BrainMap

Toma Fistos

- Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Researcher

Curriculum Vitae (29/07/2020)

Expertise & keywords

Advanced ecological solutions to increase the food safety of vegetables and fruits, from producer to consumer Call name: PNCDI IV, SP 5.7.1 - Proiect de transfer la operatorul economic
PN-IV-P7-7.1-PTE-2024-0607 2025 - 2027

Role in this project:

Coordinating institution: HOFIGAL EXPORT IMPORT SA

Project partners: HOFIGAL EXPORT IMPORT SA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO)

Affiliation:

Project website:

Abstract:

In the context of growing public health and environmental sustainability concerns, research into ecological solutions to improve the food safety of fruits and vegetables is a focal point of contemporary scientific activities. In this regard, the purpose of the project proposal "Advanced ecological solutions for increasing the food safety of vegetables and fruits, from producer to consumer - SIGUR" is the transfer of an innovative technology for obtaining natural surfactants and conditioning them with phytocompounds with high potential for use in order to develop an ecological solution for washing fruits and vegetables with antimicrobial action, to an economic agent with a solid tradition in Romania in the cultivation of medicinal and aromatic plants, their processing, development, implementation of technologies and the production of homeopathic, gemoderivative and galenic phytotherapeutic products. In particular, the project focuses on the transfer of a materialized technology into an ecological solution intended to safely remove dirt, bacteria, pesticides and wax from fresh fruits and vegetables, without altering their taste and properties.

BIO-INSPIRED SYSTEMS BASE ON INTERFERENCE PIGMENTS USED AS EXTENDED UV-LIGHT SHIELDING MATERIALS Call name: PNCDI IV, SP 5.7.1 - Proiect experimental demonstrativ
PN-IV-P7-7.1-PED-2024-0838 2025 - 2027

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); PANAIT INTL SRL (RO)

Affiliation:

Project website:

Abstract:

The theme of the project proposes the synthesis of new hybrid organic-inorganic materials with multiple optical and free radical scavenging properties. These materials will be made by modifying the inorganic-mica matrix, by two methods of reducing the particle size, top-down (grinding, ultrasonic, hydrothermal) and/or by the bottom-up method by modifying the surface following the grafting of hydrophilic/hydrophobic functional groups . Both methods aim to increase the affinity of the host matrix towards the coumarin-derived fluorophore compounds. Obtaining the new hybrid materials aims at the design of multicomponent structures that, through the architecture of the support matrix, are capable of hosting natural or synthetic coumarin compounds with absorption in the 280-500 nm range and fluorescent emission. The resulting hybrid materials will screen light in the intended dimension through cumulative processes of interference, reflection, absorption and fluorescence, thus being able to be used as protective screens against UV light and blue light.

The development of eco-friendly solutions based on silanes and nanoparticles for buildings and heritage consolidation Call name: PNCDI IV, SP 5.7.1 - Proiect de transfer la operatorul economic
PN-IV-P7-7.1-PTE-2024-0522 2025 - 2027

Role in this project:

Coordinating institution: POPP & ASOCIATII S.R.L.

Project partners: POPP & ASOCIATII S.R.L. (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA NAȚIONALĂ DE ȘTIINȚĂ ȘI TEHNOLOGIE POLITEHNICA BUCUREȘTI (RO)

Affiliation:

Project website:

Abstract:

The aim of the project consists of the transfer and development of a consolidation technology (based on innovative nanomaterials with self-healing properties and antimicrobial effects), dedicated to different types of materials from the composition of buildings and monuments. Considering in particular immovable heritage objectives), to an economic agent with experience in creating and applying solutions for the consolidation of such objectives (Popp & associations - POPP), to increase its economic competitiveness, as well as its implementation in targeted sites, in an integrated monitoring/consolidation technology, having as the final target the implementation of a viable technology for the consolidation of heritage buildings. The proposed innovative solutions will benefit from the synergism of the nanoparticles and the mixture of siloxanes-acrylic resins optimized in this sense.

Innovative approach for the protection of medicinal and aromatic plant crops - between circular bioeconomy and nanotechnology Call name: PNCDI IV, SP 5.7.1 - Proiect experimental demonstrativ
PN-IV-P7-7.1-PED-2024-0318 2025 - 2027

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); HOFIGAL EXPORT IMPORT SA (RO)

Affiliation:

Project website:

Abstract:

Combining natural extracts and nanomaterials can result in synergistic effects (where the antimicrobial properties of metals complement the biostimulant activities of plant-derived compounds), amplifying the benefits of both approaches. Thus, incorporating plant-derived compounds into nanocarriers can enhance their stability and bioavailability, ensuring a more sustained and effective delivery to plants. This integrated approach holds great potential for sustainable and efficient agriculture. This synergy creates a balanced formulation that not only protects plants from pathogens, but also enhances their overall growth and resilience.The project “Innovative approach for the protection of medicinal and aromatic plant crops - between circular bioeconomy and nanotechnology” (BioEcoNan) proposes a circular approach for the protection and enhancement of medicinal and aromatic plant crops, in which the vegetal wastes of a plant are used to develop modern tools for its own protection. The resulting solution (incorporating vegetal wastes and phytosynthesized nanomaterials) will act not only as a protection against the biocenotic stress agents (particularly the fungal and bacterial diseases), but also as a biostimulant, thus increasing not only the crop yield, but also the overall use of plants.

Transdisciplinary approach for the modern formulation of construction materials, a paradigm shift in the protection of immovable cultural heritage Call name: PNCDI IV, SP 5.7.1 - Proiect experimental demonstrativ
PN-IV-P7-7.1-PED-2024-0286 2025 - 2027

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CEPROCIM S.A. (RO)

Affiliation:

Project website:

Abstract:

Ancient monuments and structures endorse our historical past, bearing testimony to past events, concerns for the preservation and enhancement of the cultural heritage in the past decade being a challenge for the specialists. The main scientific objective of the project is to propose a promising, cost-effective and environmentally friendly alternative to the currently used solutions, with multi-valent use (both for cultural heritage protection and for civil constructions with special requirements, such as hospitals, etc.) based on development of technologies for obtaining constructions materials (plastering mortars, cement, plaster) with biocidal and photocatalytic properties, due to its enrichment with natural compounds and metallic nanoparticles obtained via “green chemistry routes” from natural resources (plant extracts). The challenge of the project is to obtain tuned morphologies of the metallic nanoparticles and to find optimal ratio of the component of the construction material (ratio solid: liquid), in order to obtain a maximum antibacterial effect (an important factor is the tendency of nanoparticles to aggregate and agglomerate, which significantly influences their effectiveness; the optimal use and dispersion of nanoparticles, in quantities that ensure the antibacterial properties of the building material, while maintaining the mechanical parameters at least at the same level).

Zirconium-modified magnetic sol-gel hybrid materials for advanced heavy metal removal from wastewater Call name: PNCDI IV, SP 5.7.1 - Proiect experimental demonstrativ
PN-IV-P7-7.1-PED-2024-1069 2025 - 2026

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); EDAS-EXIM SRL (RO)

Affiliation:

Project website:

Abstract:

The project aims to achieve and test a demonstrative model for the technology of obtaining highly efficient materials to reduce the effect of water pollution with heavy metals (arsenic, chromium, and lead). Zirconium adsorbent materials are efficient for this purpose. Therefore, a technology for obtaining innovative hybrid materials, i.e., Zirconium-modified Sol-Gel Magnetic Particles (SGMPs-Zr), will be developed using a completely new approach. An advanced purification efficiency is estimated as adsorption properties synergize with magnetic ones. In addition, the magnetite allows a more straightforward recovery of the spent adsorbent. Sol-Gel Magnetic Particles (SGMPs) with magnetite content are first prepared and then modified with zirconium after being chemically activated by reaction with diamines (commercial or PET-derived). Thus, PET aminolysis will be assayed for financial benefits and eco-impact. The mechanism of action of SGMPs-Zr considers the targeted heavy metal, and therefore, validation will be carried out first by testing synthetic wastewater, then industrial wastewater. The complementarity of the two partners' knowledge creates adequate premises for a complete study with benefits for meeting the project goals. The results of the studies can be transferred to the economic agents on water, providing them with an eco-technology that replaces the classic technologies.

Next generation method for studying redox signaling in plants and screening biostimulant potential formulations applied to plants: bimodal sensors Call name: PNCDI IV, SP 5.7.1 - Proiect experimental demonstrativ
PN-IV-P7-7.1-PED-2024-1966 2025 - 2026

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); SYNTECH RESEARCH AGRICO SRL (RO)

Affiliation:

Project website:

Abstract:

Plant biostimulants (PBs) are any substance or microorganisms that enhance the nutrition efficiency of plants, by stimulating their metabolism, improving crop yield, or reducing the impact of abiotic stresses. Nowadays PBs are unfortunately developed by hazard, and this led to gaps between bioeconomy and science, adding to climate change. Developing PBs by design means that the mode of action should be understood, and literature nowadays is scarce. Internal regulation cascades in plants involves different processes, such as redox signaling in stress conditions. Reactive oxygen/nitrogen species (ROS/RNS, mainly peroxynitrite, PON) are part of this redox signaling and their detection in plants would make things clearer, helping biostimulant development. EC-SER(o)S is proposing a unique unstudied bimodal analytical method composed of Electrochemistry (EC) and Surface Enhanced Raman Spectroscopy (SERS), by adaptation of EC for PON to SERS, using non-plasmonic graphene and phthalocyanine-based materials. After computing theoretical vibrations of PON/ROS, sensors development will be approached with EC-SERS, to extract complimentary information. Formulations of fertilizer/biostimulant compositions will be used to treat model plants/controlled crops. After calibration and quantification of PON/ROS the technology will be tested and validated to plants extracts/plant tissues/entire parts of plants for studying redox signaling in plants and screening biostimulant potential formulations.

Through nanotechnology towards the next generation dental restorative materials Call name: P 4 - Proiecte de cercetare exploratorie - PCE-2021
PN-III-P4-PCE-2021-0292 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://icechim.ro/project/nanodent_en/

Abstract:

The acidic attack from cariogenic bacteria found in dental plaque biofilm growth over the tooth is responsible for dental caries, also known as tooth decay, which is a biofilm-dependent infectious disease that damages teeth by minerals loss and presents a high incidence of clinical restorative polymeric fillings. The complexity of oral biofilms contributes to the difficulty in developing effective novel dental materials. Oral cavity represents an ideal environment for the microbial cell growth, persistence, and dental plaque establishment. When the complexity and volume of biofilms from the gingival crevice increase, chronic pathological conditions such as gingivitis and periodontitis can occur, predisposing to a wide range of complications. In this context, nanotechnology has potential to be explored in the development of bioactive dental materials to reduce or modulate the activities of caries-related bacteria. The project NanoDent proposes an original recipe based on nanometric phosphatic compounds enriched with phytosynthesized metallic nanoparticles and natural bioactive compounds, with simultaneous antibacterial and enhanced mechanical properties as a potential dental restorative material. The validation of the proposed technologies to obtain novel materials will be obtained via third-parties studies, performed through subcontracting.

Formulations of protective cosmetic products obtained by applying integrated and sustainable bioeconomy approaches Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0273 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI (RO)

Affiliation:

Project website: https://icechim.ro/project/bioprotect_ro/

Abstract:

Fruit processing industries contribute more than 0.5 billion tons of

waste worldwide, and grape crops and its industrial products are one of

the main agro-economic activities in the world, with more than 60

million tons produced globally every year. The grape industry,

specifically the wine industry, is generating by-products rich in

nutrients, which are underutilized and often end up being polluters of

the environment. After grape juice extraction, the remaining materials

are currently not valued as highly profitable waste, being mainly

discarded in open areas, potentially causing environmental problems.

Chronic exposure of human skin to solar UV radiation is widely

recognized as the key factor responsible for photo-ageing. For these

reasons, the role of photoprotection is critical to avoid skin cancer and

others undesired effects.

In this context, the general objective of the project “Formulations of

protective cosmetic products obtained by applying integrated and

sustainable bioeconomy approaches - BioProtect” is to propose the use

of nanomaterials both as active ingredient and delivery system of

bioactive compounds (mixtures of phenolic compounds-rutin and

quercitin) recovered from grape by-products for development of UV

blocking cosmetic products. Target molecules obtained through green

technologies from grapes by-products can be used as potential active

UV blockers in cosmetic formulations being delivered by substituted

hydroxyapatite (with Fe - FeHAP). The use of FeHAP has a double role:

active ingredient with UV protection properties and delivery system for

the bioactive molecules.

The project starts from TRL 2 and aims to the validation at laboratory

scale of the technology (TRL 4). Validation of the proposed technical

solution will be performed by third parties.

Innovative multifunctional composites for the protection of cultural heritage objects Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0627 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation:

Project website: https://icechim.ro/project/inheritage_ro/

Abstract:

In the last decades, new perspectives have emerged among both specialists, and the general public, regarding the preservation and enhancement of the cultural heritage. Conservation-restoration contribute to the safeguarding and understanding of the cultural property that benefits present and future generations, in its historical and aesthetic sense, in its physical integrity, its context and its uses. In the last years, the specialists in the field of materials science proposed a series of innovative materials and methodologies, applied in different areas, including the diagnosis and conservation state monitoring or preventive measures, implemented in order to reduce the need for interventions. However, as the degradation processes of cultural heritage objects remain inevitable, the continuous development of advanced materials able to counteract specific degradation processes is also necessary. Thus, are needed thorough scientific studies in order to develop tailored formulation, in order to protect, preserve, and restore cultural heritage objects, and this represents a continuous challenge for the scientists, aiming to replace the current rather serendipitous approaches in restoration. In this context, the project “Innovative multifunctional composites for the protection of cultural heritage objects” (INHERITAGE) aims to develop novel multi-layer composite materials with multiple functions (consolidation, self-cleaning and anti-microbial) applicable for the conservation of different inorganic substrates.

Antimicrobial PU foam nanocomposites designed for biomedical applications, synthesized by radiation-assisted technology Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0423 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU INGINERIE ELECTRICA ICPE - CA BUCURESTI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU INGINERIE ELECTRICA ICPE - CA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO)

Affiliation:

Project website: http://www.icpe-ca.ro/puma/; https://icechim.ro/project/puma_ro/

Abstract:

New technologies, based on nanoparticles are continuously introduced and developed in a large area of application fields, among them, biomedical and pharmaceutic products. The scope of the present project is to prepare some nanocomposite materials with intrinsic antimicrobial properties and to characterize their functionality. The new materials intended to be synthesized in this project are innovative metal nanoparticles (Silver and Copper-Gold nanoparticles) uniformly dispersed in polyurethane (PU) foam. The technology used for nanoparticle synthesis, recently developed at INCDIE ICPE-CA, based on radiation-induced chemical transformations, is environmentally friendly, because no chemical reagents (besides the nanoparticle precursors) are required and no chemical wastes emerge from the process. Another aim of the project is to exploit/ valorize the results recently obtained within earlier research projects by developing new functional models of materials with high antimicrobial activity and wide efficiency spectrum. This type of materials can be used in a wide area of applications, in particular in hospital environments (as for example structural elements of hospital mattresses and toppers, pillows, floor mats, cover materials for different surfaces or as components of various medical items, such as catheters, hydrogel support for bandages (dressings) a.s.o.). Given the current pandemic context caused by SARS CoV-2 and high percentage of nosocomial infections in hospitals, the project results will help to reduce the effects caused by such health crises, improving the health of patients and medical staff. On the other hand, given the multitude of practical applications of these polyurethane foams, the project results may open up new opportunities for the development of value-added antimicrobial PU based products (paints, footwear, dressings, etc.).

Due to its specificity, the project falls within the domain of public priority "Health".

Integrated Technology for the Advanced Removal of the Heavy Metals and of Arsenic from Complex Pollutants Matrices by Using Adsorbing Nanomaterials Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0309 2022 - 2024

Role in this project:

Coordinating institution: I.C.P.E. BISTRITA S.A.

Project partners: I.C.P.E. BISTRITA S.A. (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO); AQUATIM S.A. (RO)

Affiliation:

Project website: https://icpebn.ro/uploads/cms/2022_OXYADS/Oxyads_RST_Etapa3.pdf

Abstract:

The project goal is to transfer (towards ICPE Bistrita S.A.) and develop an innovative technology for depolluting the waters coming from drinking sources containing heavy metals and As into a complex pollutants matrix. The technology will be developed at the TRL 6 technological level, and implemented as a pilot plant at the headquarters of an important regional operator in the field of water treatment and supply (Aquatim S.A.). Considering a complex water pollution both by metals (Fe, Mn) and nitrogen compounds (e.g.the ammonium ion NH4+) and in the presence of a natural organic matrix, the elimination of such pollutants simultaneously with the removal of arsenium is a task nearly impossible to carry out via the actual technologies under reasonable operational and energetic efficiency circumstances. It is proposed an innovative integrated technology using synergic stages of advanced oxidation (catalytic ozonation) with on-site produced oxidising agents, integrated with a filtering / biofiltering stage (for the removal of ammonium and the retention of the oxidising products) and of an adsorption step based of adsorbing nanomaterials for the targeted elimination of As. An additional element of novelty is represented by the utilisation of the nanomaterials based on modified apatite systems, with a nanowire-type morphology, as adsorbing material for the efficient inexpensive removal of the arsenic species. The technology on which the project is based depart from a technology developed and validated at the laboratory level by the ICECHIM team, ensued from a Research Project within the NUCLEU programme - Nanotechnologies with Applications for Monitoring and Protecting the Environment (PN.19.23.03.02), which is the subject of an invention patent request - CBI A00380/2019- (OSIM) 'An Adsorbing Agent with Magnetic Properties, Based on an Apatite Material, for Treating the Waters Impurified by Organic and Inorganic Compounds, and the Method for Obtaining the Same'.

High performance phytosynthesized nanostructures as biosensor platforms for detecting pathogenic microorganism from food matrixe Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0042 2022 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: http://nanobiopat.chimie.upb.ro

Abstract:

Present project proposal “High performance phytosynthesized

nanostructures as biosensor platforms for detecting pathogenic

microorganism from food matrixes” is based on a modern and “green ”

method of obtaining mono and bi metallic nanostructures (mono and

bimetallic gold, silver copper nanoparticles) with the help of natural

extracts from cruciferous vegetables, in order to obtain sensing

platforms with high selectivity and specificity able to detect microbial

pathogens from food matrixes. The absolute novelty of the proposed

solutions and the foreseen results allows us to hope that potential

stakeholders (identified during the project) will be eager to take over

and implement these technologies, leading to social and economic

benefits, together with an important contribution to the increase of life

quality. The formulated concept of the product (related to the obtaining

of mono and bimetallic phytosinthesized nanostructures) and the

technology (the development of the sensing platform for detecting

pathogenic microorganism from food matrixes) will be the basis of the

project development. In the project will take place the analytical and

experimental characterisation of the product and technology that will

be developed (referring to the obtaining of innovative nanostructures -

TRL 3), the project being finished with the validation of the proposed

technologies at laboratory scale, through analyses performed via

third-parties laboratories (TRL 4). After the project implementation

period and protection of the technologies through patents, the

consortium aims at large scale prototypes and demonstration of the

functionality of the proposed solutions in real-life systems (TRL 6).

TRANSDISCIPLINARY APPROACH FOR DEVELOPMENT OF TECHNOLOGICAL SOLUTIONS FOR TARGET COMPOUNDS RECOVERY FROM AGRO SIDE-STREAMS Call name: P 3 - SP 3.5 - Proiecte EUREKA Tradiţional (Network), EUREKA-Cluster, Eurostars
PN-III-P3-3.5-EUK-2019-0226 2020 - 2023

Role in this project:

Coordinating institution: HOFIGAL EXPORT IMPORT SA

Affiliation:

Project website: https://hofigal.eu/content/26-proiect-tardis-hofigal

Abstract:

The project TARDIS is proposed in the context of closing chains in bioeconomy, in order to obtain extracts with increased target bioactive content, with potential pharmaceutical applications (Pharmacoidea) and/or nutraceutical products (HOFIGAL). Biowaste valorisation is an attractive approach in the framework of the EU Waste Management policies and the development of a circular economy. Wastes from biostreams and different bio-based sources are being under-utilized as potential resource of valuable compounds.

The general objective of the project is to underline, optimize and apply an integrate technology of sustainable and enhanced production of natural extracts with high content of biological active compounds from side streams of agricultural industries applicable for obtaining smart formulations for disorders of the 21st century, for which continuous research is carried out.

The main idea of the project is to process plants by-products rich in nutritional and bioactive compounds into formulations to be used in pharma industry with the following benefits: the use of obtained extracts and target compounds for the prevention / treatment of age-related neurodegenerative disorders such as Alzheimer's disease; minimizing the amount of plant waste by recovering the target compounds from the by-products; increasing the potential of the pharmaceutical and food market by designing new functional ingredients; increasing the quality of life.

The project will provide the necessary support for creating and developing a complementary research chain in bio-economy (industry, pharmacy, agriculture) that aims to achieve a high level of internationally recognized expertise. The project demonstrates an integrated cascading concept including pre-treatment, optimized extraction and separation technologies.

Evaluation of the exploatation potential Potential of Porous Materials in the tREatment of Microbiota-related dISeasEs - PREMISE Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4018 2020 - 2022

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL DE VIRUSOLOGIE "STEFAN S.NICOLAU" (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.micronanotech.ro/evaluarea-potentialului-de-exploatare-a-materialelor-poroase-in-tratarea-disbiozelor-microbiotei/

Abstract:

The scope of the current project proposal is to develop novel micro- and mesoporous materials (MMMs) using recent synthesis methods and to further functionalize these materials for developing better performances in order to be used as drug delivery systems (DDS), especially for microbiota-related diseases. These drug delivery systems are developed for oral administration and are expected to be protected within the stomach and maintain their activity until reach the desired site. Even if these drug delivery platforms are extensively exploited in the literature for several types of applications as DDS (hosting anticancer, anti-infectious or analgesic agents), the field of microbiota is only marginally treated. Nowadays, especially in the case of children, the awareness about the importance of the microbiota is well known, therefore after an antibiotic treatment, the prescription of probiotics is frequently needed. In the project’s boundaries, natural substances (polyphenols and vitamins) used as biological active agents will be loaded into the porous platforms, in order to assure a positive feedback to the microbiota due to the antioxidant, antimicrobial, anti-inflammatory and anticancer activities. In recent years, great emphasis has been placed on the development of micro and mesoporous materials loaded with biological active agents, but few research papers discuss the impact of functionalized MMMs on microbiota. In the current project, the main goal is to develop innovative MMMs with enhanced pore system able to host and deliver biological active agents (vitamins and polyphenols are expected to be used) for the treatment of the microbiota-related diseases. because most polyphenols have low solubility, two innovative delivery systems will be developed in order to assure triggering delivery / smart delivery.

Comprehensive Approach to support Precision Agriculture and environmental management through satellite technologies and classic methods of investigation Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3495 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://environment.inoe.ro/article/253/about-capa

Abstract:

The project ‘Comprehensive Approach to support Precision Agriculture and environmental management through satellite technologies and classic methods of investigation – CAPA’, addresses a major direction of the 21st century, namely, smart agriculture, bringing new insights into how the climate affects the phenological cycle of crops (through the occurrence of extreme events) and it also contributes to understanding the role of different air pollutants (such as greenhouse gases) in crop development. The project proposes the realization of synergies of the scientific activities integrating data on the complex eco-agro-system-culture relations, obtained by applying a conglomerate of methods and techniques (space technologies, the study of pollutants at the level of air, water, soil and plants), for a modern management of agricultural crops, in the context of intelligent agriculture. At the international level, smart agriculture is also based on the optimized management of the inputs according to the real needs of the crops, for their management and the reduction of the use of fertilizers, fungicides, pesticides and water resources. At the national level, the exploitation of satellite records in the field of agricultural management has not yet a significant spread, being used mainly in applications dedicated to environmental protection, forestry, territorial planning or in the military field. In this context, the project proposes the application and integration of spatial technologies together with in situ and ex situ analyses in the intelligent management of agriculture to monitor certain types of agricultural crops (from a pilot site), thus allowing the development of a successful model for better capitalization. of available resources.

Green technology for pharmaceuticals removal from water using eco-friendly oxidation catalysts Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3166 2020 - 2022

Role in this project:

Coordinating institution: UNIVERSITATEA BUCURESTI

Project partners: UNIVERSITATEA BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); I.C.P.E. BISTRITA S.A. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.avramescu-sorin-marius.eu/greencatox/#

Abstract:

Catalytic ozonation is a highly efficient process for removing most resistant organic pollutants from water and is a key process in wastewater treatment. Improving these technology in order to comply with green chemistry challenges is an important goal purification industry. Catalysts are the core of the process and, in the last decade, numerous studies and patents proposed a large range of materials for better ozone transformation into hydroxyl radicals and performing complete oxidation of the organic substrate. This project proposes a new and innovative class of ozonation catalysts with a morphology that assures an easy contact of ozone and pollutants with solid surface (thin-films) and green and cheaper technology for catalyst preparation using plant extracts instead of harmful chemical reagents (borohydride and organic solvents)

AI & EARTH OBSERVATION BASED SERVICES FOR CULTURAL HERITAGE MONITORING Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2019-0579 2020 - 2022

Role in this project:

Coordinating institution: GMV INNOVATING SOLUTIONS S.R.L.

Project partners: GMV INNOVATING SOLUTIONS S.R.L. (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://airfareproject.ro:49337/

Abstract:

Preservation of historic monuments and archaeological sites has a strategic importance for maintaining local cultural identity, encouraging a sustainable exploitation of cultural properties and creating new social opportunities. Cultural heritage objectives are often exposed to degradation due to natural and anthropogenic impacts. The AIRFARE project will implement, test and promote responsiveness solutions for effective resilience of cultural heritage against identified risks by exploiting the benefits of Earth Observation data wide availability and capabilities.

In this scope, specific EO data analysis tools will be used in order to construct a catalogue of services for cultural heritage monitoring, by integrating classical methodologies such as classification, change detection or multi-temporal interferometry with Artificial Intelligence/Machine Learning algorithms. These AI/ML processing algorithms are mature enough to be adapted to be implemented in the EO data processing pipelines in order to be used in the provision of services for cultural heritage monitoring.

A preliminary set of services that AIRFARE could deliver were identified in the proposal based on previous activities / pilot services performed by the university and the R&D institute partners: land-use maps, ground motion detection, archaeological sites, monitoring urban sprawl monitoring, illegal building near heritage sites, flood risk, local conditions, etc.

The AIRFARE project will extend this list, perform a trade-off analysis and further identify associated operational requirements for the services by involving relevant stakeholders such as ministries, institutes, administrators or owners of cultural heritage sites. Based on the outcomes, the algorithms will be selected, adapted and implemented. Lastly, the services will be implemented based on a GMV proprietary platform, tested and validated in an operational environment.

Water treatment from sources contaminated with nitrates and chlorinated organic compounds using integrated catalytic reduction / oxidation and biofiltration processes Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2019-0222 2020 - 2022

Role in this project:

Coordinating institution: I.C.P.E. BISTRITA S.A.

Project partners: I.C.P.E. BISTRITA S.A. (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); AKRO SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.icpebn.ro/ro/pagini/75-proiect-pn-iii-p2-2-1-pte-2019-0222.html

Abstract:

The project goal is the transfer (to ICPE Bistrita S.A.) and the development of an innovative water treatment technology for drinking water from sources contaminated with nitrates and chlorinated organic compounds. The technology will be developed at the technological level TRL 6 and implemented in the industrial environment at pilot installation in a water treatment plant. Considering a complex pollution of water with both nitrates and chlorinated organic compounds in the presence of a natural organic water matrix, its treatment becomes particularly difficult with the existing industrial technologies, under under reasonable operational and energetic efficiency circumstances and without obtaining toxic by-products. The project proposes an innovative water treatment technology using integrated processes of catalytic reduction / oxidation (conversion of nitrates and organochlorinated compounds / ammonium oxidation) and biofiltration (biological conversion of ammonium) that act synergistically, without the use of chemical reagents, with oxidizing agents produced in site (ozone). For the catalytic stage, innovative catalysts, of bimetallic type, deposited on a styrene-divenylbenzene resin will be used. The technology underlying the project starts from a technology developed and validated at the laboratory scale (TRL4) by the partner groups: P1 - UB (PROTMED) and P2 - ICF "Ilie Murgulescu" resulting from a research project funded under the program PNII-PCCA no. 100/2012, (Integrated procedure for the elimination of nitrates and organochlorine pesticides from contaminated natural waters as a result of agricultural activities), being the subject of a patent application CBI A / 00872/2016.

Increasing the institutional bioeconomic research capacity for innovative exploitation of local plant resources to obtain horticultural products with high added value Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0332 2018 - 2021

Role in this project:

Coordinating institution: UNIVERSITATEA PITESTI

Project partners: UNIVERSITATEA PITESTI (RO); INSTITUTUL DE CERCETARE-DEZVOLTARE PENTRU POMICULTURA MARACINENI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU BIOTEHNOLOGII IN HORTICULTURA STEFANESTI-ARGES (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); STATIUNEA DE CERCETARE-DEZVOLTARE PENTRU POMICULTURA CONSTANTA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE CRAIOVA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE IN SUDURA SI INCERCARI DE MATERIALE - ISIM TIMISOARA (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://www.upit.ro/ro/academia-reorganizata/facultatea-de-stiinte-educatie-fizica-si-informatica/departamente-la-nivelul-facultatii-de-stiinte-educatie-fizica-si-informatica/departamentul-stiinte-ale-naturii2/proiect-biohortinov

Abstract:

The complex project Increasing the institutional bioeconomic research capacity for innovative exploitation of local plant resources to obtain horticultural products with high added value comprises the following four projects:

Project 1."Complex electronic system with intelligent algorithms for data processing used for monitoring the developing conditions of water and biocenotic stresses, for warning about their presence and preventing them in horticulture"

Project 2."Multisensory quantification of water and biocenotic stress in horticulture through phytomonitoring and early warning in climate change conditions"

Project 3."Development of plant extracts and innovative phytosynthesized nanostructured mixtures with phytotherapeutical applications aimed at eliminating the biocenotic stress in horticultural crops"

Project 4."Innovative technologies for advanced processing of plant resources from pomiculture and viticulture"

The objectives of the project aim to develop the research capacity of the public organizations involved. Thus, upon the completion of the projects these organizations should meet the following outcome indicators: 1) employing new staff in research positions; 2)training the new and old employees through initial research training courses and specialist courses offered by each of the partners in their own field of competence (using the logistics of the learning resource centers); 3)obtaining new or significantly improved products/technologies/services; 4)structuring the offer for research and technological services and presenting it on the platform www.erris.gov.ro; 5)strengthening the capacity of the partner institutions through recovery strategies such as training programmes (research)/specialization programmes and visits (short-term); 6)offering and performing research services using the available research infrastructure; 7)creating a common programme for the learning resource centers, correlated with the institutional development plan of each partner

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects