdoctoral fellow at Queens University in Kingston, Ontario, Canada for one year, and then, for another two years, between 2003-2005 he was a Visiting Fellow at Canadian Government Laboratories, NSERC (Natural Sciences and Engineering Research Council of Canada), at National Research Council Ottawa, Canada, under the supervision of Keith U. Ingold, in the field of kinetic and reaction mechanisms involving nitroxyl free radicals. After receiving a NATO reintegration grant, in 2005, he moved back to the „Petru Poni” Institute of Macromolecular Chemistry Iasi, starting his research group in the chemical functionalization of polysaccharides, under mild and environmentally friendly conditions.

Web of Science ResearcherID: http://www.researcherid.com/rid/F-2801-2012

Curriculum Vitae (19/01/2026)

Expertise & keywords

Nanocellulosic hybrid Janus aerogels with high floatability for synchronous photocatalytic dyes mineralization and hydrogen production Call name: P 5.1 - Proiecte de Cercetare Exploratorie - Competiția 2023
PN-IV-P1-PCE-2023-1020 2025 - 2027

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation:

Project website: https://icmpp.ro/projects/l2/about.php?id=184

Abstract:

Environmental protection has risen to the top of global agenda, two of the most pressing issues to be faced by the world are water contamination and energy crisis. Photocatalysis, a green technology, is one of the most promising pathways to relieve these problems, being intensely used in pollutants degradation and H2 production, a clean energy source. Despite recent progress in designing highly active photocatalysts, there are several limitations (catalyst reusability, inefficient solar energy and mass transfer, s.o.) that impede their practical large-scale applications. In the current project, these challenges are tackled by designing a floatable photocatalytic platform with metal-doped ZnO NPs constructed from nanocellulosic hybrid aerogels with Janus structure achieved by hybridization of nanocellulose fibers (CNFs) with a single molecular unit, vinyltrimethoxysilane. When siloxane groups are exposed on the CNFs surface, hydrophilic aerogel will be formed; conversely, when carbon atoms are exposed on the CNFs surface, hydrophobic aerogel will be formed. The porous assembly with Janus structure with hydrophilic layer (downer) and hydrophobic one containing photocatalys ZnO NPs (upper) is designed to optimize the ability of the nanocoposite to float and to ensure efficient light delivery while preserving a facile water and pollutants supply. The photocatalytic performance will be evaluated in the simultaneous processes of hydrogen generation and organic pollutants removal.

Triple-Decker Hydrogel Powered by Multi Dynamic Networks Endowed with Motion Sensing Abilities Call name: P 5.1 - Proiecte de Cercetare Exploratorie - Competiția 2023
PN-IV-P1-PCE-2023-0558 2025 - 2027

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Project website: https://icmpp.ro/projects/l2/about.php?id=185

Abstract:

Ionic conductive hydrogels made from naturally available materials, are the best options for creating flexible electronics. However, cellulosic hydrogels featuring both high mechanical strength and ionic conductivity remain extremely challenging to achieve because the ionic charge carriers tend to destroy the hydrogen-bonding network among cellulose. In this project, we propose a supramolecular engineering strategy to boost the mechanical performance and ionic conductivity of cellulosic hydrogels. In this approach, triple polymeric networks design mimicking a sandwich structure are used to construct the ionic conductive elastomer. In a brand-new, system of deep eutectic solvents (DESs) employed as a reaction medium, the three polymers—polyvinyl alcohol, nanofibrillated cellulose dialdehyde, and a polyamine made from polyacrylonitrile—are mixed and allow forging an impressive structure with nanofibrillated cellulose strongly caught between the other two polymers. The proposed DES, combines choline chloride with 4-carboxyphenylboronic acid, ensuring the simultaneous fulfillment of at least three requirements—homogeneous reaction media, supplier of ester boron bonds, and ionic conductivity—in a straightforward yet clever manner. In the proposed working plan is realized, we anticipate that the exceptional mechanical qualities, self-healing, and electrical conductivity of hydrogels will have several potential applications in the fields of intelligent robots, and human care.

Mobilitate cercetător cu experiență din diaspora Valentin Nica Call name: PNCDI IV, P 5.2 - SP 5.2.2 - Proiecte de mobilitate pentru cercetători cu experiență din diaspora, MCD-2024
PN-IV-P2-2.2-MCD-2024-0432 2024 - 2024

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation:

Project website:

Abstract:

Expanding cellulose’s boundaries towards the fabrication of superior proton conductive membranes for fuel cells Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-0476 2021 - 2023

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation:

Project website: https://icmpp.ro/projects/l2/about.php?id=37

Abstract:

The design of chemically stable proton conductive membranes with high selectivity for application in fuel cells remains a significant challenge. In our project, we propose a new approach to construct proton conductive membranes based on a cheap, abundant, and renewable resource, based on cellulose. Our strategy involves firstly, selective oxidation and functionalization of cellulose, in order to increase its versatility, by introduction high amounts of carboxylic groups, able to serve as active sites of proton conductivity. Besides, nanocellulose prepared from agricultural wastes will act as a redoubtable reinforcing agent as well as providing high proton conductivity. Moreover, this matrix will incorporate different nitrogen-containing heterocycles. These heterocycles are “dry” proton conducting ionomers which can substitute water because they form similar hydrogen bond networks as water. The complex interactions between the polymeric matrix (abundant in the COOH and OH groups) and the low molecular weight heterocyclic dopant, bearing nitrogen atoms and double bonds, create favorable prerequisites to realize new materials with conductive properties. The replacement of water by heterocycles should result in the cellulose based composites characterized by the conductivity in the intermediate temperature range (over 100oC), under anhydrous conditions, desirable for various electrochemical devices, and are relevant in modern material science.

HIGHLY SENSITIVE IMMUNOASSAY DEVICE, BASED ON NATURAL RESOURCES Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-0169 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Project website: https://icmpp.ro/projects/l2/about.php?id=26

Abstract:

In the last years, significant progress has occurred in information technology, sensors, and materials science. In medicine particularly, a timely fashion detection of a certain disease and accurate diagnosis is crucial. From this point of view, point-of-care biosensors is envisioned as a future tool. This research project proposes a new approach to fabricate such highly sensitive biosensors to detect proteins. The strategy involves the activation of cellulose substrate, by a nanostructured engineering procedure to selectively introduce a high amount of carboxyl groups, followed by anchoring specific moieties which will eventually act as a triggering sites for the specific detection and immobilization of proteins. Two proteins were used as a model analyte to fabricate the immunosensor, i.e. human IgG, and bovine serum albumin. The proposed biosensor may exhibit a good specificity, stability, and reproducibility. Our strategy may pave a simple way to fabricate highly sensitive immunosensors for a wide range of applications.

Mimicking living matter mechanisms by five-dimensional chemistry approaches Call name: P 4 - Proiecte Complexe de Cercetare de Frontieră
PN-III-P4-ID-PCCF-2016-0050 2018 - 2022

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL DE BIOLOGIE SI PATOLOGIE CELULARA ,,NICOLAE SIMIONESCU'' (RO); CENTRUL DE CHIMIE ORGANICA AL ACADEMIEI ROMANE "C.D.NENITESCU" (RO)

Affiliation: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Project website: http://www.intelcentru.ro/5D-nanoP/

Abstract:

Mimicking the living matter mechanism of cooperation by complementarity represents one of the most challenging tasks of supramolecular chemistry. For now the solution consists in using particularly designed molecular unimers, endowed with the necessary amount of chemical information.

The 5D-nanoP project is dedicated to interfacing the fundamental research area of constitutional dynamic chemistry with the practical approaches of medicinal chemistry and biomedical applications. In the spirit of a metaphor of Jean-Marie Lehn (Nobel Prize in Chemistry, 1987), the project aims to materialize the concept of 5D chemistry in designing, synthesizing, characterizing, and using molecules with conditional affinity, to build versatile supramolecular nanoplatforms able to vectorize compounds of pharmaceutical or biochemical relevance, and genetic actuators, all of them involved in physiologic and pathologic processes at cell- and tissue-level.

The project will add the layer of 5D chemistry over the backgrounds of molecular assembling line techniques to produce particulate nanoplatforms, self-assemblable in the virtue of the chemical information stored by the designed unimer molecules. Two modern techniques of building dynamic chemical structures will be considered: (i) the use of self-immolative linkers, and (ii) the space stepwise and time phased (microfluidic) assisted synthesis. To prove the applicability of the produced nanoplatforms, an ex vivo cell cultivation system will be developed to emulate tissue/tumor niches.

Eight teams will be involved in the 5D-nanoP project to cover the main addressed research areas: (i) the in silico molecular design, (ii) the development of a unimers chemical library, (iii) the development of a molecular assembling line, (iv) the conjugation of the developed platforms with chemical species of biomedical interest, (v) the build of ex vivo emulating niches, and (vi) the bio-oriented assessment of nanoconstructs efficacy.

Engineering the raw natural products: cellulose-based biointerface for immunoassays Call name: P 4 - Proiecte de Cercetare Exploratorie
PN-III-P4-ID-PCE-2016-0349 2017 - 2019

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Affiliation: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO)

Project website: http://eraw.icmpp.ro

Abstract:

The immobilization of proteins and other biomolecules is an essential technique in several biotechnical applications. Diagnostic applications are rely largely on immobilization of antigens or antibodies using a number of different formats. There is a continuous need to improve and diversify technologies for immobilization for the development of new formats, better economy, and performance. Human immunoglobulin G (hIgG) is the second most abundant protein in human blood, with a concentration of 6.6 to 14.5 mg mL-1 in normal human plasma, being the principal constituent of the immune system. Many autoimmune diseases are related to hIgG and its concentration levels are generally indicative of an individual’s immune status to particular pathogens. Our research focuses on sustainability and aims at contributing solutions for creating new chemicals and materials using renewable sources. Cellulose is a perfect example of a renewable raw material: versatile, abundant, bioabsorbable and biocompatible. Unlike molecules derived from oil, which possess few chemical functional groups, biomass features a diverse selection of functionalities that can be used for the preparation of innovative chemical products. This proposal refers to a new strategy for preparing an efficient biointerface for immobilization of biomolecules on selectively-modified polysaccharide, i.e. oxidized cellulose. To achieve this goal, the initial engineering of the cellulose surface, by introduction of hydrophilic carboxylic groups is designed as an alternative to the less efficient existing protocols. This would provide the means for affordable and stable cellulose-based biointerface for immunoassays. Molecular interactions would be analyzed by using surface-sensitive techniques such as quartz crystal microgravimetry (QCM), surface plasmon resonance (SPR), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and several specific other techniques.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator	Download (25.11 kb) 20/03/2017
List of research grants as partner team leader	Download (17.67 kb) 20/03/2017
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager	Download (23.24 kb) 05/05/2016
R&D activities in enterprises
Peer-review activity for international programs/projects	Download (12.29 kb) 12/04/2024